Brains are not preserved in the fossil record but endocranial casts are. These are casts of the internal bony braincase, revealing approximate brain size and shape, and they are also informative about brain surface morphology. Endocasts are the only direct evidence of human brain evolution, but they provide only limited data (‘paleoneurology'). This review discusses some new fossil endocasts and recent methodological advances that have allowed novel analyses of old endocasts, leading to intriguing findings and hypotheses. The interpretation of paleoneurological data always relies on comparative information from living species whose brains and behavior can be directly investigated. It is therefore important that future studies attempt to better integrate different approaches. Only then will we be able to gain a better understanding about hominin brain evolution.

Keywords:
Hominin brain evolution, Endocast, Paleoneurology, Computed tomography scans, Geometric morphometrics, Evo devo
1.
Aiello LC, Wheeler P (1995): The expensive-tissue hypothesis: the brain and the digestive system in human and primate evolution. Curr Anthropol 36:199.
2.
Aldridge K (2011): Patterns of differences in brain morphology in humans as compared to extant apes. J Hum Evol 60:94-105.
3.
Allen JS, Bruss J, Damasio H (2006): Looking for the lunate sulcus: a magnetic resonance imaging study in modern humans. Anat Rec A Discov Mol Cell Evol Biol 288:867-876.
4.
Baab KL, McNulty KP (2009): Size, shape, and asymmetry in fossil hominins: the status of the LB1 cranium based on 3D morphometric analyses. J Hum Evol 57:608-622.
5.
Baab KL, McNulty KP, Harvati K (2013): Homo floresiensis contextualized: a geometric morphometric comparative analysis of fossil and pathological human samples. PLoS One 8:e69119.
6.
Barney A, Martelli S, Serrurier A, Steele J (2012): Articulatory capacity of Neanderthals, a very recent and human-like fossil hominin. Philos Trans R Soc Lond B Biol Sci 367:88-102.
7.
Bastir M (2008): A systems-model for the morphological analysis of integration and modularity in human craniofacial evolution. J Anthropol Sci 86:37-58.
8.
Bastir M, Rosas A (2006): Correlated variation between the lateral basicranium and the face: a geometric morphometric study in different human groups. Arch Oral Biol 51:814-824.
9.
Bastir M, Rosas A (2009): Mosaic evolution of the basicranium in Homo and its relation to modular development. Evol Biol 36:57-70.
10.
Bastir M, Rosas A, O'Higgins P (2006): Craniofacial levels and the morphological maturation of the human skull. J Anat 209:637-654.
11.
Bastir M, Rosas A, Stringer C, Manuel Cuétara J, Kruszynski R, Weber GW, Ross CF, Ravosa MJ (2010): Effects of brain and facial size on basicranial form in human and primate evolution. J Hum Evol 58:424-431.
12.
Berger LR, de Ruiter DJ, Churchill SE, Schmid P, Carlson KJ, Dirks PH, Kibii JM (2010): Australopithecus sediba: a new species of Homo-like australopith from South Africa. Science 328:195-204.
13.
Bianchi S, Stimpson CD, Bauernfeind AL, Schapiro SJ, Baze WB, McArthur MJ, Bronson E, Hopkins WD, Semendeferi K, Jacobs B, Hof PR, Sherwood CC (2013a): Dendritic morphology of pyramidal neurons in the chimpanzee neocortex: regional specializations and comparison to humans. Cereb Cortex 23:2429-2436.
14.
Bianchi S, Stimpson CD, Duka T, Larsen MD, Janssen WG, Collins Z, Bauernfeind AL, Schapiro SJ, Baze WB, McArthur MJ, Hopkins WD, Wildman DE, Lipovich L, Kuzawa CW, Jacobs B, Hof PR, Sherwood CC (2013b): Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex resembles humans. Proc Natl Acad Sci USA 110(suppl 2):10395-10401.
15.
Biegert J (1957): Der Formwandel des Primatenschädels, und seine Beziehungen zur ontogenetischen Entwicklung und den phylogenetischen Spezialisationen der Kopforgane. Gegenb Morph Jahrb 98:77-199.
16.
Bienvenu T, Falk D, Semendeferi K, Guy F, Zollikofer C, Ponce de Léon M, Tafforeau P, Mackaye HT, Likius A, Vignaud P, Brunet M (2013a): The endocast of Sahelanthropus tchadensis, the earliest known hominid (7 Ma, Chad). Am J Phys Anthropol 150:80-81.
17.
Bienvenu T, Falk D, Semendeferi K, Guy F, Zollikofer C, Ponce de Léon M, Tafforeau P, Mackaye HT, Likius A, Vignaud P, Brunet M (2013b): Virtual reconstruction of the endocast of Sahelanthropus tchadensis. Paleoanthropology A5-A6.
18.
Bienvenu T, Guy F, Coudyzer W, Gilissen E, Roualdès G, Vignaud P, Brunet M (2011): Assessing endocranial variations in great apes and humans using 3D data from virtual endocasts. Am J Phys Anthropol 145:231-246.
19.
Bookstein FL (1991): Morphometric tools for landmark data: geometry and biology. Cambridge, Cambridge University Press.
20.
Bookstein FL (1997): Landmark methods for forms without landmarks: morphometrics of group differences in outline shape. Med Image Anal 1:225-243.
21.
Bookstein FL, Gunz P, Mitteroecker P, Prossinger H, Schaefer K, Seidler H (2003): Cranial integration in Homo: singular warps analysis of the midsagittal plane in ontogeny and evolution. J Hum Evol 44:167-187.
22.
Brown P, Sutikna T, Morwood MJ, Soejono RP, Jatmiko, Saptomo EW, Due RA (2004): A new small-bodied hominin from the Late Pleistocene of Flores, Indonesia. Nature 431:1055-1061.
23.
Brown TT, Lugar HM, Coalson RS, Miezin FM, Petersen SE, Schlaggar BL (2005): Developmental changes in human cerebral functional organization for word generation. Cereb Cortex 15:275-290.
24.
Brumm A, Aziz F, van den Bergh GD, Morwood MJ, Moore MW, Kurniawan I, Hobbs DR, Fullagar R (2006): Early stone technology on Flores and its implications for Homo floresiensis. Nature 441:624-628.
25.
Bruner E (2004): Geometric morphometrics and paleoneurology: brain shape evolution in the genus Homo. J Hum Evol 47:279-303.
26.
Bruner E, Manzi G, Arsuaga JL (2003): Encephalization and allometric trajectories in the genus Homo: evidence from the Neandertal and modern lineages. Proc Natl Acad Sci USA 100:15335-15340.
27.
Bruner E, Martin-Loeches M, Burgaleta M, Colom R (2011): Midsagittal brain shape correlation with intelligence and cognitive performance. Intelligence 39:141-147.
28.
Bruner E, Martin-Loeches M, Colom R (2010): Human midsagittal brain shape variation: patterns, allometry and integration. J Anat 216:589-599.
29.
Brunet M, Guy F, Pilbeam D, et al. (2002): A new hominid from the Upper Miocene of Chad, Central Africa. Nature 418:145-151.
30.
Burbano HA, Hodges E, Green RE, Briggs AW, Krause J, Meyer M, Good JM, Maricic T, Johnson PL, Xuan Z, Rooks M, Bhattacharjee A, Brizuela L, Albert FW, de la Rasilla M, Fortea J, Rosas A, Lachmann M, Hannon GJ, Pääbo S (2010): Targeted investigation of the Neandertal genome by array-based sequence capture. Science 328:723-725.
31.
Carlson KJ, Stout D, Jashashvili T, de Ruiter DJ, Tafforeau P, Carlson K, Berger LR (2011): The endocast of MH1, Australopithecus sediba. Science 333:1402-1407.
32.
Carper RA, Moses P, Tigue ZD, Courchesne E (2002): Cerebral lobes in autism: early hyperplasia and abnormal age effects. Neuroimage 16:1038-1051.
33.
Casey BJ, Tottenham N, Liston C, Durston S (2005): Imaging the developing brain: what have we learned about cognitive development? Trends Cogn Sci 9:104-110.
34.
Chandrasekaran C, Lemus L, Trubanova A, Gondan M, Ghazanfar AA (2011): Monkeys and humans share a common computation for face/voice integration. PLoS Comput Biol 7:e1002165.
35.
Changeux JP, Danchin A (1976): Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks. Nature 264:23-24.
36.
Charvet CJ, Darlington RB, Finlay BL (2013): Variation in human brains may facilitate evolutionary change toward a limited range of phenotypes. Brain Behav Evol 81:74-85.
37.
Charvet CJ, Striedter GF, Finlay BL (2011): Evo-devo and brain scaling: candidate developmental mechanisms for variation and constancy in vertebrate brain evolution. Brain Behav Evol 78:248-257.
38.
Chase PG, Dibble HL (1987): Middle Paleolithic symbolism: a review of current evidence and interpretations. J Anthropol Archaeol 6:263-296.
39.
Chechik G, Meilijson I, Ruppin E (1999): Neuronal regulation: a mechanism for synaptic pruning during brain maturation. Neural Comput 11:2061-2080.
40.
Chklovskii DB, Schikorski T, Stevens CF (2002): Wiring optimization in cortical circuits. Neuron 34:341-347.
41.
Chklovskii DB, Stevens CF (2000): Wiring optimization in the brain. Adv Neural Inf Process Sys 12:103-107.
42.
Conroy GC, Vannier MW (1984): Noninvasive three-dimensional computer imaging of matrix-filled fossil skulls by high-resolution computed tomography. Science 226:456-458.
43.
Conroy GC, Vannier MW, Tobias PV (1990): Endocranial features of Australopithecus africanus revealed by 2- and 3-D computed tomography. Science 247:838-841.
44.
Coqueugniot H, Hublin JJ (2007): Endocranial volume and brain growth in immature Neandertals. Period Biol 109:379-385.
45.
Coqueugniot H, Hublin JJ (2012): Age-related changes of digital endocranial volume during human ontogeny: results from an osteological reference collection. Am J Phys Anthropol 147:312-318.
46.
Coqueugniot H, Hublin JJ, Veillon F, Houët F, Jacob T (2004): Early brain growth in Homo erectus and implications for cognitive ability. Nature 431:299-302.
47.
Count EW (1947): Brain and body weight in man: their antecedents in growth and evolution - a study in dynamic somatometry. Ann NY Acad Sci 46:993-1122.
48.
Courchesne E, Carper R, Akshoomoff N (2003): Evidence of brain overgrowth in the first year of life in autism. JAMA 290:337-344.
49.
Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, Chisum HJ, Moses P, Pierce K, Lord C, Lincoln AJ, Pizzo S, Schreibman L, Haas RH, Akshoomoff NA, Courchesne RY (2001): Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology 57:245-254.
50.
Courchesne E, Pierce K, Schumann CM, Redcay E, Buckwalter JA, Kennedy DP, Morgan J (2007): Mapping early brain development in autism. Neuron 56:399-413.
51.
Courchesne E, Redcay E, Morgan JT, Kennedy DP (2005): Autism at the beginning: microstructural and growth abnormalities underlying the cognitive and behavioral phenotype of autism. Dev Psychopathol 17:577-597.
52.
Dart RA (1925): Australopithecus africanus: the man-ape of South Africa. Nature 115:195-199.
53.
Dawson G, Munson J, Webb SJ, Nalty T, Abbott R, Toth K (2007): Rate of head growth decelerates and symptoms worsen in the second year of life in autism. Biol Psychiatry 61:458-464.
54.
de Sousa AA, Sherwood CC, Mohlberg H, Amunts K, Schleicher A, MacLeod CE, Hof PR, Frahm H, Zilles K (2010): Hominoid visual brain structure volumes and the position of the lunate sulcus. J Hum Evol 58:281-292.
55.
Dementieva YA, Vance DD, Donnelly SL, Elston LA, Wolpert CM, Ravan SA, DeLong GR, Abramson RK, Wright HH, Cuccaro ML (2005): Accelerated head growth in early development of individuals with autism. Pediatr Neurol 32:102-108.
56.
d'Errico F (2003): The invisible frontier: a multiple species model for the origin of behavioral modernity. Evol Anthropol 12:188-202.
57.
DeSilva J, Lesnik J (2006): Chimpanzee neonatal brain size: implications for brain growth in Homo erectus. J Hum Evol 51:207-212.
58.
DeSilva JM, Lesnik JJ (2008): Brain size at birth throughout human evolution: a new method for estimating neonatal brain size in hominins. J Hum Evol 55:1064-1074.
59.
Dienske H (1986): A comparative approach to the question of why human infants develop so slowly; in: Else JG, Lee PC (eds): Primate Ontogeny, Cognition and Social Behaviour. Cambridge, Cambridge University Press, pp 147-154.
60.
Durrleman S, Pennec X, Trouvé A, Ayache N, Braga J (2011): Comparison of the endocranial ontogenies between chimpanzees and bonobos via temporal regression and spatiotemporal registration. J Hum Evol 62:74-88.
61.
Durston S, Davidson MC, Tottenham N, Spicer J, Galvan A, Fossella JA, Casey BJ (2004): Longitudinal functional MRI of the development of cognitive control. Soc Neurosci Abstr 319:18.
62.
Durston S, Hulshoff Pol HE, Casey BJ, Giedd JN, Buitelaar JK, van Engeland H (2001): Anatomical MRI of the developing human brain: what have we learned? J Am Acad Child Adolesc Psychiatry 40:1012-1020.
63.
Duterloo HS, Enlow DH (1970): A comparative study of cranial growth in Homo and Macaca. Am J Anat 127:357-368.
64.
Enlow DH (1990): Facial Growth. Philadelphia, Saunders.
65.
Fairbanks LA (2000): The developmental timing of primate play: a neural selection model; in: Taylor Parker S, Langer J, McKinney ML (eds): Biology, brains, and behavior - the evolution of human development. Santa Fe, School for American Research Press, pp 131-158.
66.
Falk D (1980a): Hominid brain evolution: the approach from paleoneurology. Yearb Phys Anthropol 23:93-107.
67.
Falk D (1980b): A reanalysis of the South African australopithecine natural endocasts. Am J Phys Anthropol 53:525-539.
68.
Falk D (1985): Apples, oranges, and the lunate sulcus. Am J Phys Anthropol 67:313-315.
69.
Falk D (1987): Hominid paleoneurology. Annu Rev Anthropol 16:13-28.
70.
Falk D (1989): Ape-like endocast of ‘ape-man' Taung. Am J Phys Anthropol 80:335-339.
71.
Falk D (2004): Hominin brain evolution - new century, new directions. Coll Antropol 28(suppl 2):59-64.
72.
Falk D (2012): Hominin paleoneurology: where are we now?; in Hofman MA, Falk D (eds): Progress in Brain Research - Evolution of the Primate Brain. Amsterdam, Elsevier, pp 255-272.
73.
Falk D (2014): Interpreting sulci on hominin endocasts: old hypotheses and new findings. Front Hum Neurosci 8:134.
74.
Falk D, Hildebolt C, Smith K, Morwood MJ, Sutikna T, Brown P, Jatmiko, Saptomo EW, Brunsden B, Prior F (2005): The brain of LB1, Homo floresiensis. Science 308:242-245.
75.
Falk D, Hildebolt C, Smith K, Morwood MJ, Sutikna T, Jatmiko, Saptomo EW, Imhof H, Seidler H, Prior F (2007): Brain shape in human microcephalics and Homo floresiensis. Proc Natl Acad Sci USA 104:2513-2518.
76.
Falk D, Hildebolt C, Smith K, Morwood MJ, Sutikna T, Jatmiko, Saptomo EW, Prior F (2009): LB1's virtual endocast, microcephaly, and hominin brain evolution. J Hum Evol 57:597-607.
77.
Falk D, Redmond JC, Guyer J, Conroy C, Recheis W, Weber GW, Seidler H (2000): Early hominid brain evolution: a new look at old endocasts. J Hum Evol 38:695-717.
78.
Finlayson C, Pacheco FG, Rodríguez-Vidal J, et al (2006): Late survival of Neanderthals at the southernmost extreme of Europe. Nature 443:850-853.
79.
Fragaszy DM, Bard K (1997): Comparison of development and life history in Pan and Cebus. Int J Primatol 18:683-701.
80.
Fragaszy DM, Visalberghi E, Fedigan LM (2004): The Complete Capuchin: The Biology of the Genus Cebus. Cambridge, Cambridge University Press.
81.
Gabounia L, de Lumley M-A, Vekua A, Lordkipanidze D, de Lumley H (2002): Découverte d'un nouvel hominidé à Dmanissi (Transcaucasie, Géorgie). Comptes Rendus Palevol 1:243-253.
82.
Gabunia L, Vekua A, Lordkipanidze D, Swisher CC, Ferring R, Justus A, Nioradze M, Tvalchrelidze M, Antón SC, Bosinski G, Jöris O, Lumley MA, Majsuradze G, Mouskhelishvili A (2000): Earliest Pleistocene hominid cranial remains from Dmanisi, Republic of Georgia: taxonomy, geological setting, and age. Science 288:1019-1025.
83.
Gale CR, O'Callaghan FJ, Godfrey KM, Law CM, Martyn CN (2004): Critical periods of brain growth and cognitive function in children. Brain 127:321-329.
84.
Ghazanfar AA (2013): Multisensory vocal communication in primates and the evolution of rhythmic speech. Behav Ecol Sociobiol 67:1441-1448.
85.
Giedd JN (2004): Structural magnetic resonance imaging of the adolescent brain. Ann NY Acad Sci 1021:77-85.
86.
Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, Paus T, Evans AC, Rapoport JL (1999): Brain development during childhood and adolescence: a longitudinal MRI study. Nat Neurosci 2:861-863.
87.
Gogtay N, Giedd JN, Lusk L, Hayashi KM, Greenstein D, Vaituzis AC, Nugent TF, Herman DH, Clasen LS, Toga AW, Rapoport JL, Thompson PM (2004): Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci USA 101:8174-8179.
88.
Golovanova LV, Hoffecker JF, Kharitonov VM, Romanova GP (1999): Mezmaiskaya cave: a Neanderthal occupation in the northern Caucasus. Curr Anthropol 40:77-86.
89.
Gomez-Robles A, Hopkins D, Sherwood C (2013): Increased morphological asymmetry, evolvability and plasticity in human brain evolution. Proc R Soc B Biol Sci 280:20130575.
90.
Gould SJ (1977): Ontogeny and Phylogeny. Cambridge, Belknap Press.
91.
Gower JC (1975): Generalized procrustes analysis. Pyschometrika 40:33-51.
92.
Green RE, Krause J, Briggs AW, et al (2010): A draft sequence of the Neandertal genome. Science 328:710-722.
93.
Green RE, Krause J, Ptak SE, Briggs AW, Ronan MT, Simons JF, Du L, Egholm M, Rothberg JM, Paunovic M, Pääbo S (2006): Analysis of one million base pairs of Neanderthal DNA. Nature 444:330-336.
94.
Gunz P, Mitteroecker P, Bookstein FL (2005): Semilandmarks in three dimensions; in Slice DE (ed): Modern Morphometrics in Physical Anthropology. New York, Kluwer Academic/Plenum Publishers, pp 73-98.
95.
Gunz P, Mitteroecker P, Neubauer S, Weber GW, Bookstein FL (2009): Principles for the virtual reconstruction of hominin crania. J Hum Evol 57:48-62.
96.
Gunz P, Neubauer S, Golovanova L, Doronichev V, Maureille B, Hublin JJ (2012): A uniquely modern human pattern of endocranial development: insights from a new cranial reconstruction of the Neandertal newborn from Mezmaiskaya. J Hum Evol 62:300-313.
97.
Gunz P, Neubauer S, Maureille B, Hublin JJ (2010): Brain development after birth differs between Neanderthals and modern humans. Curr Biol 20:R921-R922.
98.
Gunz P, Neubauer S, Maureille B, Hublin JJ (2011): Virtual reconstruction of the Le Moustier 2 newborn skull: implications for Neandertal ontogeny. Paleo 22:155-172.
99.
Hamann K, Warneken F, Greenberg JR, Tomasello M (2011): Collaboration encourages equal sharing in children but not in chimpanzees. Nature 476:328-331.
100.
Harvey PH, Martin RD, Clutton-Brock TH (1987): Life histories in comparative perspective; in Smuts BB, Cheney DL, Seyfarth RM, Wrangham RW, Struhsaker TT (eds): Primate societies. Chicago, University of Chicago Press, pp 181-196.
101.
Hazlett HC, Poe M, Gerig G, Smith RG, Provenzale J, Ross A, Gilmore J, Piven J (2005): Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years. Arch Gen Psychiat 62:1366-1376.
102.
Herculano-Houzel S (2009): The human brain in numbers: a linearly scaled-up primate brain. Front Hum Neurosci 3:31.
103.
Herculano-Houzel S (2011): Brains matter, bodies maybe not: the case for examining neuron numbers irrespective of body size. Ann NY Acad Sci 1225:191-199.
104.
Herculano-Houzel S (2012): The remarkable, yet not extraordinary, human brain as a scaled-up primate brain and its associated cost. Proc Natl Acad Sci USA 109(suppl 1):10661-10668.
105.
Herculano-Houzel S, Collins CE, Wong P, Kaas JH (2007): Cellular scaling rules for primate brains. Proc Natl Acad Sci USA 104:3562-3567.
106.
Hershkovitz I, Kornreich L, Laron Z (2007): Comparative skeletal features between Homo floresiensis and patients with primary growth hormone insensitivity (Laron syndrome). Am J Phys Anthropol 134:198-208.
107.
Herschkowitz N (2000): Neurological bases of behavioral development in infancy. Brain Dev 22:411-416.
108.
Hockfield S, Lombroso PJ (1998): Development of the cerebral cortex: IX. Cortical development and experience: I. J Am Acad Child Adolesc Psychiatry 37:992-993.
109.
Hofman MA (1989): On the evolution and geometry of the brain in mammals. Prog Neurobiol 32:137-158.
110.
Hofman MA (2012): Design principles of the human brain: an evolutionary perspective; in Hoffman MA, Falk D (eds): Evolution of the Primate Brain: From Neuron to Behavior. London, Elsevier, pp 373-390.
111.
Holloway RL (1978): The relevance of endocasts for studying primate brain evolution; in Noback CR (ed): Sensory Systems of Primates. New York, Plenum Press, pp 181-200.
112.
Holloway RL (1984): The Taung endocast and the lunate sulcus: a rejection of the hypothesis of its anterior position. Am J Phys Anthropol 64:285-287.
113.
Holloway RL (1985): The past, present, and future significance of the lunate sulcus in early hominid evolution; in Tobias PV (ed): Hominid Evolution: Past, Present, and Future. New York, Liss, pp 47-62.
114.
Holloway RL, Broadfield DC, Yuan MS (2004a): The Human Fossil Record: Brain Endocasts, the Paleoneurological Evidence. Hoboken, Wiley-Liss.
115.
Holloway RL, Clarke RJ, Tobias PV (2004b): Posterior lunate sulcus in Australopithecus africanus: was Dart right? Comptes Rendus Palevol 3:287-293.
116.
Holt AB, Cheek DB, Mellits ED, Hill DE (1975): Brain size and the relation of the primate to the nonprimate; in Cheek DB (ed): Foetal and Postnatal Cellular Growth: Hormones and Nutrition. New York, Wiley, pp 23-44.
117.
Hublin JJ (2014): Paleoanthropology: Homo erectus and the Limits of a Paleontological Species. Curr Biol 24:R82-R84.
118.
