ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes
Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk. Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.
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1 - 4: Acute Dialysis Quality Initiative (ADQI)ByClaudio Ronco;Claudio RoncoaDepartment of Nephrology Dialysis and Transplantation & International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:John A. Kellum;John A. KellumbClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Rinaldo Bellomo;Rinaldo BellomocDepartment of Intensive Care, Austin Hospital, Heidelberg, Vic., Australia;Search for other works by this author on:Ravindra L. MehtaRavindra L. MehtadDivision of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, Calif., USASearch for other works by this author on:
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5 - 12: Implementation of Novel Biomarkers in the Diagnosis, Prognosis, and Management of Acute Kidney Injury: Executive Summary from the Tenth Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByPeter A. McCullough;Peter A. McCullough1St. John Providence Health System, Warren, Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USA;Search for other works by this author on:Josee Bouchard;Josee Bouchard2Division of Nephrology and Hypertension, Division of Nephrology, Université de Montréal, Montréal, Que., Canada;Search for other works by this author on:Sushrut S. Waikar;Sushrut S. Waikar3Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass., USA;Search for other works by this author on:Edward D. Siew;Edward D. Siew4Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn., USA;Search for other works by this author on:Zoltan H. Endre;Zoltan H. Endre5Christchurch Kidney Research Group, Department of Medicine, University of Otago, Christchurch, New Zealand;Search for other works by this author on:Stuart L. Goldstein;Stuart L. Goldstein6Center for Acute Care Nephrology, Division of Nephrology and Hypertension, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA;Search for other works by this author on:Jay L. Koyner;Jay L. Koyner7Section of Nephrology, Department of Medicine, University of Chicago, Pritzker School of Medicine, Chicago, Ill., USA;Search for other works by this author on:Etienne Macedo;Etienne Macedo8Division of Nephrology, University of São Paulo, São Paulo, Brazil;Search for other works by this author on:Kent Doi;Kent Doi9Department of Nephrology and Endocrinology, The University of Tokyo, Tokyo, Japan;Search for other works by this author on:Salvatore Di Somma;Salvatore Di Somma10Sant'Andrea Hospital, Second Faculty Medical School, La Sapienza University of Rome, Rome, Italy;Search for other works by this author on:Andrew Lewington;Andrew Lewington11Leeds Teaching Hospitals, Leeds, UK;Search for other works by this author on:Ravi Thadhani;Ravi Thadhani12Division of Nephrology, Massachusetts General Hospital, Boston, Mass., USA;Search for other works by this author on:Raj Chakravarthi;Raj Chakravarthi13Division of Nephrology, Albany Medical College, Albany, N.Y., USA;Search for other works by this author on:Can Ice;Can Ice14Department of Intensive Care Adults, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands;Search for other works by this author on:Mark D. Okusa;Mark D. Okusa15University of Virginia School of Medicine, Charlottesville, Va., USA;Search for other works by this author on:Jacques Duranteau;Jacques Duranteau16Nephrology Unit, Le Kremlin Bicetre, Bicetre, France;Search for other works by this author on:Peter Doran;Peter Doran17Medizinische Poliklinik, University of Munich, Munich, Germany;Search for other works by this author on:Li Yang;Li Yang18Renal Division, Brigham and Women's Hospital, Boston, Mass., USA;Search for other works by this author on:Bertrand L. Jaber;Bertrand L. Jaber19Division of Nephrology, Tufts Medical Center, Boston, Mass., USA;Search for other works by this author on:Shane Meehan;Shane Meehan20Department of Pathology, Section of Nephrology, University of Chicago, Chicago, Ill., USA;Search for other works by this author on:John A. Kellum;John A. Kellum21Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Michael Haase;Michael Haase22Department of Nephrology, Hypertension, Diabetes and Endocrinology, Otto von Guericke University, Magdeburg, Germany;Search for other works by this author on:Patrick T. Murray;Patrick T. Murray23School of Medicine and Medical Science, University College Dublin, Dublin, Ireland;Search for other works by this author on:Dinna Cruz;Dinna Cruz24Department of Nephrology Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Alan Maisel;Alan Maisel25Department