...Elias John Elenjickal; Christoforos K. Travlos; Pedro Marques; Thomas A. Mavrakanas Background: Both atrial fibrillation and venous thromboembolism (VTE) are highly prevalent among patients with chronic kidney disease (CKD). Until recently, warfarin was the most commonly prescribed oral...

...-stage kidney disease (ESKD) population. In this observational cohort study, we examined whether DOACs are a safe alternative to warfarin across CKD stages for a variety of anticoagulation indications. Methods: Individuals on DOACs or warfarin were identified from OptumLabs® Data Warehouse (OLDW...

...Theepika Rajkumar; Jeffrey Wong; Michael Harvey; Lachlan Weidersehn; Laura Surmon; Angela Makris Background: Haemorrhagic and thrombotic complications are common in dialysis patients on warfarin; thus, accurate international normalized ratio (INR) monitoring is critical. For expediency and patient...

... morbidity and mortality. Warfarin use is an identified risk factor. Twenty patients with ESRD on dialysis with calciphylaxis who were treated with apixaban for indications of deep vein thrombosis or atrial fibrillation were identified. There were no reports of thrombosis. Three individuals experienced...

...Mark C. Lin; Elani Streja; Melissa Soohoo; Medhat Hanna; Javad Savoj; Kamyar Kalantar-Zadeh; Wei Ling Lau Background: Controversy exists regarding the benefits and risks of warfarin therapy in chronic kidney disease (CKD) and end-stage renal disease (ESRD) patients. In this study, we assessed...

... evaluating the efficacy and safety of oral anticoagulants in this population, has been conducted so far. Observational research on the use of warfarin in patients on dialysis has shown conflicting results. This uncertainty is mirrored by the wide variations in warfarin prescription patterns across centers...

...Roberto S. Kalil; Peter J. Kaboli; Xin Liu; Mary Vaughan-Sarrazin Background: There is a higher risk of gastrointestinal (GI) bleeding in patients treated with dabigatran versus warfarin. We analyzed the impact of renal function on the relative risk of bleeding in patients converted to dabigatran...