... settings, higher Uα1m is associated with acute kidney injury (AKI), progressive chronic kidney disease (CKD), cardiovascular (CV) events, and mortality. We investigated the associations of pre- and postoperative Uα1m concentrations with adverse outcomes after cardiac surgery. Methods: In 1,464 adults...

...George Drosos; Fotini Ampatzidou; Pantelis Sarafidis; Theodoros Karaiskos; Athanasios Madesis; Afroditi K. Boutou Background: Most studies evaluating predictors of renal replacement therapy (RRT) following cardiac surgery use arbitrary defined limits of preoperative serum creatinine. The aim...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute kidney injury Cardiac surgery Mortality Ventricular assist device RIFLE criteria National Institutes of Health (NIH) 10.13039/100000002 Acute...

...Matthew R. Weir; Solomon Aronson; Edwin G. Avery; Charles V. Pollack, Jr. Background/Aims: Patients who develop acute kidney injury (AKI) after cardiac surgery continue to have a high mortality rate. Although factors that predispose to postoperative renal dysfunction have been identified...

...Meyeon Park; Steven G. Coca; Sagar U. Nigwekar; Amit X. Garg; Susan Garwood; Chirag R. Parikh Background: Acute kidney injury (AKI) is common in patients undergoing cardiac surgery and is associated with a high rate of death, long-term sequelae and healthcare costs. We conducted a systematic review...

...Gebhard Wagener; Gina Gubitosa; Shuang Wang; Niels Borregaard; Mihwa Kim; H. Thomas Lee Background: Use of aprotinin has been associated with acute kidney injury after cardiac surgery. Neutrophil gelatinase-associated lipocalin (NGAL) is a novel, very sensitive marker for renal injury. Urinary NGAL...

... to 40% of adults following cardiac surgery [ 11,12,13 ]. Pathophysiologic mechanisms include diminished renal blood flow, loss of pulsatile flow, hypothermia, atheroembolism, and a generalized inflammatory response. A variety of clinical algorithms have been proposed for prediction of dialysis-requiring...