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Keywords: Minicircle
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Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2019) 49 (5): 413–424.
Published Online: 12 April 2019
... minicircle (MC) technology, and evaluated its feasibility in therapeutic Klotho delivery. Methods: We engineered MC vectors to carry cassette sequences of Klotho and verified the self-production of Klotho protein from in HEK293T cells. We evaluated the location and persistence of delivered MC in vivo...