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Keywords: Hypersensitivity reaction
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Journal Articles
Subject Area:
Nephrology
Julia Cordelia Hempel, Felix Poppelaars, Mariana Gaya da Costa, Casper F.M. Franssen, Thomas P.G. de Vlaam, Mohamed R. Daha, Stefan P. Berger, Marc A.J. Seelen, Carlo A.J.M. Gaillard
Journal:
American Journal of Nephrology
Am J Nephrol (2017) 45 (1): 49–59.
Published Online: 26 November 2016
... hemodialysis (HD). All IV iron preparations carry a risk of causing hypersensitivity reactions. However, the pathophysiological mechanism is poorly understood. We hypothesize that a relevant number of these reactions are mediated by complement activation, resulting in a pseudo-anaphylactic clinical picture...