Background: Previous studies found a relationship between audiometric patterns and the risk of developing vascular disease and considered the strial and low-sloping hearing loss of interest in predicting vascular disease. Objective: The aim of this study was to assess whether low-frequency audiometric patterns can be associated with the presence of vascular risk in a group of age-related hearing loss (ARHL) patients. Methods: A retrospective case series of 156 patients diagnosed with ARHL between July 2021 and July 2022 was assessed for a possible correlation between vascular risk factors (e.g., high blood pressure [HBP], diabetes mellitus [DM], and dyslipidemia [DLP]) and audiometric patterns. Results: One hundred fifty-six patients (79 women and 77 men) with a mean age of 73.2 ± 10.9 years who were diagnosed with ARHL were studied. A low-frequency audiometric notch at 250 Hz or 500 Hz verified in 36 patients was significantly associated with the presence of HBP, DM, or DLP (adjusted odds ratio [OR] 3.54, 95% confidence interval [CI]: 1.48–8.46, p < 0.001). A positive association between low-frequency hearing loss and the presence of at least 1 cardiovascular risk factor (adjusted OR 2.16, 95% CI: 1.01–4.62, p = 0.046) was verified. No other association was observed between audiometric patterns and vascular risk factors. Conclusion: Low-frequency audiometric notches might be related to vascular risk in ARHL patients and merit future attention in larger population studies.

1.
American Speech-Language-Hearing Association [Internet]
Guidelines for manual pure-tone threshold audiometry
.
2023
. (cited 2023 February 9). Available from: www.asha.org/policy.
2.
Arvin
B
,
Prepageran
N
,
Raman
R
.
“High frequency presbycusis”-is there an earlier onset
.
Indian J Otolaryngol Head Neck Surg
.
2013
65
Suppl 3
480
4
.
3.
Baiduc
RR
,
Poling
GL
,
Hong
O
,
Dhar
S
.
Clinical measures of auditory function: the cochlea and beyond
.
Dis Mon
.
2013
;
59
(
4
):
147
56
.
4.
Bertrand
RA
,
Huang
Z
.
Association between audiometric patterns and probabilities of cardiovascular diseases
.
Laryngoscope Investig Otolaryngol
.
2018
;
3
(
6
):
478
85
.
5.
Bowl
MR
,
Dawson
SJ
.
Age-related hearing loss
.
Cold Spring Harb Perspect Med
.
2019
9
8
a033217
.
6.
Cruickshanks
KJ
,
Nondahl
DM
,
Dalton
DS
,
Fischer
ME
,
Klein
BEK
,
Klein
R
.
Smoking, central adiposity, and poor glycemic control increase risk of hearing impairment
.
J Am Geriatr Soc
.
2015
;
63
(
5
):
918
24
.
7.
Davis
A
,
McMahon
CM
,
Pichora-Fuller
KM
,
Russ
S
,
Lin
F
,
Olusanya
BO
.
Aging and hearing health: the life-course approach
.
Gerontologist
.
2016
56
Suppl 2
256
67
.
8.
Engdahl
B
,
Aarhus
L
,
Lie
A
,
Tambs
K
.
Cardiovascular risk factors and hearing loss: the HUNT study
.
Int J Audiol
.
2015
;
54
(
12
):
958
66
.
9.
Fisch
U
,
Dobozi
M
,
Greig
D
.
Degenerative changes of the arterial vessels of the internal auditory meatus during the process of aging. A histological study
.
Acta Otolaryngol
.
1972
;
73
(
2
):
259
66
.
10.
Friedland
DR
,
Cederberg
C
,
Tarima
S
.
Audiometric pattern as a predictor of cardiovascular status: development of a model for assessment of risk
.
Laryngoscope
.
2009
;
119
(
3
):
473
86
.
11.
Gates
GA
,
Schmid
P
,
Kujawa
SG
,
Nam
B
,
D’Agostino
R
.
Longitudinal threshold changes in older men with audiometric notches
.
Hear Res
.
2000
141
1–2
220
8
.
12.
Horikawa
C
,
Kodama
S
,
Tanaka
S
,
Fujihara
K
,
Hirasawa
R
,
Yachi
Y
.
Diabetes and risk of hearing impairment in adults: a meta-analysis
.
J Clin Endocrinol Metab
.
2013
;
98
(
1
):
51
8
.
13.
Hull
RH
,
Kerschen
SR
.
The influence of cardiovascular health on peripheral and central auditory function in adults: a research review
.
Am J Audiol
.
2010
;
19
(
1
):
9
16
.
14.
Johnsson
LG
,
Hawkins
JE
Jr
.
Vascular changes in the human inner ear associated with aging
.
Ann Otol Rhinol Laryngol
.
1972a
81
3
364
76
.
15.
Johnsson
LG
,
Hawkins
JE
Jr
.
Symposium on basis ear research. II. Strial atrophy in clinical and experimental deafness
.
Laryngoscope
.
1972b
82
7
1105
25
.
16.
Kurata
N
,
Schachern
PA
,
Paparella
MM
,
Cureoglu
S
.
Histopathologic evaluation of vascular findings in the cochlea in patients with presbycusis
.
JAMA Otolaryngol Head Neck Surg
.
2016
;
142
(
2
):
173
8
.
17.
Lebech Cichosz
S
,
Hejlesen
O
.
Association between diabetes and changes in hearing: a cross-sectional study
.
Diabetes Metab
.
2018
;
44
(
1
):
87
90
.
18.
Lowell
SH
,
Paparella
MM
.
Presbycusis: what is it
.
Laryngoscope
.
1977
87
10 Pt 1
1710
7
.
19.
Marcucci
R
,
Alessandrello Liotta
A
,
Cellai
AP
,
Rogolino
A
,
Berloco
P
,
Leprini
E
.
Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss
.
J Thromb Haemost
.
2005
;
3
(
5
):
929
34
.
20.
Rolim
LP
,
Samelli
AG
,
Moreira
RR
,
Matas
CG
,
Santos
IS
,
Bensenor
IM
.
Effects of diabetes mellitus and systemic arterial hypertension on elderly patients’ hearing
.
Braz J Otorhinolaryngol
.
2018
;
84
(
6
):
754
63
.
21.
Schuknecht
HF
.
Further observations on the pathology of presbycusis
.
Arch Otolaryngo
.
1964
;
80
:
369
82
.
22.
Simões
J
,
Vlaminck
S
,
Seiça
R
,
Acke
F
,
Miguéis
A
.
Cardiovascular risk and sudden sensorineural hearing loss: a systematic review and meta-analysis
.
Laryngoscope
.
2023
;
133
(
1
):
15
24
.
23.
Susmano
A
,
Rosenbush
SW
.
Hearing loss and ischemic heart disease
.
Am J Otol
.
1988
;
9
(
5
):
403
8
.
24.
Tan
HE
,
Lan
NSR
,
Knuiman
MW
,
Divitini
ML
,
Swanepoel
DW
,
Hunter
M
.
Associations between cardiovascular disease and its risk factors with hearing loss-a cross-sectional analysis
.
Clin Otolaryngol
.
2018
;
43
(
1
):
172
81
.
25.
Watson
N
,
Ding
B
,
Zhu
X
,
Frisina
RD
.
Chronic inflammation: inflammaging–in the ageing cochlea: a novel target for future presbycusis therapy
.
Ageing Res Rev
.
2017
;
40
:
142
8
.
26.
Wattamwar
K
,
Qian
ZJ
,
Otter
J
,
Leskowitz
MJ
,
Caruana
FF
,
Siedlecki
B
.
Association of cardiovascular comorbidities with hearing loss in the older old
.
JAMA Otolaryngol Head Neck Surg
.
2018
;
144
(
7
):
623
9
.
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