...Shun Wu; Mengling Guo; Yudan Wang; Yilun Zhou; Liyuan Zhang; Yun Zhou; Yuanyuan Xing; Dong Sun; Xueqing Hu; Zhenmin Ruan; John Cijiang He; Hongqi Ren Introduction: Podocyte injury has been proven to be a major cause for poor renal outcomes after acute kidney injury (AKI). However, clinical trial...

... injury (AKI) requiring treatment with renal replacement therapy (RRT) is a common complication after admission to an intensive care unit (ICU) and is associated with significant morbidity and mortality. However, the prevalence of RRT use and the associated outcomes in critically patients across the globe...

... can identify subsets of patients with either similar outcomes or similar pathophysiology, respectively. Novel biomarkers can identify kidney injury in patients without consensus definition AKI (e.g., changes in creatinine or urine output) and can predict other adverse outcomes (e.g., severe consensus...

... Medical Center from 1992 to 2020, and crescents were seen in 26 (36%). Clinical, laboratory and histologic features at biopsy, and treatment and outcome (end-stage kidney disease, ESKD) were collected retrospectively. Data are presented as mean ± SD and a p value of <0.05 was significant. Results...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. COVID-19 Dialysis Outcomes Dialysis patients carry a higher risk of infectious complications, and from early reports...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fatigue Hemodialysis Branched-chain amino acids Tryptophan Outcomes National Institutes of Health (NIH...

... gabapentinoids for pain despite limited evidence supporting their use. We determined the prevalence of concomitant gabapentinoid and opioid prescriptions and evaluated their associations with outcomes among dialysis patients. Methods: We used the United States Renal Data System to identify patients treated...

...Hatem Ali; Ajay Sharma; Ahmed Halawa Background: This study aims to assess outcomes of interleukin-2 (IL-2) receptor blocker induction therapy on allograft and patients’ outcomes in standard risk recipients in the tacrolimus era, analysing data form the British Renal Transplant Registry. Methods...

... elderly as ≥65 years. This study aims to determine outcomes of induction immunosuppression in patients aged ≥75 years. Methods: A cohort of patients aged ≥75 years with a diagnosis of AAV between 2006 and 2018 was constructed from 2 centres. Follow-up was to 2 years or death. Analysis included...

...Zi-ning Liu; Zhao Cui; Ying-dong He; Yi-miao Zhang; Fang Wang; Xin Wang; Li-qiang Meng; Xu-yang Cheng; Gang Liu; Ming-hui Zhao Background: Primary membranous nephropathy (pMN) is less common in women of child-bearing age. The kidney risk factors to adverse maternal-fetal outcomes and the effects...

... risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety...

... revealing only a low risk of hyperkalemia. However, the effect of finerenone on renal and CV outcomes has not been investigated in long-term trials yet. Methods: The Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease -(FIDELIO-DKD) trial aims to assess the efficacy...

..., potentially as an appropriate adaptation to reduced glomerular filtration rate (GFR). We tested whether GFR-specific cutoffs for PTH1–84 and FGF-23 could better identify patients with inappropriately high PTH1–84 and FGF-23 for their degree of CKD and thereby improve prognostication of clinical outcomes...

... the frequency and severity of IDH is common. However, limited data exist to support this practice. This study sought to examine real-world efficacy of midodrine with respect to relevant clinical and hemodynamic outcomes. Methods: Here, we compared a variety of clinical and hemodynamic outcomes among adult...

...L. Parker Gregg; Maria Clarissa Tio; Xilong Li; Beverley Adams-Huet; James A. de Lemos; S. Susan Hedayati Background: Monocyte chemoattractant protein-1 -(MCP-1), a marker of inflammation and monocyte recruitment to atherosclerotic plaques, is associated with cardiovascular (CV) outcomes...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cardiovascular Kidney Outcomes P2Y 12 inhibitors Prevalence Chronic kidney disease (CKD) is one of the fastest growing chronic diseases and is the ninth leading...

... = 17,372). For recipients with evidence of a VTE posttransplant, we compared adverse clinical outcomes (death, graft loss) to matched (1:2) recipients without evidence of a VTE posttransplant. Results: During a median follow-up of 5.2 years, 388 (8.9%) recipients developed a VTE compared to 254 (1.5...

...Michelle M. O'Shaughnessy; Meghan A. Jobson; Katy Sims; Abigail L. Liberty; Patrick H. Nachman; William F. Pendergraft Background: Contemporary data regarding pregnancy outcomes in US patients with primary glomerular diseases are lacking. We aimed to report fetal and maternal outcomes among women...

... and performed instrumental variable analyses using propensity score adjusted and inverse probability of treatment-weighted modeling. [email protected] 28 02 2017 27 03 2017 27 4 2017 Outcomes Chronic kidney disease-mineral bone disorders Phosphorus binders Epidemiology...

... Rituximab Outcomes National Institutes of Health (NIH) 10.13039/100000002 Minimal-change glomerulopathy, which is a clinicopathologic diagnosis made in patients who usually present with the nephrotic syndrome, is defined histologically by the presence of normal glomeruli on light...