of Medicine and Cardiology, San Diego VA Medical Center and University of California, San Diego, Calif., USA;Search for other works by this author on:Sean M. Bagshaw;Sean M. Bagshaw26Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada;Search for other works by this author on:Lakhmir S. Chawla;Lakhmir S. Chawla27Department of Anesthesiology and Critical Care Medicine and Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University Medical Center, Washington, D.C., USA;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. Mehta28Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Andrew D. Shaw;Andrew D. Shaw29Department of Anesthesiology, Duke University Medical Center, Durham, N.C., USA;Search for other works by this author on:Claudio Ronco;Claudio Ronco30Department of Nephrology, International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) Consensus Groupfor the Acute Dialysis Quality Initiative (ADQI) Consensus GroupSearch for other works by this author on:
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13 - 29: Diagnosis of Acute Kidney Injury Using Functional and Injury Biomarkers: Workgroup Statements from the Tenth Acute Dialysis Quality Initiative Consensus ConferenceByPeter A. McCullough;Peter A. McCulloughaSt. John Providence Health System, Detroit, Mich., USA;Search for other works by this author on:Andrew D. Shaw;Andrew D. ShawbDepartment of Anesthesiology, Duke University Medical Center, Durham, N.C., USA;Search for other works by this author on:Michael Haase;Michael HaasecDepartment of Nephrology, Hypertension, Diabetology and Endocrinology, Otto von Guericke University, Magdeburg, Germany;Search for other works by this author on:Josee Bouchard;Josee BoucharddDivision of Nephrology and Hypertension, Department of Medicine, University of Montreal, Montreal, Que., Canada;Search for other works by this author on:Sushrut S. Waikar;Sushrut S. WaikareDepartment of Medicine, Brigham and Womenʼs Hospital, Harvard Medical School, Boston, Mass., USA;Search for other works by this author on:Edward D. Siew;Edward D. SiewfDivision of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn., USA;Search for other works by this author on:Patrick T. Murray;Patrick T. MurraygDepartment of Medicine, University of Dublin, Dublin, Ireland;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. MehtahDepartment of Medicine, University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncoiDepartment of Nephrology Dialysis and Transplantation & International Renal Research Institute, St. Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:
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30 - 44: Differential Diagnosis of AKI in Clinical Practice by Functional and Damage Biomarkers: Workgroup Statements from the Tenth Acute Dialysis Quality Initiative Consensus ConferenceByZoltan H. Endre;Zoltan H. EndreaDepartment of Nephrology, Prince of Wales Clinical School, University of New South Wales, Sydney, N.S.W., Australia;bChristchurch Kidney Research Group, Department of Medicine, University of Otago, Christchurch, New Zealand;Search for other works by this author on:John A. Kellum;John A. KellumcDepartment of Critical Care Medicine, School of Medicine, Pittsburgh, Pa., USA;Search for other works by this author on:Salvatore Di Somma;Salvatore Di SommadDepartment of Medical and Surgery Sciences and Translational Medicine, University La Sapienza, Rome, Italy;Search for other works by this author on:Kent Doi;Kent DoieDepartment of Emergency and Critical Care Medicine, The University of Tokyo, Tokyo, Japan;Search for other works by this author on:Stuart L. Goldstein;Stuart L. GoldsteinfCenter for Acute Care Nephrology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA;Search for other works by this author on:Jay L. Koyner;Jay L. KoynergSection of Nephrology, Prizker Shool of Medicine, University of Chicago, Chicago, Ill., USA;Search for other works by this author on:Etienne Macedo;Etienne MacedohDepartment of Internal Medicine, Division of Nephrology, University of São Paulo School of Medicine, São Paulo, Brazil;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. MehtaiUCSD Medical Centre University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Patrick T. Murray;Patrick T. MurrayjSchool of Medicine and Medical Science, University College Dublin, Dublin, IrelandSearch for other works by this author on:
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45 - 64: Use of Biomarkers to Assess Prognosis and Guide Management of Patients with Acute Kidney InjuryByDinna N. Cruz;Dinna N. CruzaDepartment of Nephrology Dialysis & Transplantation, San Bortolo Hospital, Vicenza, Italy;bInternational Renal Research Institute (IRRIV), Vicenza, Italy;Search for other works by this author on:Sean M. Bagshaw;Sean M. BagshawcDivision of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada;Search for other works by this author on:Alan Maisel;Alan MaiseldDepartment of Medicine and Cardiology, San Diego VA Medical Center and University of California, San Diego, Calif., USA;Search for other works by this author on:Andrew Lewington;Andrew LewingtoneDepartment of Renal Medicine, St James's University Hospital, Leeds, UK;Search for other works by this author on:Ravi Thadhani;Ravi ThadhanifDivision of Nephrology, Massachusetts General Hospital and Harvard Medical School (RT), Boston, Mass., USA;Search for other works by this author on:Rajasekara Chakravarthi;Rajasekara ChakravarthigDepartment of Nephrology, CARE Hospital, The Institute of Medical Sciences, Hyderabad, India;Search for other works by this author on:Patrick T. Murray;Patrick T. MurrayhSchool of Medicine & Medical Science, University College Dublin, Dublin, Ireland;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. MehtaiDepartment of Medicine and Nephrology, University of California, San Diego, Calif., USA;Search for other works by this author on:Lakhmir S. Chawla;Lakhmir S. ChawlajDepartment of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, D.C., USASearch for other works by this author on:
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65 - 81: Physiological Biomarkers of Acute Kidney Injury: A Conceptual Approach to Improving OutcomesByMark D. Okusa;Mark D. OkusaaDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, Charlottesville, Va., USA;Search for other works by this author on:Bertrand L. Jaber;Bertrand L. JaberbKidney and Dialysis Research Laboratory, Division of Nephrology, Department of Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Mass., USA;Search for other works by this author on:Peter Doran;Peter DorancUCD Clinical Research Centre, UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland;Search for other works by this author on:Jacques Duranteau;Jacques DuranteaudHôpitaux de Paris, Hôpital Bicêtre, Département d'Anesthésie-Réanimation, Université Paris Sud XI, Le Kremlin-Bicêtre, France;Search for other works by this author on:Li Yang;Li YangeRenal Division, Peking University First Hospital, Beijing, China;Search for other works by this author on:Patrick T. Murray;Patrick T. MurrayfDepartment of Medicine, University College Dublin, Dublin, Ireland;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. MehtagDepartment of Medicine, University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Can Ince;Can IncehDepartment of Intensive Care Adults, Erasmus MC University Medical Centre, Rotterdam, The NetherlandsSearch for other works by this author on:
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82 - 98: Pathophysiology of the Cardiorenal Syndromes: Executive Summary from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByPeter A. McCullough;Peter A. McCulloughaSt. John Providence Health System, Warren, Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USA;Search for other works by this author on:John A. Kellum;John A. KellumbClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Michael Haase;Michael HaasecDepartment of Nephrology, Hypertension, Diabetes and Endocrinology, Otto von Guericke University, Magdeburg, Germany;Search for other works by this author on:Christian Müller;Christian MüllerdUniversity Hospital, Basel, Switzerland;Search for other works by this author on:Kevin Damman;Kevin DammaneDepartment of Cardiology, University Medical Center Groningen, Groningen, The Netherlands;Search for other works by this author on:Patrick T. Murray;Patrick T. MurrayfSchool of Medicine and Medical Science, University College Dublin, Dublin, Ireland;Search for other works by this author on:Dinna Cruz;Dinna CruzgDepartment of Nephrology Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Andrew A. House;Andrew A. HousehSchulich School of Medicine and Dentistry, University of Western Ontario Division of Nephrology, University Hospital, London, Ont., Canada;Search for other works by this author on:Kai M. Schmidt-Ott;Kai M. Schmidt-OttiExperimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Max Delbrück Center for Molecular Medicine, Berlin, Germany;Search for other works by this author on:Giorgio Vescovo;Giorgio VescovojDepartment of Internal Medicine, S. Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Sean M. Bagshaw;Sean M. BagshawkDivision of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada;Search for other works by this author on:Eric A. Hoste;Eric A. HostelDepartment of Intensive Care Medicine, Ghent University Hospital, Gent, Belgium;Search for other works by this author on:Carlos Briguori;Carlos BriguorimDepartment of Cardiology, Clinica Mediterranea, Naples, Italy;Search for other works by this author on:Branko Braam;Branko BraamnDepartment of Medicine/Division of Nephrology and Immunology, University of Alberta Hospital, Edmonton, Alta., Canada;Search for other works by this author on:Lakhmir S. Chawla;Lakhmir S. ChawlaoDepartment of Anesthesiology and Critical Care Medicine and Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University Medical Center, Washington, D.C., USA;Search for other works by this author on:Maria R. Costanzo;Maria R. CostanzopMidwest Heart Foundation, Edward Heart Hospital, Naperville, Ill., USA;Search for other works by this author on:James A. Tumlin;James A. TumlinqDepartment of Medicine, College of Medicine, University of Tennessee, Chattanooga, Tenn., USA;Search for other works by this author on:Charles A. Herzog;Charles A. HerzogrHennepin County Medical Center, Minneapolis, Minn., USA;Search for other works by this author on:Ravindra L. Mehta;Ravindra L. MehtasDivision of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Hamid Rabb;Hamid RabbtNephrology Division, Johns Hopkins Hospital and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Md., USA;Search for other works by this author on:Andrew D. Shaw;Andrew D. ShawuDepartment of Anesthesiology, Duke University Medical Center, Durham, N.C., USA;Search for other works by this author on:Kai Singbartl;Kai SingbartlvDepartment of Critical Care Medicine, Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncowDepartment of Nephrology, International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) Consensus Groupfor the Acute Dialysis Quality Initiative (ADQI) Consensus GroupSearch for other works by this author on:
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99 - 116: Pathogenesis of Cardiorenal Syndrome Type 1 in Acute Decompensated Heart Failure: Workgroup Statements from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByMichael Haase;Michael HaaseaDepartment of Nephrology and Hypertension, Diabetes and Endocrinology, Otto von Guericke University Magdeburg, Magdeburg, Germany;Search for other works by this author on:Christian Müller;Christian MüllerbDepartment of Cardiology, University Hospital, Basel, Switzerland;Search for other works by this author on:Kevin Damman;Kevin DammancDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;Search for other works by this author on:Patrick T. Murray;Patrick T. MurraydNephrology and Clinical Pharmacology, University College Dublin School of Medicine and Medical Science, Dublin, Ireland;Search for other works by this author on:John A. Kellum;John A. KellumeClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncofDepartment of Nephrology, International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Peter A. McCullough;Peter A. McCulloughgSt. John Providence Health System, Warren, Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USASearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) Consensus Groupfor the Acute Dialysis Quality Initiative (ADQI) Consensus GroupSearch for other works by this author on:
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117 - 136: Pathophysiology of Cardiorenal Syndrome Type 2 in Stable Chronic Heart Failure: Workgroup Statements from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByDinna N. Cruz;Dinna N. CruzaDivision of Nephrology-Hypertension, Department of Medicine, University of California, San Diego, San Diego, Calif., USA;Search for other works by this author on:Kai M. Schmidt-Ott;Kai M. Schmidt-OttbDivision of Nephrology, London Health Sciences Centre, London, Ont., Canada;Search for other works by this author on:Giorgio Vescovo;Giorgio VescovocDepartment of Nephrology, Experimental and Clinical Research Center, Charité - Universitätsmedizin Berlin, and Max Delbrück Center for Molecular Medicine, Berlin, Germany;Search for other works by this author on:Andrew A. House;Andrew A. HousedDepartment of Internal Medicine, St. Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:John A. Kellum;John A. KellumeClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncofDepartment of Nephrology, International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Peter A. McCullough;Peter A. McCulloughgSt. John Providence Health System, Warren Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USASearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) Consensus Groupfor the Acute Dialysis Quality Initiative (ADQI) Consensus GroupSearch for other works by this author on:
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137 - 157: Cardiorenal Syndrome Type 3: Pathophysiologic and Epidemiologic ConsiderationsBySean M. Bagshaw;Sean M. BagshawaDivision of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada;Search for other works by this author on:Eric A. Hoste;Eric A. HostebDepartment of Critical Care Medicine, University of Gent, Gent, Belgium;Search for other works by this author on:Branko Braam;Branko BraamcDivision of Nephrology, Departments of Medicine and Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alta., Canada;Search for other works by this author on:Carlo Briguori;Carlo BriguoridDepartment of Cardiology, Clinica Mediterranea, Naples, Italy;Search for other works by this author on:John A. Kellum;John A. KellumeClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Peter A. McCullough;Peter A. McCulloughfSt. John Providence Health System, Warren, Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncogDepartment of Nephrology Dialysis and Transplantation and International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:for the Acute Dialysis Quality Initiative 11 Working Groupfor the Acute Dialysis Quality Initiative 11 Working GroupSearch for other works by this author on:
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158 - 173: Cardiorenal Syndrome Type 4: Insights on Clinical Presentation and Pathophysiology from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByJames A. Tumlin;James A. TumlinaDepartment of Medicine, College of Medicine, University of Tennessee, Chattanooga, Tenn., USA;Search for other works by this author on:Maria R. Costanzo;Maria R. CostanzobMidwest Heart Foundation, Edward Heart Hospital, Naperville, Ill., USA;Search for other works by this author on:Lakhmir S. Chawla;Lakhmir S. ChawlacDepartment of Anesthesiology and Critical Care Medicine and Division of Renal Diseases and Hypertension, Department of Medicine, George Washington University Medical Center, Washington, D.C., USA;Search for other works by this author on:Charles A. Herzog;Charles A. HerzogdDepartment of Internal Medicine, Chronic Disease Research Group, Hennepin County Medical Center, University of Minnesota, Minneapolis, Minn., USA;Search for other works by this author on:John A. Kellum;John A. KellumeClinical Research, Investigation, and Systems Modeling of Acute Illness Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USA;Search for other works by this author on:Peter A. McCullough;Peter A. McCulloughfSt. John Providence Health System, Warren Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncogDepartment of Nephrology, Dialysis and Transplantation and International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, ItalySearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) 11 Consensus Groupfor the Acute Dialysis Quality Initiative (ADQI) 11 Consensus GroupSearch for other works by this author on:
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174 - 194: Cardiorenal Syndrome Type 5: Clinical Presentation, Pathophysiology and Management Strategies from the Eleventh Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)ByRavindra L. Mehta;Ravindra L. MehtaaDepartment of Medicine, University of California San Diego, San Diego, Calif., USA;Search for other works by this author on:Hamid Rabb;Hamid RabbbDepartment of Medicine, Johns Hopkins University, Baltimore, Md., USA;Search for other works by this author on:Andrew D. Shaw;Andrew D. ShawcDepartment of Anesthesiology, Duke University Medical Center, Durham, N.C., USA;Search for other works by this author on:Kai Singbartl;Kai SingbartldDepartment of Anesthesiology, Penn State College of Medicine, Milton S. Hershey Medical Center, Hershey, Pa., USA;Search for other works by this author on:Claudio Ronco;Claudio RoncoeDepartment of Nephrology, International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy;Search for other works by this author on:Peter A. McCullough;Peter A. McCulloughfSt. John Providence Health System, Warren, Mich., Providence Hospitals and Medical Centers, Southfield and Novi, Mich., St. John Macomb Oakland Center, Madison Heights, Mich., St. John Hospital and Medical Center, Detroit, Mich., USA;Search for other works by this author on:John A. Kellum;John A. KellumgClinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pa., USASearch for other works by this author on:for the Acute Dialysis Quality Initiative (ADQI) 11 Working Groupfor the Acute Dialysis Quality Initiative (ADQI) 11 Working GroupSearch for other works by this author on: