Hyperandrogenism in Women: Beyond Polycystic Ovary Syndrome
Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed.
The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors.
This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.
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Table of Contents
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1 - 17: In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome?ByDavid H. Abbott;David H. AbbottaWisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USAbDepartment of Obstetrics and Gynecology, University of Wisconsin, Madison, Wisconsin, USAdEndocrinology-Reproductive Physiology Training Program, University of Wisconsin, Madison, Wisconsin, USASearch for other works by this author on:Marissa Kraynak;Marissa KraynakaWisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USAdEndocrinology-Reproductive Physiology Training Program, University of Wisconsin, Madison, Wisconsin, USASearch for other works by this author on:Daniel A. Dumesic;Daniel A. DumesiceDepartment of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USASearch for other works by this author on:Jon E. LevineJon E. LevineaWisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USAcDepartment of Neuroscience, University of Wisconsin, Madison, Wisconsin, USAdEndocrinology-Reproductive Physiology Training Program, University of Wisconsin, Madison, Wisconsin, USASearch for other works by this author on:
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18 - 32: Androgens, Body Composition, and Their Metabolism Based on SexByVito Angelo Giagulli;Vito Angelo GiagulliaSection of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, Interdisciplinary Department of Medicine, University of Bari, School of Medicine, Policlinico, Bari, ItalySearch for other works by this author on:Marco Castellana;Marco CastellanabRutigliano, Bari, ItalySearch for other works by this author on:Carla Pelusi;Carla PelusicDivision of Endocrinology and Center for Applied Biomedical Research, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, ItalySearch for other works by this author on:Vincenzo TriggianiVincenzo TriggianiaSection of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, Interdisciplinary Department of Medicine, University of Bari, School of Medicine, Policlinico, Bari, ItalySearch for other works by this author on:
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33 - 49: Understanding the Role of Androgen Action in Female Adipose TissueByLina Schiffer;Lina SchifferaInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, United KingdomSearch for other works by this author on:Wiebke Arlt;Wiebke ArltaInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, United KingdombCentre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, University Hospitals Birmingham, NHS Foundation Trust, Edgbaston, Birmingham, United KingdomSearch for other works by this author on:Michael W. O’ReillyMichael W. O’ReillyaInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham, United KingdombCentre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, University Hospitals Birmingham, NHS Foundation Trust, Edgbaston, Birmingham, United KingdomSearch for other works by this author on:
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50 - 64: The Role of Androgen Excess on Insulin Sensitivity in WomenByEvanthia Diamanti-Kandarakis;Evanthia Diamanti-KandarakisDepartment of Endocrinology and Diabetes, YGEIA Hospital, Athens, GreeceSearch for other works by this author on:Olga Papalou;Olga PapalouDepartment of Endocrinology and Diabetes, YGEIA Hospital, Athens, GreeceSearch for other works by this author on:Eleni A. KandarakiEleni A. KandarakiDepartment of Endocrinology and Diabetes, YGEIA Hospital, Athens, GreeceSearch for other works by this author on:
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65 - 76: Androgens in Congenital Adrenal HyperplasiaByDuarte Pignatelli;Duarte PignatelliaInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, PortugalbInstitute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, PortugalcDepartment of Biomedicine, Faculty of Medicine of the University of Porto, Porto, PortugalSearch for other works by this author on:Sofia S. Pereira;Sofia S. PereiraaInstituto de Investigação e Inovação em Saúde (I3S), Universidade do Porto, Porto, PortugalbInstitute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, PortugaldEndocrine, Cardiovascular & Metabolic Research, Department of Anatomy, Multidisciplinary Unit for Biomedical Research (UMIB), ICBAS, University of Porto, Porto, PortugalSearch for other works by this author on:Renato PasqualiRenato PasqualieAlma Mater University of Bologna, Bologna, ItalySearch for other works by this author on:
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77 - 91: Androgens in Cushing’s SyndromeByGiorgio Arnaldi;Giorgio ArnaldiClinica di Endocrinologia e Malattie del Metabolismo, AOU Università Politecnica delle Marche, Ospedali Riuniti Ancona, Ancona, ItalySearch for other works by this author on:Marianna MartinoMarianna MartinoClinica di Endocrinologia e Malattie del Metabolismo, AOU Università Politecnica delle Marche, Ospedali Riuniti Ancona, Ancona, ItalySearch for other works by this author on:
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92 - 99: Hyperandrogenism and Adrenocortical TumorsByGuido Di DalmaziGuido Di DalmaziDivision of Endocrinology, Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, S. Orsola Malpighi Hospital, Bologna, ItalySearch for other works by this author on:
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100 - 107: Androgen-Secreting Ovarian TumorsByDjuro Macut;Djuro MacutaClinic of Endocrinology, Diabetes and Metabolic Diseases, Belgrade, SerbiadFaculty of Medicine, University of Belgrade, Belgrade, SerbiaSearch for other works by this author on:Dušan Ilić;Dušan IlićaClinic of Endocrinology, Diabetes and Metabolic Diseases, Belgrade, SerbiaSearch for other works by this author on:Ana Mitrović Jovanović;Ana Mitrović JovanovićbUniversity Clinic for Gynecology and Obstetrics “Narodni front”, Belgrade, SerbiadFaculty of Medicine, University of Belgrade, Belgrade, SerbiaSearch for other works by this author on:Jelica Bjekić-MacutJelica Bjekić-MacutcDepartment of Endocrinology, UMC Bežanijska kosa, Belgrade, SerbiadFaculty of Medicine, University of Belgrade, Belgrade, SerbiaSearch for other works by this author on:
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108 - 119: Endocrinology of Hirsutism: From Androgens to Androgen Excess DisordersByBulent Yilmaz;Bulent YilmazaDepartment of Obstetrics and Gynecology Health Science University, Tepecik Education and Research Hospital, Izmir, TurkeySearch for other works by this author on:Bulent Okan YildizBulent Okan YildizbDivision of Endocrinology and Metabolism, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, TurkeySearch for other works by this author on:
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120 - 134: Obesity and Androgens in WomenByRenato Pasquali;Renato PasqualiUniversity Alma Mater Studiorum of Bologna, Bologna, ItalySearch for other works by this author on:Claudia OrioloClaudia OrioloUniversity Alma Mater Studiorum of Bologna, Bologna, ItalySearch for other works by this author on:
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135 - 161: Androgens in Menopausal Women: Not Only Polycystic Ovary SyndromeByErvin K. Kostakis;Ervin K. KostakisaUnit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, GreeceSearch for other works by this author on:Lisonia N. Gkioni;Lisonia N. GkioniaUnit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, GreeceSearch for other works by this author on:Djuro Macut;Djuro MacutbClinic of Endocrinology, Diabetes and Metabolic Diseases, University of Belgrade, Belgrade, SerbiaSearch for other works by this author on:George MastorakosGeorge MastorakosaUnit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, GreeceSearch for other works by this author on:
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162 - 176: Androgen Excess in Women: Proteomic and Metabolomic ApproachesByMaría Insenser;María InsenserDiabetes Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal and Universidad de Alcalá, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, SpainSearch for other works by this author on:Héctor F. Escobar-MorrealeHéctor F. Escobar-MorrealeDiabetes Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal and Universidad de Alcalá, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, SpainSearch for other works by this author on:
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177 - 186: Androgens and Severe Insulin Resistance States: Basic and Clinical AspectsByAlessandra Gambineri;Alessandra GambineriEndocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, ItalySearch for other works by this author on:Laura Zanotti;Laura ZanottiEndocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, ItalySearch for other works by this author on:Daniela Ibarra-GaspariniDaniela Ibarra-GaspariniEndocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, ItalySearch for other works by this author on: