Very little is known about the brain organization of the suction filter feeder, Rhincodon typus, and how it compares to other orectolobiforms in light of its specialization as a plankton-feeder. Brain size and overall brain organization was assessed in two specimens of R. typus in relation to both phylogeny and ecology, using magnetic resonance imaging (MRI). In comparison to over 60 other chondrichthyan species, R. typus demonstrated a relatively small brain for its body size (expressed in terms of encephalization quotients and residuals), similar to the lamniforms Carcharodon carcharias, Cetorhinus maximus, and Carcharias taurus. R. typus possessed a relatively small telencephalon with some development of the dorsal pallium, which was suggestive of moderate social behavior, in addition to a relatively large diencephalon and a relatively reduced mesencephalon. The most notable characteristic of the brain of Rhincodon was a large and highly foliated cerebellum, one of the largest cerebellums within the chondrichthyan clade. Early development of the brain was qualitatively assessed using an in situ MRI scan of the brain and chondrocranium of a neonate specimen of R. typus. There was evidence that folding of the cerebellar corpus appeared in early development, although the depth and number of folds might vary ontogenetically in this species. Hierarchical cluster analysis and multidimensional scaling ordinations showed evidence of convergent evolution with the basking shark, Cetorhinus maximus, another large-bodied filter feeding elasmobranch, supporting the claim that organization of the brain is more similar in species with analogous but independently evolved lifestyles than those that share taxonomic classification.

Barton RA, Purvis A, Harvey PH (1995) Evolutionary radiation of visual and olfactory brain systems in primates, bats, and insectivores. Phil Trans R Soc Lond B 348:381–392.
Bauchot R, Platel R, Ridet JM (1976) Brain-body weight relationships in Selachii. Copeia 2:305–310.
Bauchot R, Bauchot ML, Platel R, Ridet JM (1977) The brains of Hawaiian tropical fishes: Brain size and evolution. Copeia 1:42–46.
Bennet PM, Harvey PH (1985) Brain size, development and metabolism in birds and mammals. J Zool 207:491–509.
Bodznick D (1991) Elasmobranch vision: Multimodal integration in the brain. J Exp Zool Suppl 256:108–116.
Brandstätter R, Kotrschal K (1990) Brain growth patterns in four European cyprinid fish species (Cyprinidae, Teleostei): Roach (Rutilus rutilus), bream (Abramis brama), common carp (Cyprinus carpio), and sabre carp (Pelecus cultratus). Brain Behav Evol 35:195–211.
Bres M (1993) The behaviour of sharks. Rev Fish Biol Fish 3:133–159.
Budeau DA, Verts BJ (1986) Relative brain size and structural complexity of habitats of chipmunks. J Mammal 67:579–581.
Butler AB (2003) Sensory systems and brain evolution across the bilateria: Commonalities and constraints. In: Sensory Processing in Aquatic Environments (Collin SP, Marshall NJ, eds), pp 375–388. New York, NY: Springer-Verlag.
Cheung WWL, Pitcher TJ, Pauly D (2005) A fuzzy logic expert system to estimate intrinsic extinction vulnerabilities of marine fishes to fishing. Biol Conserv 124:97–111.
Clarke KR (1993) Non-parametric multivariate analysis of changes in community structure. Aust J Ecol 18:117–143.
Clarke KR, Warwick RM (2001) Change in Marine Communities: An approach to statistical analysis and interpretation, ed 2. Plymouth, UK: PRIMER-E.
Clutton-Brock TH, Harvey PH (1980) Primates, brains, and ecology. J Zool 190:309–323.
Cohen JL, Duff TA, Ebbesson SOE (1973) Electrophysiological identification of a visual area in the shark telencephalon. Science 182:492–494.
Colman JG (1997) A review of the biology and ecology of the whale shark. J Fish Biol 51:1219–1234.
