The purpose of this study was to determine the acoustic transfer characteristics of cartilage for optimal cartilage myringoplasty. In order to do so, we developed a cartilage plate/tympanic membrane-coupled model using finite element analysis. Cartilage specimens of the tragus were obtained from fresh human cadavers, and the parameters of the tragus were determined by curve fitting and cross-calibration. A cartilage plate was used to repair an eardrum perforation, and the new coupled tympanic membrane-cartilage complex was loaded into our 3-dimensional biomechanical model of the middle ear for analysis. Our results show that first the β-damping value of the cartilage plate depends on frequency. The value of β damping was close to 3 × 10–4 s at lower frequencies and 5 × 10–6 s at higher frequencies. Secondly, reducing cartilage thickness leads to an improvement of its acoustic transfer qualities. From an acoustics point of view, the 0.1- to 0.2-mm cartilage plate seems to be most preferable with regard to tympanic membrane vibration. Furthermore, thicknesses of 0.2 mm at lower frequencies and 0.1 mm at higher frequencies were regarded as good compromises between sufficient mechanical stability and low acoustic transfer loss.

1.
Beer HJ, Bornitz M, Harstke HJ, Schmidt R, Hofmann G, Vogel U: Modelling of components of the human middle ear and simulation of their dynamic behavior. Audiol Neurootol 1999;4:156–162.
2.
Dornhoffer JL: Surgical management of the atelectatic ear. Am J Otol 2000;21:315–321.
3.
Funnell WR, Khanna SM, Decramer WF: On the degree of rigidity of the manubrium in a finite element model of the cat ear drum. J Acoust Soc Am 1992;91:2082–2090.
4.
Gan RZ, Sun Q, Robert KD Jr, Chang KH, Dormer KJ: Three-dimensional modeling of middle ear biomechanics and its applications. Otol Neurotol 2002;23:271–280.
5.
Heermann HJ, Heermann H, Kopstein E: Fascia and cartilage palisade tympanoplasty: nine years experience. Arch Otolaryngol 1970;91:229–240.
6.
Hildman H, Luckhaupt H, Schmelzer A: Die Verwendung von Knorpel in der Mittelohrchirurgie. HNO 1996;44:597–603.
7.
Huber A, Ball G, Asai M, Goode R: The vibration pattern of the tympanic membrane after placement of a total ossicular replacement prosthesis. Proc Int Workshop Middle Ear Mech Res Otosurg, Dresden, 1997, pp 219–222.
8.
Kerr AG, Byrne JE, Smyth GD: Cartilage homografts in the middle ear: a long-term histologic study. J Laryngol Otol 1973;87:1193–1199.
9.
Lee CF, Chen PR, Lee WJ, Chen JH, Liu TC: Three-dimensional reconstruction and modeling of middle ear biomechanics by high-resolution computed tomography and finite element analysis. Laryngoscope 2006;116:711–716.
10.
Moore GY: Revision tympanoplasty utilizing fossa triangularis cartilage. Laryngoscope 2002;112:1543–1554.
11.
Mürbe D, Zahnert T, Bornitz M, Hüttenbrink KB: Acoustic properties of different cartilage reconstruction techniques of the tympanic membrane. Laryngoscope 2002;112:1769–1776.
12.
Nishihara S, Aritomo H, Goode RL: Effect of changes in mass on middle ear function. Otolaryngol Head Neck Surg 1993;109:899–910.
13.
Overbosch HC: Homograft myringoplasty with microsliced septal cartilage. Pract Otorhinolaryngol (Basel) 1971;33:356–357.
14.
Salen B: Myringoplasty using septum cartilage. Acta Otolaryngol Suppl 1988:82–91.
15.
Shea MC, Glasscock ME: Tragal cartilage as ossicular substitute. Arch Otolaryngol 1967;86:308–317.
16.
Sun Q, Gan RZ, Chang KH, Dormer KJ: Computer-integrated finite element modeling of human middle ear. Biomech Model Mechanobiol 2002;1:109–122.
17.
Woo SLY, Akeson WH, Jemmot GF: Measurement of nonhomogenous, directional mechanical properties of articular cartilage in tension. J Biomech 1976;9:785–791.
18.
Wada H, Yokobori AT, Kakizaki T, Kobayashi T: Mechanical properties of ossicles and prosthesis. Oto Jpn 1996;6:42–46.
19.
Zahnert T, Hüttenrink KB, Mürbe D, Bornitz M: Experimental investigation of the use of cartilage in tympanic membrane reconstruction. Am J Otol 2000;21:322–328.
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