Introduction: Ménière’s disease (MD) is a disease of the inner ear. In Asian countries, there is one previous epidemiologic study that used a retrospective survey of a specific district. Previous studies have demonstrated that weather variables are strongly associated with symptom aggravation in MD. However, no study has reported on seasonal variation of MD. Methods: We conducted a retrospective population-based study using the Korean national health insurance claims database (NHICD). In the present study, the prevalence and incidence of MD from 2013 to 2017 were calculated. Prevalence and incidence of MD according to sex, age group, and monthly incidence are presented. Seasonal incidence was calculated for four seasons. The seasonal average humidity and atmospheric pressure were also calculated. Results: The incidence rate of MD showed a rapid yearly increase from 2013 to 2017 in Korea. The prevalence and incidence rate by age group continued to increase up to the 70 year olds. The female-to-male ratio was 2.17. The seasonal incidence of MD was relatively high in summer and autumn and relatively low in winter and spring; however, there were no significant differences. Discussion/Conclusions: The rapid progression to an aging society, increase in medical accessibility, and lifestyle changes could be the reasons for the elevation of the incidence rate in the Korean population. Consistent with a previous study, the incidence of MD was higher in seasons with high humidity and low atmospheric pressure; however, there were no significant differences. Further studies about the relationship between diet and MD, seasonality of MD with long-term analysis, and investigating the underlying mechanisms connecting weather and MD are needed.

1.
Bruderer
SG
,
Bodmer
D
,
Stohler
NA
,
Jick
SS
,
Meier
CR
.
Population-based study on the epidemiology of Ménière’s disease
.
Audiol Neurotol
.
2017
;
22
(
2
):
74
82
.
[PubMed]
1420-3030
2.
Cho
MO
.
Health care seeking behavior of Korean women with lymphedema
.
Nurs Health Sci
.
2004
Jun
;
6
(
2
):
149
59
.
[PubMed]
1441-0745
3.
Committee on Hearing and Equilibrium
.
Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere’s disease
.
Otolaryngol Head Neck Surg
.
1995
Sep
;
113
(
3
):
181
5
.
[PubMed]
0194-5998
4.
Davis
G
,
Ralph
J.
Yamaha Sound Reinforcement Handbook. 2.
1987
.
5.
DePalma
SM
,
Himmelfarb
CD
,
MacLaughlin
EJ
,
Taler
SJ
.
Hypertension guideline update: A new guideline for a new era
.
JAAPA
.
2018
Jun
;
31
(
6
):
16
22
.
[PubMed]
1547-1896
6.
Derebery
MJ
,
Berliner
KI
.
Prevalence of allergy in Meniere’s disease
.
Otolaryngol Head Neck Surg
.
2000
Jul
;
123
(
1 Pt 1
):
69
75
.
[PubMed]
0194-5998
7.
Laura
G
,
Diego
C
,
Roberto
P
,
Ennio
N
,
Mara
F
,
Elisabetta
Z
, et al
Update on vertigo in autoimmune disorders, from diagnosis to treatment
.
J Immunol Res
. 2314-7156
8.
Guerra-Jiménez
G
,
Arenas Rodríguez
A
,
Falcón González
JC
,
Pérez Plasencia
D
,
Ramos Macías
Á
.
Epidemiology of vestibular disorders in the otoneurology unit
.
Acta Otorrinolaringol Esp
.
2017
Nov - Dec
;
68
(
6
):
317
22
.
[PubMed]
0001-6519
9.
Hallpike
CS
,
Cairns
H
.
Observations on the Pathology of Ménière’s Syndrome: (Section of Otology)
.
Proc R Soc Med
.
1938
Sep
;
31
(
11
):
1317
36
.
[PubMed]
0035-9157
10.
Harris
JP
,
Alexander
TH
.
Current-day prevalence of Ménière’s syndrome
.
Audiol Neurotol
.