Compagno LJV (1984a) FAO Species Catalogue. Sharks of the world. An annotated and illustrated catalogue of shark species known to date. II. Carcharhiniformes. Rome, Italy: FAO Fisheries Synopsis.
Compagno LJV (1984b) FAO Species Catalogue. Sharks of the world. An annotated and illustrated catalogue of shark species known to date. I. Hexanchiformes to Lamniformes. Rome, Italy: FAO Fisheries Synopsis.
Compagno LJV (1988) Sharks of the Order Carcharhiniformes. Princeton, NJ: Princeton University Press.
Compagno LJV, Niem VH (1998a) Carcharhinidae. Requiem sharks. In: FAO Identification Guide for Fishery Purposes The Living Marine Resources of the Western Central Pacific (Carpenter KE, Niem VH, eds), pp 1312–1360. Rome, Italy: FAO Fisheries Synopsis.
Compagno LJV, Niem VH (1998b) Squalidae. Dogfish sharks. In: FAO Identification Guide for Fishery Purposes The Living Marine Resources of the Western Central Pacific (Carpenter KE, Niem VH, eds), pp 1213–1232. Rome, Italy: FAO Fisheries Synopsis.
Compagno LJV (1999) Checklist of living elasmobranchs. In: Sharks, Skates, and Rays: The Biology of Elasmobranch Fishes (Hamlet WC, ed), pp 471–498. Baltimore, MD: Johns Hopkins University Press.
Compagno LJV (2001) FAO Species Catalogue. Sharks of the world. An annotated and illustrated catalogue of shark species known to date. Bullhead, mackerel, and carpet sharks (Heterodontiformes, Lamniformes and Orectolobiformes). Rome, Italy: FAO Fisheries Synopsis.
Cordo PJ, Bell CC, Harnad S (eds) (1997) Motor Learning and Synaptic Plasticity in the Cerebellum. Cambridge, UK: Cambridge University Press.
Corfield JR, Wild JM, Cowan BR, Parsons S, Kubke MF (2008a) MRI of postmortem specimens of endangered species for comparative brain anatomy. Nat Protocol 3:597–605.
Corfield JR, Wild JM, Hauber ME, Parsons S, Kubke MF (2008b) Evolution of brain size in the Palaeognath lineage, with an emphasis on New Zealand ratites. Brain Behav Evol 71:87–99.
Cox G, Francis M (1997) Sharks and Rays of New Zealand. Canterbury, UK: Canterbury University Press.
Demski LS, Northcutt RG (1996) The brain and cranial nerves of the white shark: An evolutionary perspective. In: Great White Sharks: The Biology of Carcharodon carcharias (Klimley AP, Ainley DG, eds), pp 121–130. San Diego, CA: Academic Press.
Didier DA (2002) Two new species of chimaeroid fishes from the southwestern Pacific Ocean (Holocephali, Chimaeridae). Ichthyol Res 49:299–306.
Didier DA (2004) Phylogeny and classification of extant Holocephali. In: Biology of Sharks and Their Relatives (Carrier JC, Musick JA, Heithaus MR, eds), pp 115–135. New York, NY: CRC Press.
Duffy CAJ (2002) Distribution, seasonality, lengths, and feeding behaviour of whale sharks (Rhincodon typus) observed in New Zealand waters NZ J Freshwater Res 36:565–570.
Eckert SA, Stewart BS (2001) Telemetry and satellite tracking of the whale shark, Rhincodon typus, in the Sea of Cortez, Mexico, and the North Pacific Ocean. Environ Biol Fish 60:299–308.
Edelman RR, Hesselink JR, Zlatkin MB (1996) Clinical Magnetic Resonance Imaging. Vol 1–2, ed 2. Philadelphia, PA: WB Saunders Company.
Eisenberg JF, Wilson DE (1978) Relative brain size and feeding strategies in the Chiroptera. Evolution 32:740–751.
Eschmeyer WN, Herald ES, Hammann HH (1983) A field guide to Pacific coast fishes of North America. Boston, MA: Houghton Mifflin Company.
Everitt B (1978) Graphical Techniques for Multivariate Data. London:Heinemann.
Felsenstein J (1985) Phylogenies and the comparative method. Am Nat 125:1–15.
Finlay BL, Darlington RB (1995) Linked regularities in the development and evolution of mammalian brains. Science 268:1578–1584.
Finlay BL, Hersman MN, Darlington RB (1998) Patterns of vertebrate neurogenesis and the paths of vertebrate evolution. Brain Behav Evol 52:232–242.
Forbes JG, Morris HD, Wang K (2006) Multimodal imaging of the sonic organ of Porichthys notatus, the singing midshipman fish. Magn Res Med 24:321–331.
Freedman JA, Noakes DLG (2002) Why are there no really big bony fishes? A point-of-view on maximum body size in teleosts and elasmobranchs. Rev Fish Biol Fish 12:403–416.
Garland T, Janis CM (1993) Does metatarsal/femur ratio predict maximal running speed in cursorial mammals? J Zool Lond 229:133–151.
Garland T Jr, Harvey PH, Ives AR (1992) Procedures for the analysis of comparative data using phylogenetically independent contrasts. Syst Biol 41:18–32.
Garland T Jr, Dickerman AW, Janis CM, Jones JA (1993) Phylogenetic analysis of covariance by computer simulation. Syst Biol 42:265–292.
Garland T Jr, Midford PE, Ives AR (1999) An introduction to phylogenetically based statistical methods, with a new method for confidence intervals on ancestral values. Am Zool 39:374–388.
Garland T Jr, Ives AR (2000) Using the past to predict the present: Confidence intervals for regression equations in phylogenetic comparative methods. Am Nat 155:346–364.
Garman S (1913) The Plagiostomia (Sharks, Skates, and Rays). Memoirs of the Museum of Comparative Zoology. Cambridge, MA: Harvard University. Vol XXXVI.
Goto T (2001) Comparative anatomy, phylogeny, and cladistic classification of the order Orectolobiformes (Chondrichthyes, Elasmobranchii). Mem Grad Sch Fish Sci Hokkaido Univ 48:1–100.
Graeber RC (1978) Behavioral studies correlated with central nervous system integration of vision in sharks. In: Sensory Biology of Sharks, Skates, and Rays (Hodgson ES, Mathewson RF, eds), pp 195–225. Washington DC: U.S. Government Printing Office.
Graeber RC, Schroeder DM, Jane JA, Ebbesson SOE (1978) Visual discrimination following partial telencephalic ablations in nurse sharks (Ginglymostoma cirratum). J Comp Neurol 180:325–344.
Graham RT, Roberts CM (2007) Assessing the size, growth rate and structure of a seasonal population of whale sharks (Rhincodon typus Smith 1828) using conventional tagging and photo identification Fish Res 84:71–80.
Gruber SH, Myrberg AAJ (1977) Approaches to the study of the behavior of sharks. Am Zool 17:471–486.
Gunnerus JE (1765) Brugden (Squalus maximus), Beskrvenen ved JE Gunnerus. Det Trondhiemske Selskabs Skerifter 3:33–49, Pl. 2.
Hakeem AY, Hof PR, Sherwood CC, Switzer RC, Rasmussen LEL, Allman JM (2005) Brain of the African elephant (Loxodonta africana): Neuroanatomy from magnetic resonance images. Anat Rec 287A:1117–1127.
Harvey PH, Pagel MD (1991) The Comparative Method in Evolutionary Biology. Oxford, UK: Oxford University Press.
Harvey PH, Krebs JR (1990) Comparing brains. Science 249:140–146.
Highstein SM, Thach WT (eds) (2002) The Cerebellum: Recent Developments in Cerebellar Research. New York, NY: Ann NY Acad Sci, Vol 978.
