A chronic vitamin B6 deficiency in rats resulted in a non-specific increase (44–51 %) in the in vitro intestinal uptake of both essential (Ca and Zn) and non-essential toxic metal (Cd) ions, whereas an acute B6-deficient state only affected the Zn uptake rate. In vitamin B1 -deficient animals, a specific decrease (30–32%) was observed in Ca and Zn uptake with a 59% increase in the intestinal uptake of Cd. These altered metal ion uptake rates were probably not a result of hormonal disturbances due to the vitamin-deficient states.

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