2010
;
15
(
5
):
318
22
.
[PubMed]
1420-3030
11.
Havia
M
,
Kentala
E
,
Pyykkö
I
.
Prevalence of Menière’s disease in general population of Southern Finland
.
Otolaryngol Head Neck Surg
.
2005
Nov
;
133
(
5
):
762
8
.
[PubMed]
0194-5998
12.
Health Insurance Review & Assessment Service
.
Statistics yearbook of health insurance
.
2016
. Availabe from: http://hira.kr
13.
Health Insurance Review & Assessment Service
.
Main statistics of medical expenses
.
2017
. Availabe from: http://hira.kr
14.
Health Insurance Review & Assessment Service
.
Main statistics of medical expenses
.
2018
. Availabe from: http://hira.kr
15.
Herbert
I
,
Nolte
E
,
Eichhorn
T
.
[Weather status and incidence of idiopathic facial nerve paralyses, vestibular disorders, Menière’s attacks and sudden deafness]
.
Laryngol Rhinol Otol (Stuttg)
.
1987
May
;
66
(
5
):
249
50
.
[PubMed]
0340-1588
16.
Hong
SK
,
Koh
EK
,
Kim
KS
,
Park
KH
,
Park
HJ
,
Ahn
SK
, et al
Multicenter study on the treatment pattern of Meniere’s disease in Korea
.
J Korean Bal Soc.
2008
;
7
(
2
):
174
81
.
17.
Kang
SY
,
Song
WJ
,
Cho
SH
,
Chang
YS
.
Time trends of the prevalence of allergic diseases in Korea: A systematic literature review
.
Asia Pac Allergy
.
2018
Jan
;
8
(
1
):
e8
.
[PubMed]
2233-8276
18.
Kim
SH
,
Kim
SJ
,
Im
H
,
Kim
TH
,
Song
JJ
,
Chae
SW
.
A Trend in Sudden Sensorineural Hearing Loss: Data from a Population-Based Study
.
Audiol Neurotol
.
2017
;
22
(
6
):
311
6
.
[PubMed]
1420-3030
19.
Kirby
SE
,
Yardley
L
.
Physical and psychological triggers for attacks in Ménière’s disease: the patient perspective
.
Psychother Psychosom
.
2012
;
81
(
6
):
396
8
.
[PubMed]
0033-3190
20.
Korea Meteorological Administration [internet]. Portal for Korea meteorological open data. Available from: https://data.kma.go.kr
21.
Korea Pharmaceutical Information Center [internet]. Available from: http://health.kr
22.
Korean Statistical Information Service [internet]. Available from: http://kosis.kr
23.
Lopez-Escamez
JA
,
Carey
J
,
Chung
WH
,
Goebel
JA
,
Magnusson
M
,
Mandalà
M
, et al;
Classification Committee of the Barany Society
;
Japan Society for Equilibrium Research
;
European Academy of Otology and Neurotology (EAONO)
;
Equilibrium Committee of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS)
;
Korean Balance Society
.
Diagnostic criteria for Menière’s disease
.
J Vestib Res
.
2015
;
25
(
1
):
1
7
.
[PubMed]
0957-4271
24.
Ministry of Health and Welfare
,
Republic of Korea.
Status of medical service use 2017.
2018
.
25.
Ministry of Health and Welfare
.
Republic of Korea.
Health and welfare statistical year book 2018.
2018
. Vol. 64
26.
Nakashima
T
,
Pyykkö
I
,
Arroll
MA
,
Casselbrant
ML
,
Foster
CA
,
Manzoor
NF
, et al
Meniere’s disease
.
Nat Rev Dis Primers
.
2016
May
;
2
(
1
):
16028
.
[PubMed]
2056-676X
27.
Nevoux
J
,
Franco-Vidal
V
,
Bouccara
D
,
Parietti-Winkler
C
,
Uziel
A
,
Chays
A
, et al;
Groupe de Travail de la SFORL
;
Guidelines of the French Otorhinolaryngology-Head and Neck Surgery Society (SFORL)
.
Diagnostic and therapeutic strategy in Menière’s disease
.
Eur Ann Otorhinolaryngol Head Neck Dis
.
2017
Dec
;
134
(
6
):
441
4
.
[PubMed]
1879-7296
28.
Nevoux
J
,
Barbara
M
,
Dornhoffer
J
,
Gibson
W
,
Kitahara
T
,
Darrouzet
V
.
International consensus (ICON) on treatment of Ménière’s disease
.
Eur Ann Otorhinolaryngol Head Neck Dis
.
2018
Feb
;
135
(
1
1S
):
S29
32
.
[PubMed]
1879-7296
29.
Pereira
AB
,
Almeida
LA
,
Pereira
NG
,
Menezes
PA
,
Felipe
L
,
Volpe
FM
.
Seasonality of dizziness and vertigo in a tropical region
.
Chronobiol Int
.
2015
Jun
;
32
(
5
):
585
90
.
[PubMed]
0742-0528
30.
Pieskä
T
,
Kotimäki
J
,
Männikkö
M
,
Sorri
M
,
Hietikko
E
.
Concomitant diseases and their effect on disease prognosis in Meniere’s disease: diabetes mellitus identified as a negative prognostic factor
.
Acta Otolaryngol
.
2018
Jan
;
138
(
1
):
36
40
.
[PubMed]
0001-6489
31.
Radtke
A
,
von Brevern
M
,
Feldmann
M
,
Lezius
F
,
Ziese
T
,
Lempert
T
, et al
Screening for Menière’s disease in the general population - the needle in the haystack
.
Acta Otolaryngol
.
2008
Mar
;
128
(
3
):
272
6
.
[PubMed]
0001-6489
32.
Schmidt
W
,
Sarran
C
,
Ronan
N
,
Barrett
G
,
Whinney
DJ
,
Fleming
LE
, et al
The weather and Ménière’s disease: a longitudinal analysis in the UK
.
Otol Neurotol
.
2017
Feb
;
38
(
2
):
225
33
.
[PubMed]
1531-7129
33.
Shojaku
H
,
Watanabe
Y
,
Fujisaka
M
,
Tsubota
M
,
Kobayashi
K
,
Yasumura
S
, et al
Epidemiologic characteristics of definite Ménière’s disease in Japan. A long-term survey of Toyama and Niigata prefectures
.
ORL J Otorhinolaryngol Relat Spec
.
2005
;
67
(
5
):
305
9
.
[PubMed]
0301-1569
34.
Thygesen
LC
,
Ersbøll
AK
.
When the entire population is the sample: strengths and limitations in register-based epidemiology
.
Eur J Epidemiol
.
2014
Aug
;
29
(
8
):
551
8
.
[PubMed]
0393-2990
35.
Tyrrell
JS
,
Whinney
DJ
,
Ukoumunne
OC
,
Fleming
LE
,
Osborne
NJ
.
Prevalence, associated factors, and comorbid conditions for Ménière’s disease
.
Ear Hear
.
2014
Jul-Aug
;
35
(
4
):
e162
9
.
[PubMed]
0196-0202
36.
Yancy
CW
,
Jessup
M
,
Bozkurt
B
,
Butler
J
,
Casey
DE
 Jr
,
Colvin
MM
, et al;
WRITING COMMITTEE MEMBERS
.
2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America
.
Circulation
.
2016
Sep
;
134
(
13
):
e282
93
.
[PubMed]
1524-4539
37.
Yoo
B
,
Park
Y
,
Park
K
,
Kim
H
.
A 9-year trend in the prevalence of allergic disease based on national health insurance data
.
J Prev Med Public Health
.
2015
Nov
;
48
(
6
):
301
9
.
[PubMed]
1975-8375
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