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Keywords: Bardoxolone methyl
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Am J Nephrol (2018) 47 (1): 40–47.
Published Online: 18 January 2018
..., and estimated glomerular filtration rate (eGFR) have been observed with bardoxolone methyl in 7 studies enrolling approximately 2,600 patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). The largest of these studies was Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease...
Journal Articles
Journal Articles
Journal Articles
Am J Nephrol (2013) 37 (3): 212–222.
Published Online: 28 February 2013
... (RAAS). Bardoxolone methyl, a synthetic triterpenoid that reduces oxidative stress and inflammation through Nrf2 activation and inhibition of NF-κB was previously shown to increase estimated glomerular filtration rate (eGFR) in patients with CKD associated with type 2 diabetes mellitus. To date...