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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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The term of radiosurgery signifies any kind of single application of ionizing radiationenergy, in experimental biology or clinical medicine, aiming at the precise and completedestruction of chosen target structures containing healthy and/or pathological cells, withoutsignificant concomitant or late radiation damage to adjacent tissues. The goal of this radiosurgical pathology study is to explore the short- and long-term effects of high-dose ionizingradiation on neural tissue and its pathologies with histological, electron-microscopical, tissue culture and biological-biochemical methods. Radiosurgical pathology focuses its scope andmicroscope for histological, cell, genetic and molecular changes in the human body and experimental animals, or in tissue cultures and other in vitro experiments, generated by the ionizing radiation delivered from radiosurgical devices.

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