Hublin JJ, Coqueugniot H (2006): Absolute or proportional brain size: that is the question. A reply to Leigh's (2006) comments. J Hum Evol 50:109-113.
119.
Huffman OF (2001): Geologic context and age of the Perning/Mojokerto Homo erectus, East Java. J Hum Evol 40:353-362.
120.
Huffman OF, Zaim Y, Kappelman J, Ruez DR, de Vos J, Rizal Y, Aziz F, Hertler C (2006): Relocation of the 1936 Mojokerto skull discovery site near Perning, East Java. J Hum Evol 50:431-451.
121.
Huttenlocher PR (2002): Neural Plasticity: The Effects of Environment on the Development of the Cerebral Cortex. Cambridge, Harvard University Press.
122.
Jacob T, Indriati E, Soejono RP, Hsü K, Frayer DW, Eckhardt RB, Kuperavage AJ, Thorne A, Henneberg M (2006): Pygmoid Australomelanesian Homo sapiens skeletal remains from Liang Bua, Flores: population affinities and pathological abnormalities. Proc Natl Acad Sci USA 103:13421-13426.
123.
Jeffery N (2003): Brain expansion and comparative prenatal ontogeny of the non-hominoid primate cranial base. J Hum Evol 45:263-284.
124.
Jeffery N (2005): Cranial base angulation and growth of the human fetal pharynx. Anat Rec A Discov Mol Cell Evol Biol 284:491-499.
125.
Jeffery N, Spoor F (2002): Brain size and the human cranial base: a prenatal perspective. Am J Phys Anthropol 118:324-340.
126.
Jolicoeur P, Baron G, Cabana T (1988): Cross-sectional growth and decline of human stature and brain weight in 19th-century Germany. Growth Dev Aging 52:201-206.
127.
Jordaan HV (1976): Newborn: adult brain ratios in hominid evolution. Am J Phys Anthropol 44:271-278.
128.
Kappeler PM, Pereira ME (2003): Primate Life Histories and Socioecology. Chicago, University of Chicago Press.
129.
Kennedy GE (2005): From the ape's dilemma to the weanling's dilemma: early weaning and its evolutionary context. J Hum Evol 48:123-145.
130.
Kivell TL, Kibii JM, Churchill SE, Schmid P, Berger LR (2011): Australopithecus sediba hand demonstrates mosaic evolution of locomotor and manipulative abilities. Science 333:1411-1417.
131.
Klein RG (2000): Archeology and the evolution of human behavior. Evol Anthropol Issues News Rev 9:17-36.
132.
Klein RG (2009): The Human Career: Human Biological and Cultural Origins. Chicago, The University of Chicago Press.
133.
Konopka G, Friedrich T, Davis-Turak J, Winden K, Oldham MC, Gao F, Chen L, Wang GZ, Luo R, Preuss TM, Geschwind DH (2012): Human-specific transcriptional networks in the brain. Neuron 75:601-617.
134.
Langer J (2000): The heterochronic evolution of primate cognitive development; in Taylor Parker S, Langer J, McKinney ML (eds): Biology, Brains, and Behavior - The Evolution of Human Development. Santa Fe, School for American Research Press, pp 215-235.
135.
Leigh SR (2004): Brain growth, life history, and cognition in primate and human evolution. Am J Primatol 62:139-164.
136.
Leigh SR (2006): Brain ontogeny and life history in Homo erectus. J Hum Evol 50:104-108.
137.
Leigh SR (2012): Brain size growth and life history in human evolution. Evol Biol 39:587-599.
138.
Leigh SR, Blomquist GE (2007): Life history; in Campbell CJ, Fuentes A, MacKinnon KC, Panger M, Bearder SK (eds): Primates in Perspective. Oxford, Oxford University Press, pp 396-407.
139.
Leonard WR, Robertson ML (1997): Comparative primate energetics and hominid evolution. Am J Phys Anthropol 102:265-281.
140.
Leonard WR, Robertson ML, Snodgrass JJ, Kuzawa CW (2003): Metabolic correlates of hominid brain evolution. Comp Biochem Physiol A Mol Integr Physiol 136:5-15.
141.
Lieberman DE, McBratney BM, Krovitz G (2002): The evolution and development of cranial form in Homo sapiens. Proc Natl Acad Sci USA 99:1134-1139.
142.
Lieberman DE, Ross CF, Ravosa MJ (2000): The primate cranial base: ontogeny, function, and integration. Am J Phys Anthropol Suppl 31:117-169.
143.
Lieberman P, Laitman JT, Reidenberg JS, Gannon PJ (1992): The anatomy, physiology, acoustics and perception of speech: essential elements in analysis of the evolution of human speech. J Hum Evol 23:447-467.
144.
Lordkipanidze D, Ponce de León MS, Margvelashvili A, Rak Y, Rightmire GP, Vekua A, Zollikofer CP (2013): A complete skull from Dmanisi, Georgia, and the evolutionary biology of early Homo. Science 342:326-331.
145.
Luders E, Narr KL, Thompson PM, Toga AW (2009): Neuroanatomical correlates of intelligence. Intelligence 37:156-163.
146.
Luncz LV, Mundry R, Boesch C (2012): Evidence for cultural differences between neighboring chimpanzee communities. Curr Biol 22:922-926.
147.
Malikovic A, Vucetic B, Milisavljevic M, Tosevski J, Sazdanovic P, Milojevic B, Malobabic S (2012): Occipital sulci of the human brain: variability and morphometry. Anat Sci Int 87:61-70.
148.
Martin RD (1983): Human Brain Evolution in an Ecological Context: 52nd James Arthur Lecture on the Evolution of the Human Brain. New York, American Museum of Natural History.
149.
Martin RD (1996): Scaling of the mammalian brain: the maternal energy hypothesis. Physiology 11:149.
150.
Martin RD, Maclarnon AM, Phillips JL, Dobyns WB (2006): Flores hominid: new species or microcephalic dwarf? Anat Rec A Discov Mol Cell Evol Biol 288:1123-1145.
151.
