Human Papillomavirus: Bench to Bedside
Human papillomavirus (HPV) infection transcends multiple fields of science and medicine. The management of HPV-related disease is demanding and often requires a persistent multimodal approach involving various medical disciplines. In this volume, experts present a comprehensive view of HPV research with an emphasis on clinical presentations, diagnosis, management and vaccine development. The state of the art in molecular biology is provided in addition to discussions on clinical morphology and the utility of dermatoscopy in identifying HPV disease. In a multidisciplinary approach to dermatological, plastic and reconstructive, gynecological, otolaryngological and colorectal management, different treatment strategies are highlighted. Finally, Dr. Neil Christensen discusses viral immunology, and the difficulties and successes in the development of an HPV vaccine. Bringing together basic science and clinical information on HPV, this book is an excellent resource and reference for all researchers and clinicians who encounter human papillomavirus-related disease.
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Table of Contents
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1 - 18: Human Papillomavirus Genomics: Past, Present and FutureByAriana Harari;Ariana HarariaDepartments of Microbiology and Immunology,Search for other works by this author on:Robert D. BurkRobert D. BurkaDepartments of Microbiology and Immunology,bPediatrics,cObstetrics, Gynecology and Women's Health, anddEpidemiology and Population Health, Albert Einstein College of Medicine, Bronx, N.Y., USASearch for other works by this author on:
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19 - 32: The Biology of Human PapillomavirusesByHarrison P. Nguyen;Harrison P. NguyenaBaylor College of Medicine,Search for other works by this author on:Marigdalia K. Ramírez-Fort;Marigdalia K. Ramírez-FortbCenter for Clinical Studies, andSearch for other works by this author on:Peter L. RadyPeter L. RadycDepartment of Dermatology, University of Texas Health Science Center at Houston, Houston, Tex., USASearch for other works by this author on:
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33 - 46: Viral OncogenesisByHung Q. Doan;Hung Q. DoanaUniversity of Texas Medical Branch, Galveston, Tex., andSearch for other works by this author on:Marigdalia K. Ramírez-Fort;Marigdalia K. Ramírez-FortbCenter for Clinical Studies andSearch for other works by this author on:Peter L. RadyPeter L. RadycUniversity of Texas Medical School, Houston, Tex., USASearch for other works by this author on:
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47 - 57: Pathogenesis of Infection by Human PapillomavirusBySarah A. Brendle;Sarah A. BrendleDepartments of Pathology and Microbiology and Immunology, Jake Gittlen Cancer Research Foundation, Penn State College of Medicine, Hershey, Pa., USASearch for other works by this author on:Stephanie M. Bywaters;Stephanie M. BywatersDepartments of Pathology and Microbiology and Immunology, Jake Gittlen Cancer Research Foundation, Penn State College of Medicine, Hershey, Pa., USASearch for other works by this author on:Neil D. ChristensenNeil D. ChristensenDepartments of Pathology and Microbiology and Immunology, Jake Gittlen Cancer Research Foundation, Penn State College of Medicine, Hershey, Pa., USASearch for other works by this author on:
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58 - 74: Host Responses to Infection with Human PapillomavirusByMargaret A. Stanley;Margaret A. StanleyDepartment of Pathology, University of Cambridge, Cambridge, UKSearch for other works by this author on:Jane C. SterlingJane C. SterlingDepartment of Pathology, University of Cambridge, Cambridge, UKSearch for other works by this author on:
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75 - 91: The Epidemiology of Human PapillomavirusesByAlan G. Nyitray;Alan G. NyitrayaCenter for Infectious Diseases, University of Texas School of Public Health at Houston, Houston, Tex., USA;Search for other works by this author on:Michelle R. IannaconeMichelle R. IannaconebCancer and Population Studies Group, QIMR Berghofer Medical Research Institute, Brisbane, Qld., AustraliaSearch for other works by this author on:
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92 - 97: Cutaneous Human Papillomavirus Infection: Manifestations and DiagnosisByPhilipp Tschandl;Philipp TschandlaDepartment of Dermatology, Medical University of Vienna, Vienna, Austria;Search for other works by this author on:Cliff Rosendahl;Cliff RosendahlbSchool of Medicine, University of Queensland, Brisbane, Qld., AustraliaSearch for other works by this author on:Harald KittlerHarald KittleraDepartment of Dermatology, Medical University of Vienna, Vienna, Austria;Search for other works by this author on:
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98 - 122: Genitoanal Human Papillomavirus Infection and Associated NeoplasiasByGerd GrossGerd GrossDepartment of Dermatology and Venereology, University of Rostock, Rostock, GermanySearch for other works by this author on:
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123 - 131: Epidermodysplasia Verruciformis
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132 - 153: Human Papillomavirus Infections of the Oral Mucosa and Upper Respiratory TractByHarrison P. Nguyen;Harrison P. NguyenaBaylor College of Medicine,Search for other works by this author on:Kayla L. McNiece;Kayla L. McNiecebUniversity of Texas Health Science Center at Houston andSearch for other works by this author on:Angela A. Duong;Angela A. DuongcUniversity of Texas at Austin, Austin, Tex., andSearch for other works by this author on:Farhan KhanFarhan KhandCenter for Clinical Studies, Houston, Tex., USASearch for other works by this author on:
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154 - 165: Human Papillomavirus and ImmunosuppressionByUlrike Wieland;Ulrike WielandaInstitute of Virology, National Reference Center for Papilloma- and Polyomaviruses, University of Cologne, Cologne, andSearch for other works by this author on:Alexander Kreuter;Alexander KreuterbDepartment of Dermatology, Venereology and Allergology, Helios St. Elisabeth Hospital Oberhausen, Oberhausen, GermanySearch for other works by this author on:Herbert PfisterHerbert PfisteraInstitute of Virology, National Reference Center for Papilloma- and Polyomaviruses, University of Cologne, Cologne, andSearch for other works by this author on:
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166 - 174: Laboratory Diagnosis of Human Papillomavirus InfectionByHans IkenbergHans IkenbergCytomol, Frankfurt, GermanySearch for other works by this author on:
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175 - 185: Management of Cutaneous Human Papillomavirus Infection: PharmacotherapiesByMarigdalia K. Ramírez-Fort;Marigdalia K. Ramírez-FortaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:Shiu-Chung Au;Shiu-Chung AuaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:Syed Ali Javed;Syed Ali JavedbSchool of Medicine, University of Texas Health Science Center at Houston, Houston, Tex., USASearch for other works by this author on:Daniel S. LooDaniel S. LooaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:
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186 - 196: Management of Cutaneous Human Papillomavirus Infection: SurgeryByMarigdalia K. Ramírez-Fort;Marigdalia K. Ramírez-FortaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., and Departments ofSearch for other works by this author on:Ernest K. MandersErnest K. ManderscPlastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pa., USASearch for other works by this author on:
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197 - 215: Management of Cutaneous Human Papillomavirus Infection in Immunocompromised PatientsBySowmya Varada;Sowmya VaradaaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:Mark Posnick;Mark PosnickaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:Dana Alessa;Dana AlessaaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andSearch for other works by this author on:Marigdalia K. Ramírez-FortMarigdalia K. Ramírez-FortaDepartment of Dermatology, Tufts Medical Center, Boston, Mass., andbCenter for Clinical Studies, Houston, Tex., USASearch for other works by this author on:
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216 - 224: Management of Human Papillomavirus-Related Gynecological MalignanciesByViola A. Heinzelmann-Schwarz;Viola A. Heinzelmann-SchwarzaGynecological Cancer Center,Search for other works by this author on:Francis JacobFrancis JacobcGynecological Cancer Group, Women's University Hospital, University of Basel, Basel, SwitzerlandSearch for other works by this author on:
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225 - 235: Management of Human Papillomavirus-Related Anal and Colon CancerByAngela Yen Moore;Angela Yen MooreaArlington Center for Dermatology andcBaylor University Medical Center, Dallas, Tex.,dUniversity of Texas Medical Branch, Galveston, Tex., andSearch for other works by this author on:Lana X. Tong;Lana X. TongeDavid Geffen School of Medicine at the University of California, Los Angeles, Calif., USASearch for other works by this author on:Todd MooreTodd MoorebArlington Colorectal Clinic, Arlington Center for Dermatology, Arlington Research Center, Arlington, Tex.,Search for other works by this author on:
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236 - 251: Management of Human Papillomavirus-Related Head and Neck CancerByA.M. Coughlin;A.M. CoughlinaDepartment of Otolaryngology, Head and Neck Surgery andSearch for other works by this author on:S. Qiu;S. QiubDepartment of Pathology, University of Texas Medical Branch, Galveston, Tex., USASearch for other works by this author on:M.P. UnderbrinkM.P. UnderbrinkaDepartment of Otolaryngology, Head and Neck Surgery andSearch for other works by this author on:
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252 - 264: Vaccines and Immunization against Human PapillomavirusByNeil D. Christensen;Neil D. ChristensenDepartments of Pathology and Microbiology and Immunology, Penn State Hershey Medical Center, College of Medicine, Hershey, Pa., USASearch for other works by this author on:Lynn R. BudgeonLynn R. BudgeonDepartments of Pathology and Microbiology and Immunology, Penn State Hershey Medical Center, College of Medicine, Hershey, Pa., USASearch for other works by this author on: