Intracranial Gliomas Part II - Adjuvant TherapyAvailable to Purchase
Treatment of patients with intracranial gliomas, especially high-grade neoplasms, usually requires postoperative adjuvant therapy. Significant progress in the understanding of tumor biology, technological advances in irradiation delivery, and development of novel antitumor drugs have led to an expansion of the therapeutic arsenal in neuro-oncology. This publication provides a unique review of the various options for adjuvant therapy. Special emphasis is on current evidence-based treatment standards and guidelines, and on perspectives of further improvement in long-term outcomes. Chapters review the histopathological and molecular features of gliomas and describe basic principles and clinical results of fractionated radiotherapy, stereotactic radiosurgery, brachytherapy, use of radiosensitizers, systemic chemotherapy and antiangiogenic therapy. Particular attention is paid to treatment of pediatric patients and to physical and psychological rehabilitation and supportive care at the end of life. This book and its accompanying volumes are mainly directed at neuro-oncologists, radiation oncologists, and other clinicians treating patients with brain tumors.
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Table of Contents
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1 - 37: Pathology and Genetics of GliomasByTakashi Komori;Takashi KomoriaDepartment of Laboratory Medicine and Pathology (Neuropathology), Tokyo Metropolitan Neurological Hospital, andSearch for other works by this author on:Yoshihiro Muragaki;Yoshihiro MuragakibFaculty of Advanced Techno-Surgery andcDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo, JapanSearch for other works by this author on:Mikhail F. ChernovMikhail F. ChernovbFaculty of Advanced Techno-Surgery andcDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo, JapanSearch for other works by this author on:
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38 - 47: Fractionated Radiotherapy of Intracranial GliomasByAmol J. GhiaAmol J. GhiaDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USASearch for other works by this author on:
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48 - 61: Stereotactic Radiosurgery in the Multimodality Management of Residual or Recurrent Glioblastoma MultiformeByAjay Niranjan;Ajay NiranjanaDepartments of Neurological Surgery andcCenter for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USASearch for other works by this author on:Edward A. Monaco;Edward A. MonacoaDepartments of Neurological Surgery andcCenter for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USASearch for other works by this author on:Hideyuki Kano;Hideyuki KanoaDepartments of Neurological Surgery andcCenter for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USASearch for other works by this author on:John C. Flickinger;John C. FlickingeraDepartments of Neurological Surgery andbRadiation Oncology, andcCenter for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USASearch for other works by this author on:L. Dade LunsfordL. Dade LunsfordaDepartments of Neurological Surgery andbRadiation Oncology, andcCenter for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USASearch for other works by this author on:
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62 - 71: Stereotactic Radiosurgery of Intracranial Low-Grade GliomasByJeremy C. GanzJeremy C. GanzRetired Neurosurgeon, Ulverston, UKSearch for other works by this author on:
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72 - 86: Brachytherapy of Intracranial GliomasBySilke Birgit Nachbichler;Silke Birgit NachbichleraDepartments of Radiation Oncology andSearch for other works by this author on:Friedrich-Wilhelm KrethFriedrich-Wilhelm KrethbNeurosurgery, Ludwig-Maximilians-University (LMU) Hospital, Munich, GermanySearch for other works by this author on:
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87 - 101: Irradiation of Intracranial Gliomas in ChildrenByRolf-Dieter Kortmann;Rolf-Dieter KortmannaDepartments of Radiation Therapy andSearch for other works by this author on:Clemens Seidel;Clemens SeidelaDepartments of Radiation Therapy andSearch for other works by this author on:Klaus Müller;Klaus MülleraDepartments of Radiation Therapy andSearch for other works by this author on:Franz Wolfgang HirschFranz Wolfgang HirschbPediatric Radiology, University Hospital Leipzig, Leipzig, GermanySearch for other works by this author on:
