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1-20 of 91
Keywords: Inflammation
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Journal Articles
xiejia li, Abdul Rashid Qureshi, Mohamed E. Suliman, Olof Heimburger, Peter Barany, Peter Stenvinkel, Bengt Lindholm
Journal:
American Journal of Nephrology
Am J Nephrol (2023) 54 (7-8): 268–274.
Published Online: 24 May 2023
...-cause mortality risk in incident dialysis patients. These results suggest that IAR may provide useful prognostic information in patients with CKD. End-stage kidney disease Dialysis Inflammation Interleukin-6 Serum albumin Mortality The high morbidity and premature mortality in chronic...
Journal Articles
Journal:
American Journal of Nephrology
Am J Nephrol (2023) 54 (7-8): 337–348.
Published Online: 24 May 2023
... and immunohistochemistry. Results: Histology of IR/saline kidneys exhibited extensive necrosis of proximal tubular epithelial cells, as well as elevated levels of apoptosis markers and inflammation. In contrast, IR/LepA kidneys showed no signs of necrosis or inflammation with normal IL-6 and tall-like receptor 4 levels...
Journal Articles
Subject Area:
Nephrology
Anne M. Murray, Yelena Slinin, David E. Tupper, Sarah L. Pederson, Cynthia Davey, David T. Gilbertson, Paul Drawz, Ryan Mello, Allyson Hart, Kirsten L. Johansen, Scott Reule, Rebecca Rossom, David S. Knopman
Journal:
American Journal of Nephrology
Am J Nephrol (2022) 53 (6): 435–445.
Published Online: 28 April 2022
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic kidney disease Cognitive impairment Risk factors Inflammation Acidosis National Institutes of Health...
Journal Articles
Subject Area:
Nephrology
Ninad S. Chaudhary, Hemant K. Tiwari, Bertha A. Hidalgo, Nita A. Limdi, Richard J. Reynolds, Mary Cushman, Neil A. Zakai, Leslie Lange, Suzanne E. Judd, Cheryl A. Winkler, Jeffrey B. Kopp, Orlando M. Gutiérrez, Marguerite R. Irvin
Journal:
American Journal of Nephrology
Am J Nephrol (2022) 53 (2-3): 182–190.
Published Online: 31 January 2022
... ) nephropathy risk variants ( APOL1 ), unique to African-ancestry (African-American [AA]) populations, with systemic inflammation, a contributor to chronic kidney disease (CKD) and end-stage kidney disease (ESKD) is ill-defined. This study aimed to describe the role of inflammatory markers in the relationship...
Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2021) 52 (10-11): 771–787.
Published Online: 09 November 2021
... human physiology and functions as a counter-regulatory mechanism to mitigate immune responses during inflammation. Although the KP has been implicated in a variety of disorders including Huntington’s disease, seizures, cardiovascular disease, and osteoporosis, its role in renal diseases is seldom...
Journal Articles
Subject Area:
Nephrology
Wenjin Liu, Lulu Wang, Xiurong Li, Chaoqing Gao, Jianmei Zhou, Jiajun Zhou, Liang Wang, Zhuxing Sun, Hong Chu, Wei Fan, Youwei Bai, Junwei Yang
Journal:
American Journal of Nephrology
Am J Nephrol (2021) 52 (9): 725–734.
Published Online: 10 September 2021
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. C-X-C motif chemokine ligand Dialysis Inflammation Biomarker Kidney disease...
Journal Articles
Subject Area:
Nephrology
Glenn M. Chertow, Gerald B. Appel, Sharon Andreoli, Sripal Bangalore, Geoffrey A. Block, Arlene B. Chapman, Melanie P. Chin, Keisha L. Gibson, Angie Goldsberry, Kazumoto Iijima, Lesley A. Inker, Bertrand Knebelmann, Laura H. Mariani, Colin J. Meyer, Kandai Nozu, Megan O’Grady, Arnold L. Silva, Peter Stenvinkel, Roser Torra, Bradley A. Warady, Pablo E. Pergola
Journal:
American Journal of Nephrology
Am J Nephrol (2021) 52 (3): 180–189.
Published Online: 31 March 2021
..., instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. Alport syndrome Chronic kidney disease Inflammation Alport syndrome is a rare and serious genetic disease that affects as many as 60,000 persons in the USA and an estimated...
Journal Articles
Subject Area:
Nephrology
Ashutosh M. Shukla, Mark S. Segal, Carl J. Pepine, Alfred K. Cheung, Jonathan Shuster, Rajesh Mohandas, Wanda M. Martinez, Jeremy J. Flint, Sudhir V. Shah
Journal:
American Journal of Nephrology
Am J Nephrol (2021) 52 (1): 36–44.
Published Online: 26 February 2021
...Ashutosh M. Shukla; Mark S. Segal; Carl J. Pepine; Alfred K. Cheung; Jonathan Shuster; Rajesh Mohandas; Wanda M. Martinez; Jeremy J. Flint; Sudhir V. Shah Introduction: Atherosclerosis, inflammation, and vascular stiffness are prominent interrelated risk factors contributing to the high incidence...
Journal Articles
Subject Area:
Nephrology
Luis Bravo González-Blas, Leticia García-Gago, Daniela Astudillo-Jarrín, Catuxa Rodríguez-Magariños, Antía López-Iglesias, Teresa García Falcón, Ana Rodríguez-Carmona, Miguel Pérez Fontán
Journal:
American Journal of Nephrology
Am J Nephrol (2020) 51 (1): 54–64.
Published Online: 06 December 2019
...) did not appear to influence the risk pattern associated with lower serum sodium levels. Conclusions: Our results suggest that hyponatremia performs as a consistent correlate of the risk of mortality mainly in PD patients manifesting direct or indirect signs of inflammation and wasting, while...
Journal Articles
Subject Area:
Nephrology
Xin Li, Ming Wu, Limin Chen, Junyan Lu, Guo Li, Lili Fu, Na Qi, Ye Lin, Zhongya Sun, Xueqi Wang, Hao Zhang, Jingqiu Liu, Hualiang Jiang, Lin Li, Chang-Lin Mei, Cheng Luo
Journal:
American Journal of Nephrology
Am J Nephrol (2020) 51 (1): 1–10.
Published Online: 06 November 2019
...Xin Li; Ming Wu; Limin Chen; Junyan Lu; Guo Li; Lili Fu; Na Qi; Ye Lin; Zhongya Sun; Xueqi Wang; Hao Zhang; Jingqiu Liu; Hualiang Jiang; Lin Li; Chang-Lin Mei; Cheng Luo Background: Inflammation plays an important role in polycystic kidney disease (PKD). Cordyceps sinensis, a prized -Chinese...
Journal Articles
Subject Area:
Nephrology
L. Parker Gregg, Maria Clarissa Tio, Xilong Li, Beverley Adams-Huet, James A. de Lemos, S. Susan Hedayati
Journal:
American Journal of Nephrology
Am J Nephrol (2018) 47 (6): 395–405.
Published Online: 06 June 2018
...L. Parker Gregg; Maria Clarissa Tio; Xilong Li; Beverley Adams-Huet; James A. de Lemos; S. Susan Hedayati Background: Monocyte chemoattractant protein-1 -(MCP-1), a marker of inflammation and monocyte recruitment to atherosclerotic plaques, is associated with cardiovascular (CV) outcomes...
Journal Articles
Subject Area:
Nephrology
Jin Ho Hwang, Seung Hee Yang, Yong Chul Kim, Jin Hyuk Kim, Jung Nam An, Kyung Chul Moon, Yun Kyu Oh, Jae Yoon Park, Dong Ki Kim, Yon Su Kim, Chun Soo Lim, Jung Pyo Lee
Journal:
American Journal of Nephrology
Am J Nephrol (2018) 46 (6): 501–517.
Published Online: 21 December 2017
... changes in the obstructed kidney of wild-type mice, whereas global knockout of periostin reduced fibrosis induced by UUO and improved kidney structure. Fibrosis- and inflammation-related mRNA were significantly induced in the wild-type mice and were decreased in the Postn-KO mice. Additionally, α-smooth...
Journal Articles
Subject Area:
Nephrology
Christina Catabay, Yoshitsugu Obi, Elani Streja, Melissa Soohoo, Christina Park, Connie M. Rhee, Csaba P. Kovesdy, Takayuki Hamano, Kamyar Kalantar-Zadeh
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 46 (5): 408–416.
Published Online: 07 November 2017
... prognostication markers. These are associated with malnutrition and inflammation, and hence, may provide benefit in predicting mortality among hemodialysis patients. Methods: Among 108,548 incident hemodialysis patients in a large U.S. dialysis organization (2007–2011), we compared the mortality predictability...
Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 46 (2): 131–138.
Published Online: 20 July 2017
...Xia Xiao; Chunyang Du; Zhe Yan; Yonghong Shi; Huijun Duan; Yunzhuo Ren Background: Inflammation plays a crucial role in renal interstitial fibrosis, the pathway of chronic kidney diseases. Necroptosis is a novel form of regulated cell death, which plays a potential role in inflammation and renal...
Journal Articles
Subject Area:
Nephrology
Farsad Afshinnia, Lixia Zeng, Jaeman Byun, Crystal A. Gadegbeku, Maria Chiara Magnone, Carl Whatling, Barbara Valastro, Matthias Kretzler, Subramaniam Pennathur, Michigan Kidney Translational Core CPROBE Investigator Group
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 46 (1): 73–81.
Published Online: 01 July 2017
..., instructions or products referred to in the content or advertisements. Oxidative stress Chronic renal failure Cardiovascular Biomarkers Inflammation National Institutes of Health (NIH) 10.13039/100000002 Growing body of evidence reveals higher rate of cardiovascular morbidity...
Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 45 (5): 452–459.
Published Online: 03 May 2017
... revealed no significant difference in both groups. Conclusion: Febuxostat appears to improve hyperuricemia and endothelial dysfunction and ameliorate inflammation in hemodialysis patients with no safety concerns. [email protected] 24 01 2017 3 03 2017 3 5 2017 ©...
Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 45 (5): 389–399.
Published Online: 29 March 2017
... Inflammation Acute kidney injury (AKI) is a common clinical symptom with high mortality and morbidity [ 1,2 ]. Ischemia-reperfusion (IR) injury (IRI) is one of the major causes of AKI [ 3,4 ]. Inflammation, which engages in both innate immune system and adaptive immune system, is now believed to play...
Journal Articles
Subject Area:
Nephrology
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 45 (4): 310–319.
Published Online: 25 February 2017
...Ivano Baragetti; Basset El Essawy; Paolo Fiorina Background: Despite the stable incidence of end-stage renal disease (ESRD), it continues to be associated with an unacceptably high cardiovascular risk. Summary: ESRD is characterized by enhanced oxidative stress and severe inflammation, which boost...
Journal Articles
Journal:
American Journal of Nephrology
Am J Nephrol (2016) 44 (5): 354–367.
Published Online: 22 October 2016
... lead to structural and functional changes of mesangial cells, proximal tubular cells and podocytes and a gradual reduction in nephron number [ 18,19,20 ]. In addition, increased systemic and renal oxidative stress, increased generation of inflammatory cytokines from adipose tissues, renal inflammation...
Journal Articles
Subject Area:
Nephrology
Carin Wallquist, Ladan Mansouri, Mattias Norrbäck, Britta Hylander, Stefan H. Jacobson, Joachim Lundahl
Journal:
American Journal of Nephrology
Am J Nephrol (2016) 44 (4): 268–275.
Published Online: 08 September 2016
... as oxidative metabolism capacity was measured with flow cytometry in 108 CKD patients and healthy controls. Soluble markers of inflammation, such as cytokines, were analyzed using the Milliplex technique. Results: Patients showed significantly lower CD11b expression after stimulation during the 3rd (p = 0.002...
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