... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Diabetic kidney disease Type 2 diabetes Biomarker Estimated glomerular filtration rate decline Due to the increasing incidence and prevalence of type 2...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Mineralocorticoid receptor antagonists Diabetic kidney disease Chronic kidney disease Meta-analysis...

...Christian W. Mende; Rohan Samarakoon; Paul J. Higgins Background: Diabetic kidney disease (DKD) is a common disorder with multiple serious clinical implications, including an increased risk of end-stage kidney disease (ESKD), cardiovascular complications, heart failure, onset or worsening...

... is calculated based on the geometric mean of CFB for participants with both baseline and postbaseline available values. CFB, change from baseline; LSM, least squares mean; SE, standard error. Biomarkers Diabetic kidney disease Glucagon-like peptide-1 receptor agonists Incretin therapy Chronic...

...). When categorizing the biomarkers into quartiles, the uppermost quartiles of NGAL and MCP-1 were associated with approximately a two-fold greater risk for death compared to the lowest quartiles (model 2; Table  4 ). Diabetic kidney disease Mortality KIM-1 NGAL MCP-1 YKL-40 IL-18 NIH...

... a promising avenue toward uncovering and establishing precise genetic diagnoses in various forms of kidney disease. Methods: Here, we set out to investigate the genetic basis of disease in nondiabetic kidney disease (NDKD) and diabetic kidney disease (DKD) patients by performing targeted NGS using a custom...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Visual Abstract Visual Abstract. Type 2 diabetes Kidney biopsy Diabetic kidney disease Diabetic...

... that glucagon-like peptide-1 receptor agonist can have a beneficial effect on the kidney. This trial aimed to assess the effects of exenatide on renal outcomes in patients with T2DM and diabetic kidney disease (DKD). Methods: We performed a randomized parallel study encompassing 4 general hospitals. T2DM...

... H3K27me3 Diabetic kidney disease Podocyte Clinical studies have shown that short periods of poor glycemic control might induce irreversible pathophysiological changes in several organs including the kidney, despite subsequent good glycemic control. This phenomenon is called metabolic memory [ 1...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Type 2 diabetes Diabetic kidney disease Cardiovascular disease Heart...

... is globally accepted as the main diagnostic criteria for diabetic kidney disease (DKD). Methods: In the present retrospective study, we evaluated data from an Italian cohort of 42 deceased diabetic donors (mainly with type 2 diabetes). Using the kidney biopsies obtained at the time of donation to evaluate...

... individuals with diabetic kidney disease (DKD), chronic kidney disease, type 2 diabetes (T2DM), and obese and healthy controls to determine if such biomarkers had the potential to classify kidney disease and predict patients at higher risk of renal function decline. Methods: A total of 242 participants...

...Manjula Darshi; Benjamin Van Espen; Kumar Sharma The development of new therapies for chronic diseases, such as diabetic kidney disease (DKD), will continue to be hampered by lack of sufficient biomarkers that will provide insights and will be responsive to treatment interventions. The recent...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic kidney disease African Americans Diabetes Diabetic kidney disease Genetics Reticulon 1 National Institutes of Health (NIH) 10.13039/100000002...

...Margaret K. Yu; Courtney Rees Lyles; Luis A. Bent-Shaw; Bessie A. Young; and the Pathways Authors Background/Aims: Women with diabetes experience a disproportionately greater burden of diabetic kidney disease (DKD) risk factors compared to men; however, sex-specific differences in DKD are not well...

...Li Zhou; Fei Liu; Xiao R. Huang; Fang Liu; Haiyong Chen; Arther C.K. Chung; Jianjian Shi; Lei Wei; Hui Y. Lan; Ping Fu Background: Although blockade of Rho kinase with pharmacologic inhibitors ameliorates renal fibrosis and diabetic kidney disease (DKD), the underlined mechanisms remain largely...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diabetic kidney disease Electron microscopy Histology Morphometry Podocyte National Institutes of Health (NIH) 10.13039/100000002 The role of the glomerular...