... reactive) and immunohistochemistry for myofibroblasts (α-smooth muscle actin; α-SMA) and macrophages (ED-1). Histomorphometrical analysis of collagen was performed with Sirius red staining, and collagen content was assessed by the amount of hydroxyproline. Cortex and medulla were analyzed separately...

... taken into account. Results: CD34+ spindle cells and SMA+ myofibroblasts were present in the renal interstitium in all but one case. In membranous, membranoproliferative and segmental-proliferative glomerulonephritis, CD34+ cells were seen in clusters, while in IgA nephropathy and in segmental and focal...

...Tim D. Hewitson; Marina Martic; Kristen J. Kelynack; Eugenia Pedagogos; Gavin J. Becker Interstitial myofibroblasts (MF) are cells with features of both smooth muscle cells and fibroblasts. They have been universally recognized in situations of tubulointerstitial injury, where their presence has...