Maureille B (2002): A lost Neanderthal neonate found. Nature 419:33-34.
152.
McBrearty S, Brooks AS (2000): The revolution that wasn't: a new interpretation of the origin of modern human behavior. J Hum Evol 39:453-563.
153.
McFarlin SC, Barks SK, Tocheri MW, Massey JS, Eriksen AB, Fawcett KA, Stoinski TS, Hof PR, Bromage TG, Mudakikwa A, Cranfield MR, Sherwood CC (2013): Early brain growth cessation in wild Virunga mountain gorillas (Gorilla beringei beringei). Am J Primatol 75:450-463.
154.
McPherron SP, Alemseged Z, Marean CW, Wynn JG, Reed D, Geraads D, Bobe R, Béarat HA (2010): Evidence for stone-tool-assisted consumption of animal tissues before 3.39 million years ago at Dikika, Ethiopia. Nature 466:857-860.
155.
McKee JK (1993): Faunal dating of the Taung hominid fossil deposit. J Hum Evol 25:363-376.
156.
Meyer M, Fu Q, Aximu-Petri A, Glocke I, Nickel B, Arsuaga JL, Martínez I, Gracia A, de Castro JM, Carbonell E, Pääbo S (2014): A mitochondrial genome sequence of a hominin from Sima de los Huesos. Nature 505:403-406.
157.
Meyer M, Kircher M, Gansauge MT, et al (2012): A high-coverage genome sequence from an archaic Denisovan individual. Science 338:222-226.
158.
Mitteroecker P, Gunz P (2009): Advances in geometric morphometrics. Evol Biol 36:235-247.
159.
Mitteroecker P, Gunz P, Bookstein FL (2005): Heterochrony and geometric morphometrics: a comparison of cranial growth in Pan paniscus versus Pan troglodytes. Evol Dev 7:244-258.
160.
Moore MW, Brumm A (2009): Homo floresiensis and the African Oldowan; in Hovers E, Braun D: Interdisciplinary Approaches to the Oldowan. Dordrecht, Springer, pp 61-69.
161.
Moore MW, Sutikna T, Jatmiko, Morwood MJ, Brumm A (2009): Continuities in stone flaking technology at Liang Bua, Flores, Indonesia. J Hum Evol 57:503-526.
162.
Morwood MJ, O'Sullivan P, Susanto EE, Aziz F (2003): Revised age for Mojokerto 1, an early Homo erectus cranium from East Java, Indonesia. Aust Archaeol 57:1-4.
163.
Morwood MJ, Soejono RP, Roberts RG, Sutikna T, Turney CS, Westaway KE, Rink WJ, Zhao JX, van den Bergh GD, Due RA, Hobbs DR, Moore MW, Bird MI, Fifield LK (2004): Archaeology and age of a new hominin from Flores in eastern Indonesia. Nature 431:1087-1091.
164.
Moss ML (1962): The functional matrix; in Kraus BS, Riedel RA (eds): Vistas in Orthodontics. Philadelphia, Lea & Febiger, pp 85-98.
165.
Moss ML, Young RW (1960): A functional approach to craniology. Am J Phys Anthropol 18:281-292.
166.
Mraz KD, Green J, Dumont-Mathieu T, Makin S, Fein D (2007): Correlates of head circumference growth in infants later diagnosed with autism spectrum disorders. J Child Neurol 22:700-713.
167.
Mrzljak L, Uylings HB, Van Eden CG, Judás M (1990): Neuronal development in human prefrontal cortex in prenatal and postnatal stages. Prog Brain Res 85:185-222.
168.
Neubauer S, Gunz P, Hublin JJ (2009): The pattern of endocranial ontogenetic shape changes in humans. J Anat 215:240-255.
169.
Neubauer S, Gunz P, Hublin JJ (2010): Endocranial shape changes during growth in chimpanzees and humans: a morphometric analysis of unique and shared aspects. J Hum Evol 59:555-566.
170.
Neubauer S, Gunz P, Mitteroecker P, Weber GW (2004): Three-dimensional digital imaging of the partial Australopithecus africanus endocranium MLD 37/38. Can Assoc Radiol J 55:271-278.
171.
Neubauer S, Gunz P, Schwarz U, Hublin JJ, Boesch C (2012a): Brief communication: endocranial volumes in an ontogenetic sample of chimpanzees from the Taï Forest National Park, Ivory Coast. Am J Phys Anthropol 147:319-325.
172.
Neubauer S, Gunz P, Weber GW, Hublin JJ (2012b): Endocranial volume of Australopithecus africanus: new CT-based estimates and the effects of missing data and small sample size. J Hum Evol 62:498-510.
173.
Neubauer S, Hublin JJ (2012): The evolution of human brain development. Evol Biol 39:568-586.
174.
O'Connell CA, DeSilva JM (2013): Mojokerto revisited: evidence for an intermediate pattern of brain growth in Homo erectus. J Hum Evol 65:156-161.
175.
Passingham RE (1982): The Human Primate. San Francisco, WH Freeman.
176.
Passingham RE, Stephan KE, Kötter R (2002): The anatomical basis of functional localization in the cortex. Nat Rev Neurosci 3:606-616.
177.
Paus T (2005): Mapping brain maturation and cognitive development during adolescence. Trends Cogn Sci 9:60-68.
178.
Ponce de León MS, Golovanova L, Doronichev V, Romanova G, Akazawa T, Kondo O, Ishida H, Zollikofer CP (2008): Neanderthal brain size at birth provides insights into the evolution of human life history. Proc Natl Acad Sci USA 105:13764-13768.
179.
Ponce de León MS, Ledevin R, Zollikofer CP (2013): Exo- and endocranial ontogeny in hominoid primates. Am J Phys Anthropol 150:223.
180.
Portmann A (1941): Die Tragzeiten der Primaten und die Dauer der Schwangerschaft beim Menschen: ein Problem der vergleichenden Biologie. Rev Suisse Zool Geneve 48:511-548.
181.
Prüfer K, Racimo F, Patterson N, et al (2014): The complete genome sequence of a Neanderthal from the Altai Mountains. Nature 505:43-49.
