Clinical Recovery from CNS Damage
After decades of focusing on how to alleviate and prevent recurrence of acute CNS injuries, the emphasis has finally shifted towards repairing such devastating events and rehabilitation. This development has been made possible by substantial progress in understanding the scientific underpinnings of recovery as well as by novel diagnostic tools, and most importantly, by emerging therapies awaiting clinical trials. In this publication, several international experts introduce novel areas of neurological reorganization and repair following CNS damage. Principles and methods to monitor and augment neuroplasticity are explored in depth and supplemented by a critical appraisal of neurological repair mechanisms and possibilities to curtail disability using computer or robotic interfaces. Rather than providing a textbook approach of CNS restoration, the editors selected topics where progress is most imminent in this labyrinthine domain of medicine. Moreover, the varied background and origins of the contributors lend this book a truly global perspective on the current state of affairs in neurological recovery.
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Table of Contents
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1 - 8: Mechanisms of Functional Recovery after StrokeBySang-Bae Ko;Sang-Bae KoDepartment of Neurology, Seoul National University Hospital, Seoul, South KoreaSearch for other works by this author on:Byung-Woo YoonByung-Woo YoonDepartment of Neurology, Seoul National University Hospital, Seoul, South KoreaSearch for other works by this author on:
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9 - 25: Diagnostic Approach to Functional Recovery: Functional Magnetic Resonance Imaging after StrokeByInger Havsteen;Inger HavsteenaDepartments of Radiology andSearch for other works by this author on:Kristoffer H. Madsen;Kristoffer H. MadsencDanish Research Center for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSearch for other works by this author on:Hanne Christensen;Hanne ChristensenbNeurology, Copenhagen University Hospital Bispebjerg, Copenhagen, andSearch for other works by this author on:Anders Christensen;Anders ChristensenaDepartments of Radiology andSearch for other works by this author on:Hartwig R. SiebnerHartwig R. SiebnercDanish Research Center for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSearch for other works by this author on:
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26 - 35: Diagnostic Approach to Functional Recovery: Diffusion-Weighted Imaging and TractographyByEstelle Raffin;Estelle RaffinDanish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSearch for other works by this author on:Tim B. DyrbyTim B. DyrbyDanish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSearch for other works by this author on:
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36 - 44: Compensatory Contribution of the Contralateral Pyramidal Tract after Experimental Cerebral IschemiaByYusuke Takatsuru;Yusuke TakatsuruaDepartment of Integrative Physiology, Gunma University Graduate School of Medicine, MaebashiSearch for other works by this author on:Kayo Nakamura;Kayo NakamurabDivision of Homeostatic Development, National Institute for Physiological Sciences, OkazakicThe Graduate University for Advanced Studies, HayamaSearch for other works by this author on:Junichi NabekuraJunichi NabekurabDivision of Homeostatic Development, National Institute for Physiological Sciences, OkazakicThe Graduate University for Advanced Studies, HayamadCREST, Japan Science and Technology Agency, Kawaguchi, JapanSearch for other works by this author on:
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45 - 53: Compensatory Contribution of the Contralateral Pyramidal Tract after StrokeByNobuko Otsuka;Nobuko OtsukaaNeurology Division, Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita andSearch for other works by this author on:Kotaro Miyashita;Kotaro MiyashitaaNeurology Division, Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita andSearch for other works by this author on:Derk W. Krieger;Derk W. KriegercDepartment of Neurology, University of Copenhagen, Copenhagen, DenmarkSearch for other works by this author on:Hiroaki NaritomiHiroaki NaritomibDepartment of Neurology, Senri Chuo Hospital, Osaka, Japan;Search for other works by this author on:
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54 - 61: Regeneration of Neuronal Cells following Cerebral InjuryByTravis Dailey;Travis DaileyDepartment of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Fla., USASearch for other works by this author on:Naoki Tajiri;Naoki TajiriDepartment of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Fla., USASearch for other works by this author on:Yuji Kaneko;Yuji KanekoDepartment of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Fla., USASearch for other works by this author on:Cesar V. BorlonganCesar V. BorlonganDepartment of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Fla., USASearch for other works by this author on:
