..., instructions or products referred to in the content or advertisements. 2025 Cancer Glomerular disease Glomerulonephritis Paraneoplastic Kidney health is often impacted during malignancy, contributing to increased morbidity and mortality and potentially affecting oncologic treatment. Cancer...

... multiple systems including the kidney. Currently, limited data are available to guide treatment of acute kidney injury secondary to ICI use (ICI-AKI) due to tubulointerstitial nephritis or glomerulonephritis. Another huge obstacle is the safety of resuming ICI following an episode of ICI-AKI. Summary...

... testing that will enable precision medicine in kidney care. Genomic test Glomerulonephritis Implementation science Rare kidney disease The joint international consensus statement by the International Society of Nephrology, European Renal Association and American Society of Nephrology...

... recruitment and the relevance of its two corresponding chemokines CCL17 and CCL22 have not been studied in immune-mediated crescentic glomerulonephritis (cGN). Methods: Utilizing the single-cell RNA sequencing (scRNAseq) data in analyzing leukocytes isolated from both human and murine nephritic kidneys, we...

... Glomerulonephritis IgA nephropathy Mast cell Lymphocytes Pathology Immunoglobulin A (IgA) nephropathy, which is characterized by glomerular mesangial IgA deposition, is the most common primary glomerulonephritis globally [ 1, 2 ]. A systematic review of kidney biopsy-based studies in multiple countries...

... Crescents End-stage kidney disease Glomerulonephritis IgA nephropathy Outcomes IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and a leading cause of chronic kidney disease and end-stage kidney disease (ESKD) [ 1‒5 ]. While most patients with IgAN have an indolent...

...Xiao-Yan Jia; Hui-Yan Xu; Xiao-Yu Jia; Zhao Cui; Ming-Hui Zhao Introduction: Anti-glomerular basement membrane (GBM) disease is a rare but the most aggressive form of glomerulonephritis. To dissect the prognostic factors, we retrospectively analyzed the clinical features of a large cohort...

... [email protected] 25 09 2021 16 11 2021 29 12 2021 Glomerulonephritis IgA nephropathy Diagnostic biomarkers Lectins Glycomics IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide, characterized by persistent microscopic...

... to immune-complex glomerulonephritis (GN). However, OV infection in human kidney tissue has never been demonstrated. Herein, we evaluated the association of OV infection with biopsy-proven glomerular disease. Methods: This study was performed in adult patients who underwent kidney biopsy between July 2016...

... pathology. We intended to investigate the expression of TGF-β/Smad signaling in glomerulonephritis (GN) and to assess its role as risk factor for progression to chronic kidney disease (CKD). Methods: We evaluated the immunohistochemical expression of TGF-β1, phosphorylated Smad3 (pSmad3), and Smad7...

.... Glomerulonephritis IgA nephropathy Crescent Prognosis IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide, and 20–40% of patients will develop end-stage renal disease (ESRD) within 10–20 years [1]. The clinical course of IgAN and associated pathological lesions is highly...

... ]. Previous studies also suggested that outcomes might differ according to glomerular disease subtype, being poorer in women with membranoproliferative glomerulonephritis (MPGN) or focal segmental glomerulosclerosis (FSGS) than in those with IgA nephropathy (IgAN), membranous nephropathy (MN), or minimal...

.... National Institutes of Health (NIH) 10.13039/100000002 Crescentic glomerulonephritis Glomerulonephritis Graft function IgA nephropathy Kidney transplantation We reviewed the charts and original native kidney biopsies of 62 IgAN patients who received a transplant at our center...

...Amin Oomatia; Sarah M. Moran; Claire Kennedy; Rachel Sequeira; Sally Hamour; Aine Burns; Mark A. Little; Alan D. Salama Background: As renal biopsies are not routinely repeated to monitor treatment response in anti-neutrophil cytoplasm antibody (ANCA)-associated glomerulonephritis, serum creatinine...

...Cindy Zhou; Kristie Lou; Kiana Tatum; Jeremiah Funk; Jean Wu; Todd Bartkowiak; David Kagan; Yahuan Lou Background: Many types of glomerulonephritis (GN) undergo tandem connected phases: inflammation and fibrosis. Fibrosis in human GNs leads to irreversible end-stage disease. This study investigated...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glomerulonephritis Pediatrics...

...Ru Bu; Qian Li; Zhi-yu Duan; Jie Wu; Pu Chen; Xiang-mei Chen; Guang-yan Cai Backgrounds: IgA-dominant infection-associated glomerulonephritis (IgA-dominant IAGN) is a unique form of glomerulonephritis. There are numerous case reports in the literature. However, the risk factors, treatment approach...

...Michael L. Spinner; Lyndsey J. Bowman; Timothy A. Horwedel; Rowena B. Delos Santos; Christina L. Klein; Daniel C. Brennan Background/Aims: Post-renal transplant recurrent glomerulonephritis (GN) contributes to allograft loss. Rituximab treatment has been used in a multidose strategy with variable...

...Hajeong Lee; Dong Ki Kim; Kook-Hwan Oh; Kwon Wook Joo; Yon Su Kim; Dong-Wan Chae; Suhnggwon Kim; Ho Jun Chin Background: Previous epidemiological studies have focused on the prevalence of primary glomerulonephritis (GN), but few have explored long-term patient outcomes. This study was conducted...

.... Glomerulonephritis Biomarker Proteinuria Immunoglobulin A (IgA) nephropathy is the most common primary glomerulonephritis worldwide [ 1,2 ]. Following the initial mesangial deposition of IgA, there is progressive glomerulosclerosis and tubulointerstitial fibrosis in IgA nephropathy [ 3 ]. Available...