Oral Cephalosporins
This volume provides an excellent survey of the chemistry, microbiology, pharmacology and clinical use of the oral cephalosporins in general and the newer agents in particular. The cephalosporins have long provided satisfactory treatment for many disorders without causing serious side effects; and over the past fifty years forms with different antimicrobial, pharmacologic and toxicologic properties have been developed. Despite the broad spectrum of their activity against a large variety of gram-positive and gram-negative bacteria, the third-generation oral cephalosporins including the prodrug esters do not work against Pseudomonas aeruginosa, methicillin-resistant staphylococci, enterococci or Bacteroides species. Many, however, are suitable for treating infections of the respiratory and urinary tracts and of the skin and its structure, as well as certain sexually-transmitted diseases. Authors consider other possible uses, against multi-resistant Enterobacteriaceae for instance, but also point out the limitations of the oral cephalosporins. For those working in the fields of infectious disease, bacteriology, chemotherapy, pharmaceutics and pharmacokinetics, this book is a valuable source of authoritative information.
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Table of Contents
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1 - 7: Systematics of Beta-Lactams: Chemical Properties and Structure Activity Relationship of Oral CephalosporinsByF. Kees;F. KeesLehrstuhl für Pharmakologie der Universität Regensburg, Regensburg, GermanySearch for other works by this author on:H. GrobeckerH. GrobeckerLehrstuhl für Pharmakologie der Universität Regensburg, Regensburg, GermanySearch for other works by this author on:
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8 - 33: Pharmacology and Toxicology of Oral CephalosporinsByGiuliana Gialdroni GrassiGiuliana Gialdroni GrassiChair of Chemotherapy, University of Pavia, ItalySearch for other works by this author on:
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34 - 71: Clinical Pharmacokinetics of Oral CephalosporinsByKlaus Stoeckel;Klaus StoeckelaCLINPHARM SUPPORT, Basel, Switzerland;Search for other works by this author on:William L. Hayton;William L. HaytonbOhio State University, Division of Pharmaceutics and Pharmaceutical Chemistry, Columbus, Ohio;Search for other works by this author on:David J. EdwardsDavid J. EdwardscWayne State University, College of Pharmacy, Detroit, Mich., USASearch for other works by this author on:
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72 - 109: Microbiology of Oral CephalosporinsByW. CullmannW. CullmannBürgerhospital/Zentrallabor, Stuttgart, DeutschlandSearch for other works by this author on:
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110 - 122: Oral Cephalosporins in Upper Respiratory InfectionsByEugene Leibovitz;Eugene LeibovitzPediatric Infectious Disease Unit, Ben-Gurion University of the Negev and the Faculty of Health Sciences, Soroka University Medical Center, Beer-Sheva, IsraelSearch for other works by this author on:Ron DaganRon DaganPediatric Infectious Disease Unit, Ben-Gurion University of the Negev and the Faculty of Health Sciences, Soroka University Medical Center, Beer-Sheva, IsraelSearch for other works by this author on:
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123 - 144: Oral Cephalosporins: Clinical Results in Lower Respiratory Tract InfectionsByErnesto Pozzi;Ernesto PozziClinical and Biological Sciences Department, Respiratory Diseases Division, University of Turin, ItalySearch for other works by this author on:Alessandro OlivaAlessandro OlivaClinical and Biological Sciences Department, Respiratory Diseases Division, University of Turin, ItalySearch for other works by this author on:
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145 - 159: Oral Cephalosporins: Clinical Results in Urinary Tract InfectionsByHelen GiamarellouHelen Giamarellou1st Department of Propaedeutic Medicine, Athens University School of Medicine, Athens, GreeceSearch for other works by this author on:
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160 - 182: Tolerability of Oral CephalosporinsByHans Lepper;Hans LepperInstitute of Pharmacology and Toxicology of the University of Erlangen-Nürnberg, Erlangen, GermanySearch for other works by this author on:Claus-Jürgen EstlerClaus-Jürgen EstlerInstitute of Pharmacology and Toxicology of the University of Erlangen-Nürnberg, Erlangen, GermanySearch for other works by this author on: