Uric Acid in Chronic Kidney Disease
Hyperuricemia is often associated with life-style related disorders such as diabetes mellitus, hypertension, and dyslipidemia, which, in turn, are major causes of CKD. Improved management of hyperuricemia is thus expected to be beneficial for both the general population and CKD patients. This book presents new information on uric acid in tubular transport, early recognition of renal lesions, genetic predisposition, preeclampsia, metabolic syndrome, diabetes, high blood pressure in the young, and the relationship with vitamin D. Moreover, the relationship between AKI and uric acid, as well as the rejection of renal transplants due to hyperuricemia, are discussed. This publication will be of interest to both general practitioners and researchers working in the field of CKD. It provides new insights into renal damage caused by hyperuricemia and into prevention and treatment possibilities.
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1 - 7: Renal Handling of Uric AcidByJorge Andrade Sierra;Jorge Andrade SierraaDepartment of Physiology, University Health Sciences Center (Centro Universitario de Ciencias de la Salud), University of Guadalajara, Guadalajara,bDepartment of Nephrology and Organ Transplant Unit, Hospital de Especialidades, Centro Medico Nacional de Occidente (CMNO), IMSS, Guadalajara, andcDepartment of Internal Medicine, Civil Hospital of Guadalajara “Dr. Juan I. Menchaca”, Guadalajara, MéxicoSearch for other works by this author on:Milagros M. Flores FonsecaMilagros M. Flores FonsecabDepartment of Nephrology and Organ Transplant Unit, Hospital de Especialidades, Centro Medico Nacional de Occidente (CMNO), IMSS, Guadalajara, andSearch for other works by this author on:
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8 - 16: Renal Effects of HyperuricemiaByCarlos Enrique Méndez LandaCarlos Enrique Méndez LandaDepartment of Nephrology, General Hospital and Medical Unit Ambulatory Care, Mexican Institute of Social Security, Mexico City, MexicoSearch for other works by this author on:
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17 - 24: The Pathophysiology of Uric Acid on Renal DiseasesByL. Gabriela Sánchez-LozadaL. Gabriela Sánchez-LozadaLaboratory of Renal Physiopathology, Department of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, MexicoSearch for other works by this author on:
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25 - 33: Uric Acid: The Unknown Uremic ToxinByAlejandro Treviño-BecerraAlejandro Treviño-BecerraUremic and Dialysis Clinic, México City, MéxicoSearch for other works by this author on:
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34 - 40: The Association between Serum Uric Acid and Renal Damage: The Takahata Study - New InsightsByTsuneo Konta;Tsuneo KontaaDepartment of Cardiology, Pulmonology, and Nephrology, andSearch for other works by this author on:Keita Kamei;Keita KameiaDepartment of Cardiology, Pulmonology, and Nephrology, andSearch for other works by this author on:Kazunobu Ichikawa;Kazunobu IchikawaaDepartment of Cardiology, Pulmonology, and Nephrology, andSearch for other works by this author on:Takamasa Kayama;Takamasa KayamabGlobal COE, Yamagata University School of Medicine, Yamagata, JapanSearch for other works by this author on:Isao KubotaIsao KubotaaDepartment of Cardiology, Pulmonology, and Nephrology, andSearch for other works by this author on:
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41 - 47: Significance of Hyperuricemia among Community-Based Screening ParticipantsByKunitoshi IsekiKunitoshi IsekiClinical Research Support Center, Tomishiro Central Hospital, Okinawa, JapanSearch for other works by this author on:
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48 - 55: Hyperuricemia and Progression of Chronic Kidney Disease: Role of Phenotype Transition of Renal Tubular and Endothelial CellsByDuk-Hee KangDuk-Hee KangDivision of Nephrology, Department of Internal Medicine, Ewha Woman's University College of Medicine, Ewha Medical Research Center, Seoul, KoreaSearch for other works by this author on:
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56 - 68: Time to Target Uric Acid to Retard Chronic Kidney Disease ProgressionByShunya Uchida;Shunya UchidaaDepartment of Internal Medicine, Teikyo University School of Medicine, Tokyo,Search for other works by this author on:Takanori Kumagai;Takanori KumagaiaDepartment of Internal Medicine, Teikyo University School of Medicine, Tokyo,bSupport for Community Medicine Endowed Chair, Teikyo University School of Medicine, Tokyo, andSearch for other works by this author on:Wen Xiu Chang;Wen Xiu ChangcDepartment of Nephrology, Tianjin First Center Hospital, Tianjin, ChinaSearch for other works by this author on:Yoshifuru Tamura;Yoshifuru TamuraaDepartment of Internal Medicine, Teikyo University School of Medicine, Tokyo,Search for other works by this author on:Shigeru ShibataShigeru ShibataaDepartment of Internal Medicine, Teikyo University School of Medicine, Tokyo,Search for other works by this author on:
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69 - 76: Uric Acid: The Lower the Better?ByGianni Bellomo;Gianni BellomoDepartment of Nephrology, USL 1 Regione Umbria, Perugia, ItalySearch for other works by this author on:Antonio SelviAntonio SelviDepartment of Nephrology, USL 1 Regione Umbria, Perugia, ItalySearch for other works by this author on:
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77 - 81: Gout: A Disease of KingsBySydney C.W. TangSydney C.W. TangDivision of Nephrology, Department of Medicine, The University of Hong Kong, Hong Kong, ChinaSearch for other works by this author on:
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82 - 87: Systemic Implications of HyperuricemiaByJuan A. Tamayo y OrozcoJuan A. Tamayo y OrozcoSenior professor - Head of the Renal Health Area in the Academic Secretariat from the National Institute of Public Health, S.S.A. Member of the National Academy of Medicine, Mexico City, MexicoSearch for other works by this author on:
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88 - 102: Uric Acid as a Cause of the Metabolic SyndromeByChristopher King;Christopher KingaDivision of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, andSearch for other works by this author on:Miguel A. Lanaspa;Miguel A. LanaspaaDivision of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, andSearch for other works by this author on:Thomas Jensen;Thomas JensenaDivision of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, andSearch for other works by this author on:Dean R. Tolan;Dean R. TolanbDepartment of Biology, Boston University, Boston, MA, USA;Search for other works by this author on:L. Gabriela Sánchez-Lozada;L. Gabriela Sánchez-LozadacLaboratory of Renal Physiopathology, INC Ignacio Chávez, Mexico City, MexicoSearch for other works by this author on:Richard J. JohnsonRichard J. JohnsonaDivision of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, andSearch for other works by this author on:
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103 - 109: Uric Acid and Diabetic Nephropathy RiskByMichael Mauer;Michael MaueraDepartment of Pediatrics and Medicine, University of Minnesota School of Medicine, Minneapolis, MN, andSearch for other works by this author on:Alessandro DoriaAlessandro DoriabResearch Division, Joslin Diabetes Center, Department of Medicine, Harvard School of Medicine, Boston, MA, USASearch for other works by this author on:
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110 - 115: Uric Acid in Pregnancy: New ConceptsByArmando Alberto Moreno Santillan;Armando Alberto Moreno SantillanaDepartment of Obstetrics, Obstetrics and Gynecology Hospital “Dr. Luis Castelazo Ayala” IMSS, Mexico City, Fellow of the American Congress of Obstetricians and Gynecologist;Search for other works by this author on:Jesus Carlos Briones Garduño;Jesus Carlos Briones GarduñobMember of the National Academy of Medicine, and Mexican Academy of Surgery, Fellow of the American College of Physicians, Mexico City, CMD in Obstetrics and Gynecology Department, General Hospital of Mexico “Dr. Eduardo Liceaga” SSA, Mexico City,Search for other works by this author on:Manuel Antonio Diaz de Leon PonceManuel Antonio Diaz de Leon PoncecMember of the National Academy of Medicine, and Mexican Academy of Surgery, Fellow of the American College of Physicians, Mexico City, MexicoSearch for other works by this author on:
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116 - 124: Uric Acid Renal Lithiasis: New ConceptsByFabiola Pazos PérezFabiola Pazos PérezDepartment of Nephrology, Specialty Hospital, National Medical Center XXI Century, Mexico City, MexicoSearch for other works by this author on:
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125 - 134: Clinical Significance of Serum Uric Acid Levels in Mexican Young AdultsByAraceli Alegría-Díaz;Araceli Alegría-DíazaDepartment of Nephrology, Hospital General de México, México City,Search for other works by this author on:Rafael Valdez-Ortiz;Rafael Valdez-OrtizaDepartment of Nephrology, Hospital General de México, México City,Search for other works by this author on:Miguel Murguía-Romero;Miguel Murguía-RomerobIztacala School of Graduate Studies, National Autonomous University of Mexico (FES-I. UNAM), Tlalnepantla,cNational Laboratory in Health: Molecular Diagnosis and Environmental Effect in Chronic-Degenerative Diseases, National Autonomous University of Mexico (UNAM), Tlalnepantla, México;Search for other works by this author on:Rafael Jiménez-Flores;Rafael Jiménez-FloresbIztacala School of Graduate Studies, National Autonomous University of Mexico (FES-I. UNAM), Tlalnepantla,cNational Laboratory in Health: Molecular Diagnosis and Environmental Effect in Chronic-Degenerative Diseases, National Autonomous University of Mexico (UNAM), Tlalnepantla, México;Search for other works by this author on:Rafael Villalobos-Molina;Rafael Villalobos-MolinabIztacala School of Graduate Studies, National Autonomous University of Mexico (FES-I. UNAM), Tlalnepantla,cNational Laboratory in Health: Molecular Diagnosis and Environmental Effect in Chronic-Degenerative Diseases, National Autonomous University of Mexico (UNAM), Tlalnepantla, México;Search for other works by this author on:Srinivas Mummidi;Srinivas MummididSouth Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Edinburg, TX, USA;Search for other works by this author on:Ravindranth Duggirala;Ravindranth DuggiraladSouth Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Edinburg, TX, USA;Search for other works by this author on:Juan C. López-Alvarenga;Juan C. López-AlvarengadSouth Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Edinburg, TX, USA;eUniversidad Mexico Americana del Norte, Reynosa Tamaulipas, MéxicoSearch for other works by this author on:Monserrat Pérez-NavarroMonserrat Pérez-NavarroaDepartment of Nephrology, Hospital General de México, México City,Search for other works by this author on:
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135 - 146: Treatment of Hyperuricemia in Chronic Kidney DiseaseByJuan C. Ramirez-Sandoval;Juan C. Ramirez-SandovalaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, National Institute of Medical Sciences and Nutrition Salvador Zubirán (INCMNSZ), andSearch for other works by this author on:Magdalena MaderoMagdalena MaderobInstituto Nacional de Cardiología Ignacio Chávez, National Heart Institute, Mexico City, MexicoSearch for other works by this author on: