Acute Kidney Injury - Basic Research and Clinical Practice
Acute Kidney Injury (AKI) is a complex syndrome that is prevalent among hospitalized patients. In recent years, occurrence of AKI events has risen due to a growing susceptibility of fragile and elderly subjects and an increase in the use of complex procedures such as cardiovascular surgery and imaging techniques. Exposure to potentially nephrotoxic drugs, such as new chemotherapeutic agents, is also proving to be a cause of AKI. This book summarizes recent advances in various settings. A reappraisal of current definitions and staging classifications for AKI in the literature is followed by a description of new criteria for identifying patients at risk and characterizing early kidney damage by using biomarkers. Other important topics include the sequelae of AKI and AKI in special populations such as children, the elderly, and those with cancer. The effects of AKI and its consequences on healthcare expenditures are also addressed from several perspectives. AKI management requires the cooperation of different specialists to optimize outcomes. This book is thus a perfect tool not only for nephrologists, but for every specialist involved in the complicated endeavor of improving patient care.
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1 - 12: Acute Kidney Injury: Diagnosis and Classification in Adults and ChildrenByZaccaria Ricci;Zaccaria RicciaDepartment of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, andSearch for other works by this author on:Stefano RomagnoliStefano RomagnolibDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero-Universitaria Careggi, Florence, ItalySearch for other works by this author on:
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13 - 20: Acute Kidney Injury Risk AssessmentByWuhua Jiang;Wuhua JiangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jiarui Xu;Jiarui XuaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Bo Shen;Bo ShenaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Yimei Wang;Yimei WangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jie Teng;Jie TengaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Xiaoqiang DingXiaoqiang DingaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:
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21 - 34: Acute Kidney Injury Biomarkers: What Do They Tell Us?ByRishabh Singh;Rishabh SinghaRoyal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey,bMinimal Access Therapy Training Unit, Post Graduate Medical School, University of Surrey, Manor Park, Guildford, Surrey,Search for other works by this author on:Joanna Dodkins;Joanna DodkinsaRoyal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey,cDepartment of Intensive Care Medicine and Surrey Peri-Operative Anaesthesia and Critical Care Collaborative Research Group, Guildford, Surrey,Search for other works by this author on:James F. Doyle;James F. DoylecDepartment of Intensive Care Medicine and Surrey Peri-Operative Anaesthesia and Critical Care Collaborative Research Group, Guildford, Surrey,dDepartment of Intensive Care Medicine, Royal Brompton and Harefield NHS Foundation Trust, London, andSearch for other works by this author on:Lui G. ForniLui G. ForniaRoyal Surrey County Hospital NHS Foundation Trust, Guildford, Surrey,cDepartment of Intensive Care Medicine and Surrey Peri-Operative Anaesthesia and Critical Care Collaborative Research Group, Guildford, Surrey,eDepartment of Clinical and Experimental Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UKSearch for other works by this author on:
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35 - 44: Acute Kidney Injury RecoveryByCarlos E. Palant;Carlos E. PalantGeorge Washington University Medical Center, and Washington DC Veterans Affairs Medical Center, Washington, DC, USASearch for other works by this author on:Samir S. Patel;Samir S. PatelGeorge Washington University Medical Center, and Washington DC Veterans Affairs Medical Center, Washington, DC, USASearch for other works by this author on:Lakhmir S. ChawlaLakhmir S. ChawlaGeorge Washington University Medical Center, and Washington DC Veterans Affairs Medical Center, Washington, DC, USASearch for other works by this author on:
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45 - 54: Acute Kidney Injury to Chronic Kidney Disease TransitionByMarco Fiorentino;Marco FiorentinoaDepartment of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, andcThe Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USASearch for other works by this author on:Giuseppe Grandaliano;Giuseppe GrandalianobNephrology, Dialysis and Transplantation Unit, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy;Search for other works by this author on:Loreto Gesualdo;Loreto GesualdoaDepartment of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, andSearch for other works by this author on:Giuseppe CastellanoGiuseppe CastellanoaDepartment of Emergency and Organ Transplantation, Nephrology, Dialysis and Transplantation Unit, University of Bari, Bari, andSearch for other works by this author on:
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55 - 67: Acute Kidney Injury and Big DataByScott M. Sutherland;Scott M. SutherlandaDepartment of Pediatrics, Division of Nephrology, Stanford University, Stanford, CA, andSearch for other works by this author on:Stuart L. Goldstein;Stuart L. GoldsteinbDepartment of Pediatrics, Division of Pediatric Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA;Search for other works by this author on:Sean M. BagshawSean M. BagshawcDepartment of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, CanadaSearch for other works by this author on:
