Background: Figs are a rich source of soluble fiber. We evaluated the effect of consuming dried California Mission figs on serum lipids in hyperlipidemic adults. Methods: In a crossover trial men and women aged 30–75 years with elevated low-density lipoprotein cholesterol (100–189 mg/dl) were randomized to add dried California Mission figs (120 g/day) to their usual diet for 5 weeks or eat their usual diet for 5 weeks, then crossed over to the other condition for another 5 weeks. Six 24-hour dietary recalls were obtained. Results: Low- and high-density lipoprotein cholesterol and triglyceride concentrations did not differ between usual and figs-added diets (Bonferroni-corrected p > 0.017), while total cholesterol tended to increase with fig consumption (p = 0.02). Total cholesterol increased in participants (n = 41) randomized to usual followed by figs-added diet (p = 0.01), but remained unchanged in subjects (n = 42) who started with figs-added followed by usual diet (p = 0.4). During the figs-added diet, soluble fiber intake was 12.6 ± 3.7 versus 8.2 ± 4.1 g/day in the usual diet (p < 0.0001). Sugar intake increased from 23.4 ± 6.5 to 32.2 ± 6.3% of kcal in the figs-added diet (p < 0.0001). Body weight did not change (p = 0.08). Conclusions: Daily consumption of figs did not reduce low-density lipoprotein cholesterol. Triglyceride concentrations were not significantly changed despite an increase in sugar intake.

Keywords:
Dietary intake, Lipids, Figs, Dietary fiber, Hypercholesterolemia
1.
Ross R: Atherosclerosis: an inflammatory disease. N Engl J Med 1990;340:115–126.
2.
Behall KM, Schofield DJ, Hallfrisch J: Effect of β-glucan level in oat fiber extracts on blood lipids in men and women. J Am Clin Nutr 1997;16:46–51.
3.
Brown L, Rosner B, Willett WW, Sacks FM: Cholesterol-lowering effects of dietary fiber: a meta-analysis. J Am Clin Nutr 1999;69:30–42.
4.
Lichtenstein AH, Appel LJ, Brands M, Carnethon M, Daniels S, Franch HA, Franklin B, Kris-Etherton P, Harris WS, Howard B, Karanja N, Lefevre M, Rudel L, Sacks F, Van Holrn L, Winston M, Wylie-Rosett J: Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation 2006;114:82–96.
5.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001;285:2486–2497.
6.
Rimm EB, Ascherio A, Giovannucci E, Spiegelman D, Stampfer MJ, Willett WC: Vegetable, fruit, and cereal fiber intake and risk of coronary heart disease. JAMA 1996;275:447–451.
7.
Vinson J, Zubik L, Bose P, Samman N, Proch J: Dried fruits: excellent in vitro and in vivo antioxidants. J Am Coll Nutr 2005;24:44–50.
8.
Marlett JA, Cheung TF: Database and quick methods of assessing typical dietary fiber intakes using data for 228 commonly consumed foods. J Am Diet Assoc 1997;10:1139–1148, 1151; quiz 1149–1150.
9.
Vinson JA: The functional food properties of figs. Cereal Food World 1999;44:82–87.
10.
Marlett JA, Cheung TF: Database and quick methods of assessing typical dietary fiber intakes using data for 228 commonly consumed foods. J Am Diet Assoc 1997;97:1139–1151.
11.
Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Sato M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H: Influence of fat and carbohydrate proportions on the metabolic profile in patients with type 2 diabetes: a meta analysis. Diabetes Care 2009;32:959–965.
12.
Dietschy J, Turley S, Spady D: Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 1993;34:1637–1659.
13.
Marques E, Carvalho J,Soares JMC, Marques F, Mota J: Effects of resistance and multicomponent exercise on lipids profiles of older women. Maturitas 2009;63:84–88.
14.
Miller T, Abdel-Maksoud MF, Crane LA, Marcus AC, Byers TE: Effects of social approval bias on self-reported fruit and vegetable consumption: a randomized controlled trial. Nutr J 2008;7:18.
15.
Institute of Medicine: Food and Nutrition Board. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients). Washington, National Academy Press, 2005.
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2011
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