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102 - 115: Role of Radiosensitizers in Radiation Treatment of GliomasByRandi J. Cohen;Randi J. CohenUniversity of Maryland, Baltimore, MD, USASearch for other works by this author on:Minesh P. MehtaMinesh P. MehtaUniversity of Maryland, Baltimore, MD, USASearch for other works by this author on:
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116 - 144: Chemotherapy of High-Grade Astrocytomas in AdultsByVinay K. Puduvalli;Vinay K. PuduvalliaDivision of Neuro-Oncology andSearch for other works by this author on:Nguyen HoangNguyen HoangbDepartment of Neurosurgery, The Ohio State University Comprehensive Cancer Center, Columbus, OH, USASearch for other works by this author on:
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145 - 151: Chemotherapy of Diffuse Astrocytoma (WHO grade II) in AdultsByYoshitaka NaritaYoshitaka NaritaDepartment of Neurosurgery and Neuro-oncology, National Cancer Center, Tokyo, JapanSearch for other works by this author on:
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152 - 161: Chemotherapy of OligodendrogliomasByJan Drappatz;Jan DrappatzDepartment of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for other works by this author on:Frank LiebermanFrank LiebermanDepartment of Neurology, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for other works by this author on:
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162 - 167: Chemotherapy of Intracranial Gliomas in ChildrenByKeita TerashimaKeita TerashimaDivision of Neuro-Oncology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, JapanSearch for other works by this author on:
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168 - 179: Perspectives of Personalized Chemotherapy of Gliomas Based on Molecular Tumor ProfilingByRiccardo Soffietti;Riccardo SoffiettiDepartment of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, ItalySearch for other works by this author on:Federica Franchino;Federica FranchinoDepartment of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, ItalySearch for other works by this author on:Michela Magistrello;Michela MagistrelloDepartment of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, ItalySearch for other works by this author on:Alessia Pellerino;Alessia PellerinoDepartment of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, ItalySearch for other works by this author on:Roberta RudàRoberta RudàDepartment of Neuro-Oncology, University of Turin and City of Health and Science Hospital, Turin, ItalySearch for other works by this author on:
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180 - 199: Antiangiogenic Therapy of High-Grade GliomasByJasmin Jo;Jasmin JoCenter for Neuro-Oncology, Dana-Farber Cancer Institute, and Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USASearch for other works by this author on:Patrick Y. WenPatrick Y. WenCenter for Neuro-Oncology, Dana-Farber Cancer Institute, and Division of Neuro-Oncology, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USASearch for other works by this author on:
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200 - 209: Search for More Effective Chemotherapeutic Regimens for Gliomas: Challenges and HopesByJethro Hu;Jethro HuaCedars-Sinai Medical Center, Los Angeles, CA; andSearch for other works by this author on:Santosh KesariSantosh KesaribDepartment of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute, andcDepartment of Neuro-Oncology, Pacific Neuroscience Institute at Providence Saint John's Health Center, Santa Monica, CA, USASearch for other works by this author on:
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210 - 228: Physical and Psychological Rehabilitation of Patients with Intracranial GliomaByJulija Andrejeva;Julija AndrejevaaDepartment of Rehabilitation, Faculty of Health Sciences, Klaipeda University, Klaipeda, Lithuania; andSearch for other works by this author on:Olesya V. VolkovaOlesya V. VolkovabDepartment of Clinical Psychology and Psychotherapy, Krasnoyarsk State Medical University Named after Professor V.F. Voyno-Yasenetsky, Krasnoyarsk, RussiaSearch for other works by this author on:
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229 - 237: Palliative and Supportive Care of Patients with Intracranial GliomaByAndrea Pace;Andrea PaceNeuro-Oncology Unit, Regina Elena National Cancer Institute, Rome, ItalySearch for other works by this author on:Veronica VillaniVeronica VillaniNeuro-Oncology Unit, Regina Elena National Cancer Institute, Rome, ItalySearch for other works by this author on: