Podocytopathy
The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
Download citation file:
Digital Version
Print Version
Table of Contents
-
1 - 11: Cell Biology of the PodocyteByJ. Ashley Jefferson;J. Ashley JeffersonDepartment of Medicine, University of Washington, Seattle, Wash., USASearch for other works by this author on:Stuart J. ShanklandStuart J. ShanklandDepartment of Medicine, University of Washington, Seattle, Wash., USASearch for other works by this author on:
-
12 - 21: Cell Cycle and Podocyte InjuryByHenning Hagmann;Henning HagmannaDepartment II of Internal Medicine and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany;Search for other works by this author on:Stuart J. Shankland;Stuart J. ShanklandbDivision of Nephrology, University of Washington, Seattle, Wash., USASearch for other works by this author on:Paul T. BrinkkoetterPaul T. BrinkkoetteraDepartment II of Internal Medicine and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany;Search for other works by this author on:
-
22 - 53: The Podocyte Cytoskeleton: Key to a Functioning Glomerulus in Health and DiseaseByChristian FaulChristian FaulDivision of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:
-
54 - 63: Crosstalk between Podocytes and Tubular Epithelial CellsByJoseph C.K. Leung;Joseph C.K. LeungaDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, andSearch for other works by this author on:Kar Neng Lai;Kar Neng LaibNephrology Center, Hong Kong Sanatorium and Hospital, Hong Kong, SAR, ChinaSearch for other works by this author on:Sydney C.W. TangSydney C.W. TangaDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, andSearch for other works by this author on:
-
64 - 82: Role of Mitochondria in Podocyte InjuryByYanggang Yuan;Yanggang YuanaDepartment of Nephrology, The First Affiliated Hospital of Nanjing Medical University,Search for other works by this author on:Songming Huang;Songming HuangbDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University, andcInstitute of Pediatrics, Nanjing Medical University, Nanjing, PR ChinaSearch for other works by this author on:Aihua ZhangAihua ZhangbDepartment of Nephrology, Nanjing Children's Hospital, Affiliated to Nanjing Medical University, andcInstitute of Pediatrics, Nanjing Medical University, Nanjing, PR ChinaSearch for other works by this author on:
-
83 - 100: Autophagy in PodocytesByLei Zhang;Lei ZhangaDepartment of Nephrology, Second Xiangya Hospital, Central South University, Changsha, PR China;bDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Georgia Regents University and Charlie Norwood VA Medical Center, Augusta, Ga., USASearch for other works by this author on:Man J. Livingston;Man J. LivingstonbDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Georgia Regents University and Charlie Norwood VA Medical Center, Augusta, Ga., USASearch for other works by this author on:Jian-Kang Chen;Jian-Kang ChenbDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Georgia Regents University and Charlie Norwood VA Medical Center, Augusta, Ga., USASearch for other works by this author on:Zheng DongZheng DongaDepartment of Nephrology, Second Xiangya Hospital, Central South University, Changsha, PR China;bDepartment of Cellular Biology and Anatomy, Medical College of Georgia at Georgia Regents University and Charlie Norwood VA Medical Center, Augusta, Ga., USASearch for other works by this author on:
-
101 - 111: PPAR-γ Signaling in Podocyte InjuryByWeidong Wang;Weidong WangaInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, PR China;Search for other works by this author on:Tianxin YangTianxin YangaInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, PR China;bDepartment of Internal Medicine, University of Utah and Veterans Affairs Medical Center, Salt Lake City, Utah, USASearch for other works by this author on:
-
112 - 121: Podocyte Injury in FSGSByWen Yi Ding;Wen Yi DingAcademic Renal Unit, University of Bristol, Bristol, UKSearch for other works by this author on:Moin A. SaleemMoin A. SaleemAcademic Renal Unit, University of Bristol, Bristol, UKSearch for other works by this author on:
-
122 - 131: Circulating Soluble Urokinase Receptor and Focal Segmental GlomerulosclerosisByChangli Wei;Changli WeiDepartment of Internal Medicine, Rush University, Chicago, Ill., USASearch for other works by this author on:Jochen ReiserJochen ReiserDepartment of Internal Medicine, Rush University, Chicago, Ill., USASearch for other works by this author on:
-
132 - 144: Anti-Phospholipase A2 Receptor-1 Autoantibodies and Membranous NephropathyByLaurence H. BeckLaurence H. BeckBoston University School of Medicine, Boston, Mass., USASearch for other works by this author on:
