... time point of the experiment the ratio of LV weight to BW (LV/BW) was significantly higher in SNX animals (fig. 3 ), as a result of a lower BW in the SNX group. Myocardial infarction Renal failure Remodeling Hypertrophy © 2010 S. Karger AG, Basel 2010 Copyright / Drug Dosage...

... nephropathy (DN). Resveratrol, an agent that activates AMPK, may have the potential to protect against the development of DN. This study was designed to investigate the therapeutic effects of resveratrol on renal hypertrophy in early-stage diabetes and the underlying mechanisms. Method: Molecular...

... consists mostly of an increase in the glomerular filtration rate of the remaining kidney, and hypertrophy of cells comprising the nephron, mainly of the proximal tubular cells. Although the phenomenon of single kidney hypertrophy has been known for the past thousand years and despite intensive research...

... during the initial stages of diabetic nephropathy, including sodium retention and renal hypertrophy. We tested the hypothesis that pentoxifylline (PTF), an agent that inhibits TNF synthesis, could prevent sodium retention and renal hypertrophy during diabetes. Methods: Proximal and distal tubule TNF...

...Nina M. Newton; Leon G. Fine Histological examination of the kidney was well under way by the mid-19th century. Pathological changes noted to be present in Bright’s disease gave rise to considerable debate in the literature of the time. Toynbee was perhaps the first to note medial hypertrophy...