Hofmann MH (1999) Nervous system. In: Sharks, Skates, and Rays: The Biology of Elasmobranch Fishes (Hamlet WC, ed), pp 273–299. Baltimore, MD: Johns Hopkins University Press.
Hopson JA (1979) Paleoneurology. In: Biology of the Reptilla (Gans C, Northcutt RG, Ulinski P, eds), pp 39–146. New York, NY: Academic Press.
Huber R, van Staaden MJ, Kaufman LS, Liem KF (1997) Microhabitat use, trophic patterns, and the evolution of brain structure in African cichlids. Brain Behav Evol 50:167–182.
Hueter RE, Tyminski J, de la Parra R (2008) Deep diving and distant travels: Vertical and horizontal movements of whale sharks (Rhincodon typus) tagged off Quintana Roo, Mexico. In: Joint Meeting of Ichthyologists and Herpetologists and the American Elasmobranch Society 23–28 July, Montreal, Canada.
Hunt GR, Corballis MC, Gray RD (2001) Laterality in tool manufacture by crows. Nature 414:707.
Hutcheon JM, Kirsch JW, Garland T Jr (2002) A comparative analysis of brain size in relation to foraging ecology and phylogeny in the Chiroptera. Brain Behav Evol 60:165–180.
Ito H, Yoshimoto M, Somiya H (1999) External brain form and cranial nerves of the megamouth shark, Megachasma pelagios. Copeia 1999:210–213.
Ives AR, Midford PE, Garland T Jr (2007) Within-species variation and measurement error in phylogenetic comparative methods. Syst Biol 56:252–270.
Jerison HJ (1973) Evolution of the Brain and Intelligence. New York, NY: Academic Press.
Johnson RH, Nelson DR (1973) Agonistic display in the gray reef shark, Carcharhinus menisorrah, and its relationship to attacks on man. Copeia 1973:76–84.
Kaufman JA, Ahrens ET, Laidlaw DH, Zhang S, Allman JM (2005) Anatomical analysis of an aye-aye brain (Daubentonia madagascariensis, Primates: Prosimii) combining histology, structural magnetic resonance imaging, and diffusion-tensor imaging. Anat Rec A 287A:1026–1037.
Kenkel NC, Orloci L (1986) Applying metric and nonmetric multidimensional scaling to some ecological studies: Some new results. Ecology 67:919–928.
Klimley AP (1985) Schooling in Sphyrna lewini, a species with a low risk of predation: A non-egalitarian state. J Comp Ethol 70:297–319.
Kotrschal K, van Staaden MJ, Huber R (1998) Fish brains: Evolution and environmental relationships. Rev Fish Biol Fish 8:373–408.
Kruska DCT (1988) The brain of the basking shark (Cetorhinus maximus). Brain Behav Evol 32:353–363.
Kruskal JB (1964) Multidimensional scaling by optimizing goodness of fit to a nonmetric hypothesis. Psychometrika 29:1–27.
Kruskal JB, Wish M (1978) Multidimensional Scaling. Beverly Hills, CA: Sage Publications.
Kyne PM, Simpfendorfer CA (2007) A collation and summarization of available data on deepwater chondrichthtyans: Biodiversity, life history and fisheries. In: A report prepared by the IUCN Shark Specialist Group for the Marine Conservation Biology Institute, 137 pp.
Last PR, Stevens JD (1994) Sharks and Rays of Australia. Melbourne, Australia: CSIRO.
Lefebvre L, Sol D (2008) Brains, lifestyles, and cognition: Are there general trends? Brain Behav Evol 72:135–144.
Lefebvre L, Gaxiola A, Dawson S, Timmermans S, Rosza L, Kabai P (1997) Feeding innovations and forebrain size in Australasian birds. Behaviour 135:1077–1097.
Lefebvre L, Nicolakakis N, Boire D (2002) Tools and brains in birds. Behaviour 139:939–973.
Lisney TJ, Bennett MB, Collin SP (2007) Volumetric analysis of sensory brain areas indicates ontogenetic shifts in the relative importance of sensory systems in elasmobranchs. Raffles B Zool 14:7–15.
Lisney TJ, Yopak KE, Montgomery JC, Collin SP (2008) Variation in brain organization and cerebellar foliation in chondrichthyans: Batoids. Brain Behav Evol 72:262–282.
Marino L, Murphy TL, Deweerd AL, Morris JA, Fobbs AJ, Humblot N, Ridgway SH, Johnson JI (2001a) Anatomy and three-dimensional reconstructions of the brain of the white whale (Delphinapterus leucas) from magnetic resonance images (MRI). Anat Rec 262:429–439.
Marino L, Sudheimer KD, Murphy TL, Davis KK, Pabst DA, McLellan WA, Rilling JK, Johnson JI (2001b) Anatomy and three-dimensional reconstructions of the brain of a bottlenose dolphin (Tursiops truncatus) from magnetic resonance images. Anat Rec 264:397–414.
Marino L, Sudheimer K, Pabst DA, McLellan WA, Johnson JI (2003) Magnetic resonance images of the brain of a dwarf sperm whale (Kogia simus). J Anat 203:57–76.
Martin AP, Naylor GJP, Palumbi SR (1992) Rates of mitochondrial DNA evolution in sharks are slow compared with mammals. Nature 357:153–155.
Martin RA (2007) A review of behavioural ecology of whale sharks (Rhincodon typus). Fish Res 84:10–16.
Masai H (1969) The brain patterns of sharks in relation to habit. J Hinforsch 11:347–365.
Montgomery JC, Carton G, Bodznick D (2002) Error-driven motor learning in fish. Biol Bull 203:238–239.
Montie EW, Schneider G, Ketten DR, Marino L, Touhey KE, Hahn ME (2008) Volumetric neuroimaging of the Atlantic white-sided dolphin (Lagenorhynchus acutus) brain from in situ magnetic resonance images. Anat Rec 291:263–282.
Motta PJ (2004) Prey capture behavior and feeding mechanisms of elasmobranchs. In: Biology of Sharks and Their Relatives (Carrier JC, Musick JA, Heithaus MR, eds), pp 165–202. London, UK: CRC Press.
Musick JA, Harbin MM, Compagno LJV (2004) Historical zoogeography of the Selachii. In: Biology of Sharks and Their Relatives (Carrier JC, Musick JA, Heithaus MR, eds), pp 33–78. London, UK: CRC Press.
Myagkov NA (1991) The brain sizes of living Elasmobranchii as their organization level indicator. I. General Analysis. J Hirnforsch 32:553–561.
Myrberg AAJ, Gruber S (1974) The behavior of the bonnethead shark, Sphyrna tiburo. Copeia 1974:358–374.
Narenda KS (1991) Adaptive control using neural networks. In: Neural Networks for Control (Miller WT, Sutton RS, Werbos PJ, eds), pp 115–142. Cambridge, MA: MIT Press.
Naylor GJP (1992) The phylogenetic relationships among requiem and hammerhead sharks: Inferring phylogeny when thousands of equally most parsimonious trees result. Cladistics 8:295–318.
Nelson JD (2004) Distribution and foraging ecology by whale sharks (Rhincodon typus) within Bahia de los Angeles, Baja California Norte, Norte, Mexico. University of San Diego, 115 pp.
New JG (2001) Comparative neurobiology of the elasmobranch cerebellum: Theme and variations on a sensorimotor interface. Environ Biol Fish 60:93–108.
Nilsson GE, Routley MH, Renshaw GMC (2000) Low mass-specific brain Na+/K+-ATPase activity in elasmobranch compared to teleost fishes: Implications for the large brain size of elasmobranchs. Proc R Soc Lond B 267:1335–1339.
Norman B (2000) Rhincodon typus. In: IUCN 2007. 2007 IUCN Red List of Threatened Species <>. Downloaded on 14 August 2008.