-
145 - 156: Anti-Neutral Endopeptidase Antibodies, Autoantibodies, Anti-Bovine Serum Albumin Antibodies and Membranous NephropathyByP. Ronco;P. RoncoaINSERM UMR S 1155,bSorbonne Universités, UPMC Univ Paris 06, andcAP-HP, Hôpital Tenon, Service de Néphrologie et Dialyses, Paris, FranceSearch for other works by this author on:H. DebiecH. DebiecaINSERM UMR S 1155,bSorbonne Universités, UPMC Univ Paris 06, andcAP-HP, Hôpital Tenon, Service de Néphrologie et Dialyses, Paris, FranceSearch for other works by this author on:
-
157 - 173: Podocytopathy in Diabetes: A Metabolic DisorderBySandra Merscher;Sandra MerscheraDivision of Nephrology and Hypertension, Department of Medicine andbDiabetes Research Institute, andcPeggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:Oliver Lenz;Oliver LenzaDivision of Nephrology and Hypertension, Department of Medicine andSearch for other works by this author on:Alessia FornoniAlessia FornoniaDivision of Nephrology and Hypertension, Department of Medicine andbDiabetes Research Institute, andcPeggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Fla., USASearch for other works by this author on:
-
174 - 180: Obesity-Related Glomerulopathy and Podocyte InjuryByMarcello CamiciMarcello CamiciUniversity Hospitals, Pisa, ItalySearch for other works by this author on:
-
181 - 190: Podocyte Injury in HIV-Associated NephropathyBySandeep K. Mallipattu;Sandeep K. MallipattuaDivision of Nephrology, Department of Medicine, Stony Brook University School of Medicine,Search for other works by this author on:John C. HeJohn C. HebDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, andcRenal Section, James J. Peters VA Medical Center, New York, N.Y., USASearch for other works by this author on:
-
191 - 198: Retinoic Acid: A Potential Pharmacologic Approach in the Treatment of PodocytopathyByShuchita Sharma;Shuchita SharmaaDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai,Search for other works by this author on:Sandeep K. Mallipattu;Sandeep K. MallipattubDivision of Nephrology, Department of Medicine, Stony Brook University School of Medicine, andSearch for other works by this author on:Yifei Zhong;Yifei ZhongdDepartment of Nephrology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, PR ChinaSearch for other works by this author on:John C. HeJohn C. HeaDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai,cRenal Division, James J. Peters VA Medical Center, New York, N.Y., USA;Search for other works by this author on:
-
199 - 206: Immunomodulatory Drugs and the PodocyteByPeter W. MathiesonPeter W. MathiesonFaculty of Medicine and Dentistry, University of Bristol, and North Bristol NHS Trust, Bristol, UKSearch for other works by this author on:
-
207 - 214: Triptolide Protects Podocytes from InjuryByWeisong Qin;Weisong QinNational Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR ChinaSearch for other works by this author on:Zhi-Hong LiuZhi-Hong LiuNational Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR ChinaSearch for other works by this author on:
-
215 - 223: Fly: A Model to Study the PodocyteByJianbo Na;Jianbo NaDepartment of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, N.Y., USASearch for other works by this author on:Ross L. CaganRoss L. CaganDepartment of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, N.Y., USASearch for other works by this author on:
-
224 - 234: Zebrafish Models of PodocytopathiesByRudrick C. Boucher;Rudrick C. BoucherDepartments of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Mich., USASearch for other works by this author on:Weibin ZhouWeibin ZhouDepartments of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Mich., USASearch for other works by this author on:
-
235 - 244: The Role of MicroRNAs in PodocytesByShaolin Shi;Shaolin ShiNational Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR ChinaSearch for other works by this author on:Zhi-Hong LiuZhi-Hong LiuNational Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, PR ChinaSearch for other works by this author on:
-
245 - 255: An Integrative Biology Approach to Study Podocyte FunctionByWenjun Ju;Wenjun JuaDepartments of Internal Medicine,bComputational Medicine and Bioinformatics, andSearch for other works by this author on:Jeffery B. Hodgin;Jeffery B. HodgincPathology, University of Michigan, Ann Arbor, Mich., USA;Search for other works by this author on:Song Jiang;Song JiangdNational Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, ChinaSearch for other works by this author on:Matthias KretzlerMatthias KretzleraDepartments of Internal Medicine,bComputational Medicine and Bioinformatics, andSearch for other works by this author on: