... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alport syndrome Cardiovascular outcomes Collagen Genetics Kidney transplantation...

..., the increased levels of fibrotic markers, collagen and α-smooth muscle actin, in kidneys were significantly attenuated in KO-UUO versus WT-UUO mice. Meanwhile, kidney damage indices were remarkably attenuated in KO-UUO mice compared with WT-UUO mice. However, increased numbers of CD43+ and CD48+ cells, markers...

...Utpal Sen; Charu Munjal; Natia Qipshidze; Oluwasegun Abe; Riyad Gargoum; Suresh C. Tyagi Background/Aims: In this study we tested the hypothesis that H 2 S regulates collagen deposition, matrix metalloproteinases (MMP) and inflammatory molecules during hyperhomocysteinemia (HHcy) resulting...

... by morphology and alpha smooth muscle actin (α-SMA) immunostaining at the light and electron microscope level. Results were related to staining for interstitial leukocytes and collagen III. A control group consisted of 6 normal renal transplant donors from whom biopsy specimens were taken at the time...

... (Α-SMA) and compared with staining for monocytes (ED-1), collagen III, and bromodeoxyuridine incorporation. Histological changes included a focal lesion in E. coli infected animals. Interstitial Α-SMA staining was confined to spindle-shaped cells resembling myofibroblasts. The percent fractional area...

... ELISA kit as ours were 1.141 ± 0.291 and 1.280 ± 0.277 µg/ml in pre- and post-menopausal women, respectively [ 18 ]. Cardiovascular Chronic kidney disease Collagen Proteinuria Kidney disease Diabetic nephropathy The medical history was ascertained by a questionnaire. Height...

... reactive) and immunohistochemistry for myofibroblasts (α-smooth muscle actin; α-SMA) and macrophages (ED-1). Histomorphometrical analysis of collagen was performed with Sirius red staining, and collagen content was assessed by the amount of hydroxyproline. Cortex and medulla were analyzed separately...

...Josette Guillemant; Huyen-Tran Le; Annick Maria; Serge Guillemant Aim: The aim of the present study was to check whether a calcium oral load was able to inhibit bone resorption as assessed by urinary excretion of a new bone marker, type 1 collagen cross-linked C-telopeptide (CrossLaps TM...

... allow myofibroblasts to rearrange and contract interstitial collagenous proteins. Myofibroblasts from normal rat kidneys were grown in cell-populated collagen lattices to measure cell generated contraction. Following detachment of cell populated collagen lattices, myofibroblasts progressively contracted...