Disorders of Fluid and Electrolyte Metabolism: Focus on Hyponatremia
It is well known that acute, severe hyponatremia is a life-threatening situation. However, there is growing evidence that mild and chronic hyponatremia may also have negative consequences. Gait disturbances, attention deficits, falls and fractures, and bone loss have all been reported, with increased mortality in almost every disease state if the patient is hyponatremic. This book has been written by key opinion leaders in the field and covers a spectrum of crucial aspects of hyponatremia, including a historical perspective, physiology and pathophysiology of water homeostasis, epidemiology of hyponatremia, and clinical features. A detailed description of all available therapies has been incorporated, with a guide to a clinician’s approach to key therapeutic situations. Hyponatremia is a topic that encompasses all areas of medicine, so this book will be of interest to specialists such as endocrinologists, nephrologists and internists, but will also be a valuable resource for all clinicians who manage patients with hyponatremia.
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Table of Contents
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1 - 7: Historical Aspects of HyponatremiaByChris J. Thompson;Chris J. ThompsonaAcademic Department of Endocrinology, Beaumont Hospital/RCSI Medical School, Dublin, Ireland;Search for other works by this author on:Alessandro Peri;Alessandro PeribSodium Unit, Endocrinology, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, “Center for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies” (DENOThe), University of Florence, Careggi University Hospital, Florence, Italy;Search for other works by this author on:Joseph G. VerbalisJoseph G. VerbaliscDivision of Endocrinology and Metabolism, Georgetown University, Washington, DC, USASearch for other works by this author on:
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8 - 23: Physiology and Pathophysiology of Water HomeostasisByHelbert Rondon-Berrios;Helbert Rondon-BerriosaRenal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, andSearch for other works by this author on:Tomas BerlTomas BerlbDivision of Renal Diseases and Hypertension, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USASearch for other works by this author on:
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24 - 35: Etiology and Epidemiology of HyponatremiaByVolker BurstVolker BurstDepartment II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Cologne, FranceSearch for other works by this author on:
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36 - 48: Morbidity and Mortality of HyponatremiaByAlessandro PeriAlessandro PeriSodium Unit, Endocrinology, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, “Center for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies” (DENOThe), University of Florence, Careggi University Hospital, Florence, ItalySearch for other works by this author on:
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49 - 60: Hyponatremia Is Linked to Bone Loss, Osteoporosis, Fragility and Bone FracturesByJulianna Barsony;Julianna BarsonyGeorgetown University Medical Center, Division of Endocrinology and Metabolism, Washington, DC, USASearch for other works by this author on:Lauren Kleess;Lauren KleessGeorgetown University Medical Center, Division of Endocrinology and Metabolism, Washington, DC, USASearch for other works by this author on:Joseph G. VerbalisJoseph G. VerbalisGeorgetown University Medical Center, Division of Endocrinology and Metabolism, Washington, DC, USASearch for other works by this author on:
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61 - 79: Euvolemic Hyponatremia Secondary to the Syndrome of Inappropriate AntidiuresisByJoseph G. VerbalisJoseph G. VerbalisGeorgetown University School of Medicine, Washington, DC, USASearch for other works by this author on:
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80 - 92: Hyponatremia and Glucocorticoid DeficiencyByAoife Garrahy;Aoife GarrahyAcademic Department of Endocrinology, Beaumont Hospital/RCSI Medical School, Dublin, IrelandSearch for other works by this author on:Chris J. ThompsonChris J. ThompsonAcademic Department of Endocrinology, Beaumont Hospital/RCSI Medical School, Dublin, IrelandSearch for other works by this author on:
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93 - 103: Hypovolemic HyponatremiaByDinushika Mohottige;Dinushika MohottigeaDuke University Medical Center,Search for other works by this author on:Ruediger Wilhelm Lehrich;Ruediger Wilhelm LehrichbDuke University Medical Center, andSearch for other works by this author on:Arthur GreenbergArthur GreenbergcEmeritus, Division of Nephrology, Department of Medicine, Duke University Medical Center, Durham, NC, USASearch for other works by this author on:
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104 - 112: Hypervolemic Hyponatremia (Liver)ByElsa Solà;Elsa SolàLiver Unit, Hospital Clinic of Barcelona, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEReHD), Barcelona, SpainSearch for other works by this author on:Pere GinèsPere GinèsLiver Unit, Hospital Clinic of Barcelona, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEReHD), Barcelona, SpainSearch for other works by this author on:
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113 - 129: Hypervolemic Hyponatremia in Heart FailureByCarlos D. Davila;Carlos D. DavilaDivision of Cardiology and the CardioVascular Center, Tufts Medical Center, Boston, MA, USASearch for other works by this author on:James E. UdelsonJames E. UdelsonDivision of Cardiology and the CardioVascular Center, Tufts Medical Center, Boston, MA, USASearch for other works by this author on:
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130 - 142: Adverse Consequences of Overly-Rapid Correction of HyponatremiaByRichard H. SternsRichard H. SternsUniversity of Rochester School of Medicine and Dentistry, Rochester, NY, USASearch for other works by this author on:
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143 - 160: Hyponatremia in Neurosurgical PatientsByMark J. Hannon;Mark J. HannonAcademic Department of Endocrinology, Beaumont Hospital, RCSI Medical School, Dublin, IrelandSearch for other works by this author on:Christopher J. ThompsonChristopher J. ThompsonAcademic Department of Endocrinology, Beaumont Hospital, RCSI Medical School, Dublin, IrelandSearch for other works by this author on:
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161 - 166: Hyponatremia in Oncology PatientsByChristian GrohéChristian GrohéDepartment of Respiratory Diseases, Ev. Lungenklinik Berlin, Universitätsmedizin Charite, Berlin, GermanySearch for other works by this author on:
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167 - 177: Hyponatremia-Inducing DrugsByGeorge Liamis;George LiamisDepartment of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, GreeceSearch for other works by this author on:Efstathia Megapanou;Efstathia MegapanouDepartment of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, GreeceSearch for other works by this author on:Moses Elisaf;Moses ElisafDepartment of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, GreeceSearch for other works by this author on:Haralampos MilionisHaralampos MilionisDepartment of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, GreeceSearch for other works by this author on:
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178 - 189: Exercise-Associated HyponatremiaByTamara Hew-ButlerTamara Hew-ButlerWayne State University, Detroit, MI, USASearch for other works by this author on:
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190 - 199: The Diagnostic Approach to the Patient with Hyponatremia: Are the Correct Investigations Being Done?ByPloutarchos Tzoulis;Ploutarchos TzoulisaCentre for Neuroendocrinology, Royal Free Campus, University College London Medical School, London, UK,Search for other works by this author on:Isabelle Runkle-De la VegaIsabelle Runkle-De la VegabDepartment of Endocrinology, Metabolism and Nutrition, Instituto de Investigación Sanitaria San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, SpainSearch for other works by this author on:
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200 - 203: Future of Hyponatremia ResearchByJoseph G. Verbalis;Joseph G. VerbalisaDivision of Endocrinology and Metabolism, Georgetown University, Washington, DC, USA;Search for other works by this author on:Alessandro Peri;Alessandro PeribSodium Unit, Endocrinology, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, “Center for Research, Transfer and High Education on Chronic, Inflammatory, Degenerative and Neoplastic Disorders for the Development of Novel Therapies” (DENOThe), University of Florence, Careggi University Hospital, Florence, Italy;Search for other works by this author on:Chris J. ThompsonChris J. ThompsoncAcademic Department of Endocrinology, Beaumont Hospital/ RCSI Medical School, Dublin, IrelandSearch for other works by this author on: