...Jennifer Torres; Jennifer L. Ennis; Arlene B. Chapman; Rita L. McGill Introduction: Serum creatinine is the traditional biomarker for estimating glomerular filtration rate (eGFR). Cystatin C is an alternative biomarker for which estimating equations exist. The use of cystatin C testing...

...Kozeta Miliku; Hanneke Bakker; Eiske M. Dorresteijn; Karlien Cransberg; Oscar H. Franco; Janine F. Felix; Vincent W.V. Jaddoe Background: Creatinine and cystatin C concentrations are commonly used to estimate glomerular filtration rate (eGFR) in clinical practice and epidemiological studies...

... I (TnI), asymmetric dimethylarginine (ADMA), interleukin (IL)-6, high sensitivity C-reactive protein, fibroblast growth factor-23 (FGF23), transforming growth factor-beta, 25-hydroxylvitamin D, and cystatin C (CysC). Results: The mean estimated glomerular filtration rate was 27 mL/min/1.73 m 2...

...Sandrine Lemoine; Marine Panaye; Caroline Pelletier; Chantal Bon; Laurent Juillard; Laurence Dubourg; Fitsum Guebre-egziabher Background: Cystatin C is considered an alternative to creatinine to estimate glomerular filtration rate (GFR). However, studies have reported that increased adiposity...

... right kidney main and arcuate artery resistive indices, those without ascites had higher FF and lower right kidney main and arcuate artery resistive indices. While cystatin C and β 2 -microglobulin performed better compared to Cr in estimating RPF, β-trace protein, β 2 -microglobulin, and SDMA...

...Aleksandra Kukla; Naim Issa; Scott Jackson; Richard Spong; Meredith C. Foster; Arthur J. Matas; Michael S. Mauer; John H. Eckfeldt; Hassan N. Ibrahim Background: The glomerular filtration rate (GFR) estimating equation incorporating both cystatin C and creatinine perform better than those using...

... obese individuals. Estimated GFR was calculated using the Modification of Diet in Renal Disease equation, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation using serum creatinine only, the CKD-EPI equation using serum cystatin C only and a recently derived equation that uses both...

... in the Fat Redistribution and Metabolic Change in HIV infection (FRAM) study, using multivariable linear regression. eGFR Cys and eGFR Cr were calculated from cystatin C and creatinine levels. Albuminuria was defined as a positive urine dipstick (≧1+) or urine albumin-to-creatinine ratio ≧30 mg/g. Common...

... in Renal Disease Study (MDRD) equation with 4 variables, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, the Cockcroft-Gault equation adjusted for body surface area and the MDRD equation with cystatin C. Performance was evaluated by mean bias, precision and accuracy. Results...

... based on creatinine and cystatin C. Methods: In the Cardiovascular Health Study, GFR changes in an elderly cohort were estimated from serum creatinine and cystatin C measured at baseline, year 3 and year 7 in 4,380 participants (age 72 ± 5 years at entry). Outcomes were mean eGFR decline, incident...

...Mohammad Akhtar Hossain; Mahmoud Emara; Hamdi El moselhi; Ahmed Shoker Background: Cystatin C (Cys C) is measured by particle-enhanced nephelometric immunoassay (PENIA), particle-enhanced turbidimetric immunoassay (PETIA) and ELISA. Aim: To determine differences among these methods. Method: 80...

...Ahmed Zahran; Amr El-Husseini; Ahmed Shoker Background: With the increasing knowledge that estimation of glomerular filtration rate (GFR) from serum creatinine (Scr) has limited value, researchers have developed new equations based on serum cystatin C (Cys C). Aim: To compare the performance...

...Stefan Herget-Rosenthal; Silke Trabold; Frank Pietruck; Marianne Holtmann; Thomas Philipp; Andreas Kribben Serum cystatin C, a cysteine proteinase inhibitor, has been proposed as a marker of glomerular filtration rate (GFR). Serum cystatin C, serum creatinine and creatinine clearance were measured...