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68 - 80: Quality Measures in Acute Kidney Injury ManagementByBo Shen;Bo ShenaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jiarui Xu;Jiarui XuaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Yimei Wang;Yimei WangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Wuhua Jiang;Wuhua JiangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Zhen Zhang;Zhen ZhangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jiawei Yu;Jiawei YuaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jianzhou Zou;Jianzhou ZouaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jie Teng;Jie TengaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Xiaoqiang DingXiaoqiang DingaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center for Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification,eHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:
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81 - 88: Acute Kidney Injury and Information TechnologyByMira Küllmar;Mira KüllmarDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, GermanySearch for other works by this author on:Alexander ZarbockAlexander ZarbockDepartment of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, GermanySearch for other works by this author on:
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89 - 99: Technology in Medicine: Moving Towards Precision Management of Acute Kidney InjuryByJorge Cerdá;Jorge CerdáaDivision of Nephrology, Department of Medicine, Albany Medical College, Albany, NY, USA;Search for other works by this author on:Gianluca Villa;Gianluca VillabDepartment of Health Science, Section of Anesthesiology and Intensive Care, University of Florence, Florence,cInternational Renal Research Institute of Vicenza (IRRIV),Search for other works by this author on:Mauro Neri;Mauro NericInternational Renal Research Institute of Vicenza (IRRIV),dDepartment of Nephrology Dialysis and Transplantation, San Bortolo Hospital, andeDepartment of Management and Engineering, Università degli Studi di Padova, Vicenza, ItalySearch for other works by this author on:Claudio RoncoClaudio RoncocInternational Renal Research Institute of Vicenza (IRRIV),dDepartment of Nephrology Dialysis and Transplantation, San Bortolo Hospital, andSearch for other works by this author on:
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100 - 112: The Burden of Acute Kidney Injury and Related Financial IssuesByMarlies Ostermann;Marlies OstermannaDepartment of Critical Care, King's College London, Guy's and St Thomas' NHS Foundation Hospital, London, UK;Search for other works by this author on:Jorge CerdáJorge CerdábDivision of Nephrology, Department of Medicine, Albany Medical College, Albany, NY, USASearch for other works by this author on:
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113 - 126: Pediatric Acute Kidney InjuryByTiziana Fragasso;Tiziana FragassoaDepartment of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy;Search for other works by this author on:Zaccaria Ricci;Zaccaria RicciaDepartment of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy;Search for other works by this author on:Stuart L. GoldsteinStuart L. GoldsteinbCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USASearch for other works by this author on:
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127 - 136: Acute Kidney Injury in Cardiac SurgeryByJiarui Xu;Jiarui XuaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Wuhua Jiang;Wuhua JiangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Bo Shen;Bo ShenaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Yi Fang;Yi FangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Jie Teng;Jie TengaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Yimei Wang;Yimei WangaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:Xiaoqiang DingXiaoqiang DingaDepartment of Nephrology, Zhongshan Hospital, Fudan University,bShanghai Medical Center of Kidney Disease,cShanghai Institute of Kidney and Dialysis,dShanghai Key Laboratory of Kidney and Blood Purification, andeHemodialysis Quality Control Center of Shanghai, Shanghai, ChinaSearch for other works by this author on:
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137 - 148: Acute Kidney Injury in Cancer PatientsByMaurizio Gallieni;Maurizio GallieniaNephrology and Dialysis Unit, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan,bDepartment of Clinical and Biomedical Sciences “Luigi Sacco,” University of Milan, Milan, andSearch for other works by this author on:Laura Cosmai;Laura CosmaiaNephrology and Dialysis Unit, San Carlo Borromeo Hospital, ASST Santi Paolo e Carlo, Milan,Search for other works by this author on:Camillo PortaCamillo PortacMedical Oncology, I.R.C.C.S. San Matteo University Hospital Foundation, Pavia, ItalySearch for other works by this author on:
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149 - 160: Acute Kidney Injury in the Geriatric PopulationByMitchell H. Rosner;Mitchell H. RosneraDivision of Nephrology, University of Virginia Health System, Charlottesville, VA, USA;Search for other works by this author on:Gaetano La Manna;Gaetano La MannabNephrology, Dialysis and Renal Transplantation Unit, S. Orsola University Hospital, Bologna,Search for other works by this author on:Claudio RoncoClaudio RoncocDepartment of Nephrology Dialysis and Transplantation, San Bortolo Hospital anddInternational Renal Research Institute of Vicenza (IRRIV), Vicenza, ItalySearch for other works by this author on: