...) identifying risk loci for CKD, generally defined as estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m 2 , or GWAS for eGFR per se [ 2‒10 ]. However, many CKD patients in stage 3–5 have rather stable kidney function for years, and thus, the change in eGFR over time is more important than a cross...

... at the National Institutes of Health Clinical Center from 1995 to 2020 were retrospectively reviewed. For patients with more than one visit, the most recent renal function and urinalysis tests were analyzed. Estimated glomerular filtration rate (eGFR) was calculated using standard equations (i.e., Chronic Kidney...

... of the cross-sectional, community-based Tongren Health Care Study underwent a detailed medical and ophthalmological examination. We defined TD2 by a fasting plasma glucose concentration of ≥7.0 mmol/L or a medical history. CKD was classified as either reduced estimated glomerular filtration rate (eGFR...

... of the National Health and Nutrition Examination Survey (NHANES) database. Methods: A total of 28,239 adults aged ≥18 years who participated in the 2005–2014 NHANES were analyzed. CKD was defined as an estimated glomerular filtration rate <60 mL/min per 1.73 m 2 or urinary albumin/urine creatinine ratio ≥300...

...Jennifer Torres; Jennifer L. Ennis; Arlene B. Chapman; Rita L. McGill Introduction: Serum creatinine is the traditional biomarker for estimating glomerular filtration rate (eGFR). Cystatin C is an alternative biomarker for which estimating equations exist. The use of cystatin C testing...

... kidney dysfunction is associated with brain atrophy, especially in older adults. We used cross-sectional data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI), an NIH-funded multicenter longitudinal cohort study, to better understand the association between estimated glomerular filtration rate...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ethnic differences Cardiovascular disease Mortality Estimated glomerular filtration rate Urinary albumin-creatinine...

...Eugenia Wong; Shoshana H. Ballew; Natalie Daya; Junichi Ishigami; Casey M. Rebholz; Kunihiro Matsushita; Morgan E. Grams; Josef Coresh Introduction: Chronic kidney disease (CKD) risk staging is based on estimated glomerular filtration rate (eGFR) and albumin-creatinine ratio (ACR). However...

...: A prospective cohort study of 9,116 middle-aged nondiabetic -Japanese men without CKD nor proteinuria who were not taking antihypertensive medications nor urate-lowering medications at entry. CKD was defined as estimated glomerular filtration rate <60 mL/min/1.73 m 2 . We investigated the relationship...

... with the progression of proteinuria. Sleep Proteinuria Estimated glomerular filtration rate The crude HR for progression of proteinuria was 1.92 (95% CI 1.22–3.03), 1.23 (95% CI 1.09–1.39), and 1.18 (95% CI 1.00–1.39) for those with sleep duration < 4, 4–6, and > 8 h as compared to the reference...

... of this study was to evaluate the effect of preoperative renal function using either estimated-glomerular filtration rate (eGFR) derived using Chronic Kidney Disease-Epidemiology (CKD-EPI) or serum creatinine alone as a predictor for RRT after cardiac surgery. Methods: In this prospective cohort study, baseline...

... therapeutic groups at baseline. Compared with patients in the steroid group, patients in the CTX group showed better estimated glomerular filtration rate (eGFR) improvement (21.35 ± 19.63 vs. 2.72 ± 19.11 mL/min/1.73 m 2 , p = 0.006) but a similar decline in immunoglobulin G (IgG; 450 [interquartile range...

... with an estimated glomerular filtration rate (eGFR; calculated by the Chronic Kidney Disease Epidemiology Collaboration formula) <60 mL/min/1.73 m 2 were considered to have renal dysfunction. Results: Of 430 included patients, 249 (58%) were male and 181 (42%) were female, with a mean age of 55.9 ± 12.3 and 57.3...

... of deterioration of renal function. In line with these findings, it was found that elevated levels of copeptin at baseline were associated with greater decline in estimated glomerular filtration rate (eGFR) in patients with type 2 diabetes during long-term follow-up [ 8 ] as well as with the renal end point...

... of serum creatinine adjusted for age, sex and race and (in sensitivity analyses) estimated glomerular filtration rate (eGFR) using the MDRD formula. Outcome measures were changes in scores on 6 cognitive tests encompassing a range of cognitive functions, measured at 2-year intervals. Mixed-effects...

... to estimate the time to dialysis requirement. The rate of decline in the estimated glomerular filtration rate (eGFR) may be used to this end. Methods: This study compared the rate of eGFR decline prior to dialysis commencement between individuals with failing transplants and transplant-naïve patients...

... and cystatin C-based estimated glomerular filtration rate (eGFR) at 5-yearly intervals. The primary objective of the study was to determine the relationship of circulating OPG levels with 5- and 10-year renal decline. Results: At baseline, participants with elevated OPG above the median (≥2.2 ng/ml) had a 5.0...

... kidney disease Diabetes mellitus Estimated glomerular filtration rate Glycemic control Glycated hemoglobin HbA 1C Diabetic nephropathy is the leading cause of incident end-stage renal disease (ESRD) in Taiwan [ 1 ]. The incidence of chronic kidney disease (CKD) increases with increasing...

... the association between plasma endostatin, an endothelial-specific antiangiogenic factor, and chronic kidney disease (CKD). Methods: We compared plasma endostatin levels in 201 CKD patients and 201 controls. CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m 2 or presence...

...Robert N. Foley; Allan J. Collins Background/Aims: Although creatinine-based estimated glomerular filtration rate (eGFR) is associated with cardiovascular events, threshold values for optimum discrimination are unclear. We aimed to identify serum creatinine and eGFR thresholds of maximum...