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62 - 68: Translational Challenge for Bone Marrow Stroma Cell Therapy after StrokeBySatoshi Kuroda;Satoshi KurodaaDepartment of Neurosurgery, University of Toyama, Toyama, andbDepartment of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, JapanSearch for other works by this author on:Kiyohiro HoukinKiyohiro HoukinbDepartment of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, JapanSearch for other works by this author on:
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69 - 75: Experimental Evidence and Early Translational Steps Using Bone Marrow Derived Stem Cells after Human StrokeByYukiko Kasahara;Yukiko KasaharaDepartment of Regenerative Medicine Research, Institute of Biomedical Research and Innovation, Kobe, JapanSearch for other works by this author on:Masafumi Ihara;Masafumi IharaDepartment of Regenerative Medicine Research, Institute of Biomedical Research and Innovation, Kobe, JapanSearch for other works by this author on:Akihiko TaguchiAkihiko TaguchiDepartment of Regenerative Medicine Research, Institute of Biomedical Research and Innovation, Kobe, JapanSearch for other works by this author on:
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76 - 87: Therapeutic Drug Approach to Stimulate Clinical Recovery after Brain InjuryByDerk W. KriegerDerk W. KriegerDepartment of Neurology, Stroke Center, Rigshospitalet, Copenhagen, DenmarkSearch for other works by this author on:
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88 - 94: Rehabilitation and PlasticityByAndreas R. LuftAndreas R. LuftDepartment of Neurology, University Hospital of Zurich, Zürich, SwitzerlandSearch for other works by this author on:
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95 - 100: A Brain-Computer Interface to Support Functional RecoveryByTroels W. Kjaer;Troels W. KjaeraDepartment of Clinical Neurophysiology, Rigshospitalet University Hospital, Copenhagen, andSearch for other works by this author on:Helge B. SørensenHelge B. SørensenbDepartment of Electrical Engineering, Technical University of Denmark, Lyngby, DenmarkSearch for other works by this author on:
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101 - 111: Novel Methods to Study Aphasia Recovery after StrokeByGesa Hartwigsen;Gesa HartwigsenaLanguage and Aphasia Laboratory, Department of Neurology, University of Leipzig, Leipzig, andbDepartment of Psychology, Christian-Albrechts-University Kiel, Kiel, Germany;Search for other works by this author on:Hartwig R. SiebnerHartwig R. SiebnercDanish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, DenmarkSearch for other works by this author on:
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112 - 121: Role of Repetitive Transcranial Magnetic Stimulation in Stroke RehabilitationByMichaela M. Pinter;Michaela M. PinterDepartment for Clinical Neurosciences and Preventive Medicine, Danube University Krems, Krems, AustriaSearch for other works by this author on:Michael BraininMichael BraininDepartment for Clinical Neurosciences and Preventive Medicine, Danube University Krems, Krems, AustriaSearch for other works by this author on:
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122 - 128: Influence of Therapeutic Hypothermia on Regeneration after Cerebral IschemiaByM.A. Yenari;M.A. YenariaDepartment of Neurology, University of California, and San Francisco Veterans Affairs Medical Center, San Francisco, Calif., USA;Search for other works by this author on:H.S. HanH.S. HanbDepartment of Physiology, Kyungpook National University School of Medicine, Daegu, Republic of KoreaSearch for other works by this author on:
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129 - 138: High Voltage Electric Potentials to Enhance Brain-Derived Neurotrophic Factor Levels in the BrainByHiroji Yanamoto;Hiroji YanamotoaLaboratory of Neurology and Neurosurgery andbDepartment of Neurosurgery, National Cerebral and Cardiovascular Research Center, andcDepartment of Cardiovascular Science, Division of Surgical Medicine, Osaka University Graduate School of Medicine, Suita, andSearch for other works by this author on:Yukako Nakajo;Yukako NakajoaLaboratory of Neurology and Neurosurgery andcDepartment of Cardiovascular Science, Division of Surgical Medicine, Osaka University Graduate School of Medicine, Suita, anddResearch Laboratory, Rakuwakai Otowa Hospital, Kyoto, JapanSearch for other works by this author on:Hiroharu Kataoka;Hiroharu KataokabDepartment of Neurosurgery, National Cerebral and Cardiovascular Research Center, andSearch for other works by this author on:Koji IiharaKoji IiharabDepartment of Neurosurgery, National Cerebral and Cardiovascular Research Center, andSearch for other works by this author on:
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139 - 147: Prevention of Post-Stroke Disuse Muscle Atrophy with a Free Radical ScavengerByHiroaki Naritomi;Hiroaki NaritomiaDepartment of Neurology, Senri Chuo Hospital, andSearch for other works by this author on:Hiroshi MoriwakiHiroshi MoriwakibDepartment of Stroke Neurology, Kansai Rosai Hospital, Osaka, JapanSearch for other works by this author on: