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Keywords: Apoptosis
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Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2018) 46 (6): 501–517.
Published Online: 21 December 2017
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Anti-periostin antibody Apoptosis Chronic kidney disease  Fibrosis Inflammation Periostin Chronic kidney...
Journal Articles
Am J Nephrol (2016) 43 (3): 195–205.
Published Online: 14 April 2016
... activity, renal functioning, renal perfusion. The kidneys were allocated for histopathologic examinations and for the evaluation of renal hypoxia, intra-renal apoptosis and proliferation. Results: Contrary to the situation in untreated ischemic rats, renal perfusion was significantly improved in DNAse...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2015) 41 (6): 474–484.
Published Online: 25 July 2015
... and a significantly increased in vitro level of apoptosis in TECs incubated with plasma from CRS1 patients compared to HF and CTR (p < 0.01). In the CRS1 group, the mRNA expression of IL-6, IL-18 and NGAL resulted significantly higher in TECs incubated with CRS1 plasma compared with those incubated with plasma...
Journal Articles
Am J Nephrol (2015) 40 (6): 523–534.
Published Online: 07 January 2015
...Xiaoyan Bai; Jian Geng; Xiao Li; Fang Yang; Jianwei Tian Background/Aims: Vascular endothelial growth factor-A (VEGF-A) upregulation and podocyte apoptosis have been documented in diabetes. This study was designed to investigate whether inhibiting VEGF-A could ameliorate podocyte apoptosis...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2013) 38 (5): 430–444.
Published Online: 12 November 2013
...Yipeng Liu; Wei Liang; Qian Yang; Zhilong Ren; Xinghua Chen; Dongqing Zha; Pravin C. Singhal; Guohua Ding Background/Aims: The mechanism underlying angiotensin II (AngII)-promoted podocyte apoptosis has not been established. IQ domain GTPase-activating protein 1 (IQGAP1) is a scaffolding protein...
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2013) 38 (5): 368–378.
Published Online: 22 October 2013
...Sukru Ulusoy; Gulsum Ozkan; Mehmet Alkanat; Sevdegül Mungan; Esin Yuluğ; Asım Orem Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis, caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide synthase (eNOS) and the protective...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2013) 37 (3): 264–273.
Published Online: 13 March 2013
... ) was added 1 h before incubation with ioversol. Cell viability and permeability were determined by 3-(4,5-dimethyldiazol-2-yl)-2,5-diphenyl tetrazolium bromide and lactate dehydrogenase assay. Apoptosis was determined by flow cytometry. Intracellular Ca 2+ concentration ([Ca 2+ ] i ) and reactive oxygen...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2012) 35 (5): 456–465.
Published Online: 30 April 2012
...Jian-jun Gao; Guang-yan Cai; Yi-chun Ning; Lin Liu; Ju-rong Yang; Dan Dong; Bo Fu; Yang Lu; Shao-yuan Cui; Xiang-mei Chen Background: Nephrotoxicity of cisplatin limits its clinical application. Cisplatin-induced acute renal tubular epithelial cell apoptosis is one of the major mechanisms...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2011) 34 (5): 423–434.
Published Online: 21 September 2011
...) effacement and apoptosis, respectively. A mouse podocyte cell line was cultured and incubated with PAN. Immunoblot was used to examine the level of nestin expression both in vivo and in vitro. Enhanced green fluorescence protein-tagged plasmids containing nestin shRNA were transfected into the cultured...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2011) 34 (1): 77–86.
Published Online: 15 June 2011
..., induced apoptosis of aortic vascular smooth muscle cells and endothelial cells in vitro. However, the apoptotic effects of high phosphate (HP) level in human peritoneal mesothelial cells (HPMCs) are not known. Methods: To examine whether Pit-1 is expressed in HPMCs, we checked the Western blot assay...
Journal Articles
Journal Articles
Subject Area:
Nephrology
Am J Nephrol (2011) 33 (1): 49–59.
Published Online: 17 December 2010
... expression in Gly-AKI rats [ 3 ]. The same finding has been reported in other AKI etiologies [ 4 ]. Several p53-target genes are involved in cellular apoptosis and oxidative stress. Genes encoding proapoptotic proteins (e.g. Bax and PUMA) are transactivated [ 5 ], whereas prosurvival genes (e.g. Bcl-2...