182.
Purves D (1994): Neural Activity and the Growth of the Brain. Cambridge, Cambridge University Press.
183.
Rakic P (1972): Mode of cell migration to the superficial layers of fetal monkey neocortex. J Comp Neurol 145:61-83.
184.
Rakic P (1974): Neurons in rhesus monkey visual cortex: systematic relation between time of origin and eventual disposition. Science 183:425-427.
185.
Reich D, Green RE, Kircher M, et al (2010): Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 468:1053-1060.
186.
Reich D, Patterson N, Kircher M, Delfin F, Nandineni MR, Pugach I, Ko AM, Ko YC, Jinam TA, Phipps ME, Saitou N, Wollstein A, Kayser M, Pääbo S, Stoneking M (2011): Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania. Am J Hum Genet 89:516-528.
187.
Rengachary SS, Ellenbogen RG (2005): Principles of Neurosurgery. Edinburgh, Elsevier Mosby.
188.
Rice SH (2002): The role of heterochrony in primate brain evolution; in Minugh-Purvis N, McNamara KJ (eds): Human Evolution Through Developmental Change. Baltimore, The John Hopkins University Press, pp 154-170.
189.
Richtsmeier JT, Aldridge K, DeLeon VB, Panchal J, Kane AA, Marsh JL, Yan P, Cole TM (2006): Phenotypic integration of neurocranium and brain. J Exp Zool B Mol Dev Evol 306:360-378.
190.
Rilling JK, Insel TR (1999): The primate neocortex in comparative perspective using magnetic resonance imaging. J Hum Evol 37:191-223.
191.
Rohlf FJ (1993): Relative warp analysis and an example of its application to mosquito wings; in Marcus LF, Bello E, García-Valdecasas A (eds): Contributions to Morphometrics. Madrid, Monografias del Museo Nacional de Ciencias Naturales, pp 131-159.
192.
Rohlf FJ, Slice D (1990): Extensions of the Procrustes method for the optimal superimposition of landmarks. Syst Zool 39:40-59.
193.
Rosenberg KR, Trevathan WR (1996): Bipedalism and human birth: the obstetrical dilemma revisited. Evol Anthropol Issues News Rev 4:161-168.
194.
Rosenberg KR, Trevathan WR (2001): The evolution of human birth. Sci Am 285:72-77.
195.
Rosenberg K, Trevathan W (2002): Birth, obstetrics and human evolution. BJOG 109:1199-1206.
196.
Ross CF, Ravosa MJ (1993): Basicranial flexion, relative brain size, and facial kyphosis in nonhuman primates. Am J Phys Anthropol 91:305-324.
197.
Ruff CB, Trinkaus E, Holliday TW (1997): Body mass and encephalization in Pleistocene Homo. Nature 387:173-176.
198.
Schmelz M, Call J, Tomasello M (2011): Chimpanzees know that others make inferences. Proc Natl Acad Sci USA 108:3077-3079.
199.
Schmithorst VJ, Wilke M, Dardzinski BJ, Holland SK (2005): Cognitive functions correlate with white matter architecture in a normal pediatric population: a diffusion tensor MRI study. Hum Brain Mapp 26:139-147.
200.
Schoenemann PT, Budinger TF, Sarich VM, Wang WSY (2000): Brain size does not predict general cognitive ability within families. Proc Natl Acad Sci USA 97:4932.
201.
Schultz AH (1940): Growth and development of the chimpanzee. Contrib Embryol 28:1-63.
202.
Schultz AH (1941): The relative size of the cranial capacity in primates. Am J Phys Anthropol 28:273-287.
203.
Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akshoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E (2010): Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci 30:4419-4427.
204.
Scott N, Neubauer S, Hublin J-J, Gunz P (2014): A shared pattern of postnatal endocranial development in extant hominoids. Evol Biol DOI: 10.1007/s11692-014-9290-7.
205.
Semendeferi K, Lu A, Schenker N, Damasio H (2002): Humans and great apes share a large frontal cortex. Nat Neurosci 5:272-276.
206.
Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, Evans A, Rapoport J, Giedd J (2006): Intellectual ability and cortical development in children and adolescents. Nature 440:676-679.
207.
Sherwood CC, Gordon AD, Allen JS, Phillips KA, Erwin JM, Hof PR, Hopkins WD (2011): Aging of the cerebral cortex differs between humans and chimpanzees. Proc Natl Acad Sci USA 108:13029-13034.
208.
Sherwood CC, Stimpson CD, Raghanti MA, Wildman DE, Uddin M, Grossman LI, Goodman M, Redmond JC, Bonar CJ, Erwin JM, Hof PR (2006): Evolution of increased glia-neuron ratios in the human frontal cortex. Proc Natl Acad Sci USA 103:13606-13611.
209.
Slice DE (2007): Geometric morphometrics. Annu Rev Anthropol 36:261-281.
210.
Smith BH, Tompkins RL (1995): Toward a life history of the Hominidae. Annu Rev Anthropol 24:257-279.
211.
Somel M, Franz H, Yan Z, Lorenc A, Guo S, Giger T, Kelso J, Nickel B, Dannemann M, Bahn S, Webster MJ, Weickert CS, Lachmann M, Pääbo S, Khaitovich P (2009): Transcriptional neoteny in the human brain. Proc Natl Acad Sci USA 106:5743-5748.
212.
Somel M, Liu X, Khaitovich P (2013): Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci 14:112-127.
213.
Sowell ER, Peterson BS, Thompson PM, Welcome SE, Henkenius AL, Toga AW (2003): Mapping cortical change across the human life span. Nat Neurosci 6:309-315.
214.
Sowell ER, Thompson PM, Leonard CM, Welcome SE, Kan E, Toga AW (2004a): Longitudinal mapping of cortical thickness and brain growth in normal children. J Neurosci 24:8223-8231.
215.
Sowell ER, Thompson PM, Toga AW (2004b): Mapping changes in the human cortex throughout the span of life. Neuroscientist 10:372-392.
216.
Sparks BF, Friedman SD, Shaw DW, Aylward EH, Echelard D, Artru AA, Maravilla KR, Giedd JN, Munson J, Dawson G, Dager SR (2002): Brain structural abnormalities in young children with autism spectrum disorder. Neurology 59:184-192.
217.
Sperber GH (1989): Craniofacial Embryology. London, John Wright.
218.
Spoor F (2013): Palaeoanthropology: small-brained and big-mouthed. Nature 502:452-453.
219.
Spoor F, Leakey MG, Gathogo PN, Brown FH, Antón SC, McDougall I, Kiarie C, Manthi FK, Leakey LN (2007): Implications of new early Homo fossils from Ileret, east of Lake Turkana, Kenya. Nature 448:688-691.
220.
Swisher CC, Curtis GH, Jacob T, Getty AG, Suprijo A, Widiasmoro (1994): Age of the earliest known hominids in Java, Indonesia. Science 263:1118-1121.
221.
Teffer K, Buxhoeveden DP, Stimpson CD, Fobbs AJ, Schapiro SJ, Baze WB, McArthur MJ, Hopkins WD, Hof PR, Sherwood CC, Semendeferi K (2013): Developmental changes in the spatial organization of neurons in the neocortex of humans and common chimpanzees. J Comp Neurol 521:4249-4259.
222.
Tocheri MW, Orr CM, Jacofsky MC, Marzke MW (2008): The evolutionary history of the hominin hand since the last common ancestor of Pan and Homo. J Anat 212:544-562.
223.
Tocheri MW, Orr CM, Larson SG, Sutikna T, Jatmiko, Saptomo EW, Due RA, Djubiantono T, Morwood MJ, Jungers WL (2007): The primitive wrist of Homo floresiensis and its implications for hominin evolution. Science 317:1743-1745.
224.
Toga AW, Thompson PM, Sowell ER (2006): Mapping brain maturation. Trends Neurosci 29:148-159.
225.
Trevathan W (1987): Human Birth: An Evolutionary Perspective. New York, Aldine de Gruyter.
226.
Trevathan WR (1996): The evolution of bipedalism and assisted birth. Med Anthropol Q 10:287-290.
227.
Tsegai ZJ, Kivell TL, Gross T, Nguyen NH, Pahr DH, Smaers JB, Skinner MM (2013): Trabecular bone structure correlates with hand posture and use in hominoids. PLoS One 8: e78781.
228.
van Leeuwen M, Peper JS, van den Berg SM, Brouwer RM, Hulshoff Pol HE, Kahn RS, Boomsma DI (2009): A genetic analysis of brain volumes and IQ in children. Intelligence 37:181-191.
229.
Vannucci RC, Barron TF, Holloway RL (2011): Craniometric ratios of microcephaly and LB1, Homo floresiensis, using MRI and endocasts. Proc Natl Acad Sci USA 108:14043-14048.
230.
Vannucci RC, Barron TF, Holloway RL (2013): Frontal brain expansion during development using MRI and endocasts: relation to microcephaly and Homo floresiensis. Anat Rec 296:630-637.
231.
Vekua A, Lordkipanidze D, Rightmire GP, Agusti J, Ferring R, Maisuradze G, Mouskhelishvili A, Nioradze M, De Leon MP, Tappen M, Tvalchrelidze M, Zollikofer C (2002): A new skull of early Homo from Dmanisi, Georgia. Science 297:85-89.
232.
Vinicius L (2005): Human encephalization and developmental timing. J Hum Evol 49:762-776.
233.
Vrba ES (1998): Multiphasic growth models and the evolution of prolonged growth exemplified by human brain evolution. J Theor Biol 190:227-239.
234.
Wang GZ, Konopka G (2013): Decoding human gene expression signatures in the brain. Transcription 4:1-7.
235.
Wanifuchi H, Shimizu T, Maruyama T (2002): Age-related changes in the proportion of intracranial cerebrospinal fluid space measured using volumetric computerized tomography scanning. J Neurosurg 97:607-610.
236.
Weaver TD, Hublin JJ (2009): Neandertal birth canal shape and the evolution of human childbirth. Proc Natl Acad Sci USA 106:8151-8156.
237.
Webb SJ, Nalty T, Munson J, Brock C, Abbott R, Dawson G (2007): Rate of head circumference growth as a function of autism diagnosis and history of autistic regression. J Child Neurol 22:1182-1190.
238.
Weber GW, Bookstein FL (2011): Virtual anthropology: a guide to a new interdisciplinary field. London, Springer.
239.
Whiten A, Goodall J, McGrew WC, Nishida T, Reynolds V, Sugiyama Y, Tutin CE, Wrangham RW, Boesch C (1999): Cultures in chimpanzees. Nature 399:682-685.
240.
Wobber V, Herrmann E, Hare B, Wrangham R, Tomasello M (2014): Differences in the early cognitive development of children and great apes. Dev Psychobiol 56:547-573.
241.
Wolpoff MH, Hawks J, Senut B, Pickford M, Ahern J (2006): An ape or the ape: is the Toumaï TM 266 cranium a hominid? Paleoanthropology 2006:36-50.
242.
Zollikofer CPE (2002): A computational approach to paleoanthropology. Evol Anthropol 11:64-67.
243.
Zollikofer CPE, Ponce de León MS (2005): Virtual reconstruction: a primer in computer-assisted paleontology and biomedicine. Hoboken, Wiley Interscience.
244.
Zollikofer CP, Ponce de León MS (2010): The evolution of hominin ontogenies. Semin Cell Dev Biol 21:441-452.
245.
Zollikofer CP, Ponce de León MS, Lieberman DE, Guy F, Pilbeam D, Likius A, Mackaye HT, Vignaud P, Brunet M (2005): Virtual cranial reconstruction of Sahelanthropus tchadensis. Nature 434:755-759.
246.
Zollikofer CPE, Ponce De León MS, Martin RD (1998): Computer-assisted paleoanthropology. Evol Anthropol 6:41-54.
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