Northcutt RG (1977) Elasmobranch central nervous system organization and its possible evolutionary significance. Am Zool 17:411–429.
Northcutt RG (1978) Brain organization in the cartilaginous fishes. In: Sensory Biology of Sharks, Skates, and Rays (Hodgson ES, Mathewson RF, eds), pp 117–194. Arlington, VA: Office of Naval Research.
Oelschlager HHA, Haas-Rioth M, Fung C, Ridgway SH, Knauth M (2008) Morphology and evolutionary biology of the dolphin (Delphinus sp.) brain: MR imaging and conventional histology. Brain Behav Evol 71:68–86.
Pagel MD (1992) A method for the analysis of comparative data. J Theor Biol 156:431–442.
Paul DH, Roberts BL (1979) The significance of cerebellar function for a reflex movement of the dogfish. J Comp Physiol 134:69–74.
Paulin MG (1993) The role of the cerebellum in motor control and perception. Brain Behav Evol 41:39–51.
Paulin MG (1997) Neural representations of moving systems. Int Rev Neurobiol 41:515–533.
Perry CN, Cartamil DC, Bernal D, Sepulveda CA, Theilmann RJ, Graham JB, Frank LR (2007) Quantification of red myotomal muscle volume and geometry in the shortfin mako shark (Isurus oxyrinchus) and the salmon shark (Lamna ditropis), using T1-weighted magnetic resonance imaging. J Morph 268:284–292.
Pirlot P, Jolicoeur P (1982) Correlations between major brain regions in Chiroptera. Brain Behav Evol 20:172–181.
Pollen AA, Dobberfuhl AP, Scace J, Igulu MM, Renn SCP, Shumway CA, Hofmann HA (2007) Environmental complexity and social organization sculpt the brain in Lake Tanganyikan cichlid fish. Brain Behav Evol 70:21–39.
Purvis A, Rambaut A (1995a) Comparative Analysis by Independent Contrasts (CAIC): A statistical package for the Apple Macintosh: User’s Guide.
Purvis A, Rambaut A (1995b) Comparative analysis by independent contrasts (CAIC): An Apple Macintosh application for analyzing comparative data. Comp Appl Biosci 11: 247–251.
Riddell WI, Corl KG (1977) Comparative investigation and relationship between cerebral indices and learning abilities. Brain Behav Evol 14:305–308.
Ritter EK, Godknecht AJ (2000) Agonistic displays in the blacktip shark (Carcharhinus limbatus). Copeia 2000:282–284.
Rogers BL, Lowe CG, Fernández-Juricic E, Frank LR (2008) Utilizing magnetic resonance imaging (MRI) to assess the effects of angling-induced barotrauma on rockfish (Sebastes). Can J Fish Aquat Sci 65:1245–1249.
Rowat D, Gore M (2007) Regional scale horizontal and local scale vertical movements of whale sharks, in the Indian Ocean off Seychelles. Fish Res 84:32–40.
Sato Y (1986) Brain patterns of the whale and basking sharks, Rhincodon typus and Cetorhinus maximus in relation to systematics. Zool Sci 3:1115.
Sepulveda CA, Dickson K, Frank LR, Graham JB (2007) Cranial endothermy and a putative brain heater in the most basal tuna species, Allothunnus fallai. J Fish Biol 70:1720–1733.
Shirai S (1992) Phylogenetic relationships of the angel sharks, with comments on elasmobranch phylogeny (Chondrichthyes, Squatinidae). Copeia 1992:505–518.
Shirai S (1996) Phylogenetic interrelationships of neoselachains (Chondrichthyes: Euselachii). In: Interrelationships of Fishes (Stiassny MLJ, Parenti LR, Johnson GD, eds), pp 9–34. San Diego, CA: Academic Press.
Shumway CA (2008) Habitat complexity, brain, and behavior. Brain Behav Evol 72:123–134.
Smeets WJAJ, Nieuwenhuys R, Roberts BL (1983) The Central Nervous System of Cartilaginous Fishes: Structural and Functional Correlations. New York, NY: Springer Verlag.
Smeets WJAJ (1998) Cartilaginous fishes. In: The Central Nervous System of Vertebrates (Nieuwenhuys R, Roberts BL, eds), pp 551–654. Berlin, Germany: Springer Verlag.
Smith A (1828) Descriptions of new, or imperfectly known objects of the animal kingdom, found in the south of Africa. S Afr Comm Advertiser 3:2.
Smith RJ (2002) Estimation of body mass in paleontology. J Human Evol 42:271–287.
Springer S (1967) Social organization of shark populations. In: Sharks, Skates and Rays (Gilbert PW, Mathewson RF, Rall DP, eds), pp 149–174. Baltimore, MD: Johns Hopkins University Press.
Stevens JD (2007) Whale shark (Rhincodon typus) biology and ecology: A review of the primary literature. Fish Res 84:4–9.
Stewart BS, Wilson SG (2005) Threatend fishes of the world: Rhincodon typus (Smith, 1828) (Rhincodontidae). Environ Biol Fish 74:184–185.
Striedter GF (2005) Principles of Brain Evolution. Sunderland, MA: Sinauer Associates, Inc.
Taylor G (1994) Whale Sharks: The Giants of Ningaloo Reef. Sydney, Australia: Angus and Robertson.
Taylor LR Jr, Compagno LJV, Struhsaker PJ (1983) Megamouth: A new species, genus, and family of lamnoid shark (Megachasma pelagios, family Megachasmidae) from the Hawaiian Islands. Proc Cal Acad Sci 43:87–110.
Tobias PV (2001) Re-creating ancient hominid virtual endocasts by CT-scanning. Clinical Anat 14:134–141.
Tricas TC, Deacon K, Last P, McCosker JE, Walker TI, Taylor L (1997) Sharks and Rays. Sydney, Australia: Reader’s Digest.
van Dongen PAM (1998) Brain size in vertebrates. In: The Central Nervous System of Vertebrates (Nieuwenhuys R, Smeets WJAJ, Meek J, Ten Donkelaar HJ, Nicholson C, eds), pp 2100–2134. Berlin: Springer Verlag.
Wagner HJ (2001a) Brain areas in abyssal demersal fishes. Brain Behav Evol 57:301–316.
Wagner HJ (2001b) Sensory brain areas in mesopelagic fishes. Brain Behav Evol 57:117–133.
Wilga CAD, Lauder GV (2004) Biomechanics of locomotion in sharks, rays, and chimaeras. In: Biology of Sharks and Their Relatives (Carrier JC, Musick JA, Heithaus MR, eds), pp 139–202. London, UK: CRC Press.
Wilson SG, Polovina JJ, Stewart BS, Meekan MG (2006) Movement of whale sharks (Rhincodon typus) tagged at Ningaloo Reef, Western Australia. Marine Biol 148:1157–1166.
Yopak KE, Frank LR (2007) Variation in cerebellar foliation in cartilaginous fishes: Ecological and behavioral considerations. Brain Behav Evol 70:210.
Yopak KE, Lisney TJ, Collin SP, Montgomery JC (2007) Variation in brain organization and cerebellar foliation in chondrichthyans: Sharks and holocephalans. Brain Behav Evol 69:280–300.
Yopak KE, Montgomery JC (2008) Brain organization and specialization in deep-sea chondrichthyans. Brain Behav Evol 71:287–304.
Yopak KE, Balls G, Frank LR (2009) Cortical Surface Structure Analysis in Sharks using Magnetic Resonance Imaging (MRI). Proc of ISMRM 17:2925.
Yushkevich PA, Piven J, Cody Hazlett H, Gimpel Smith R, Ho S, Gee JC, Gerig G (2006) User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability. Neuroimage 31:1116–11128.
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