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Tadao Akizawa
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Journal Articles

Long-Term Efficacy and Safety of Upacicalcet in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism: Open-Label 52-Week Study

Subject Area:
Nephrology
Takayuki Hamano, Fumihiko Koiwa, Yoshitaka Isaka, Keitaro Yokoyama, Masafumi Fukagawa, Yosuke Inagaki, Yukihisa S. Watanabe, Daisuke Honda, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol 1–15.
https://doi.org/10.1159/000541493
Published Online: 19 September 2024
View article titled, Long-Term Efficacy and Safety of Upacicalcet in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism: Open-Label 52-Week Study
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Journal Articles

A Comparative Study of Serum Phosphate and Related Parameters in Chronic Kidney Disease between the USA and Japan

Subject Area:
Nephrology
Naohiko Fujii, Takayuki Hamano, Jesse Y. Hsu, Enyu Imai, Tadao Akizawa, Kosaku Nitta, Tsuyoshi Watanabe, Satoshi Iimuro, Yasuo Ohashi, Seiichi Matsuo, Hirofumi Makino, Akira Hishida, Arnold B. Alper, Edward J. Horwitz, Chi-Yuan Hsu, Anna C. Porter, Myles Wolf, Wei Yang, Lisa Nessel, Harold I. Feldman
Journal: American Journal of Nephrology
Am J Nephrol (2022) 53 (2-3): 226–239.
https://doi.org/10.1159/000521386
Published Online: 28 February 2022
View article titled, A Comparative Study of Serum Phosphate and Related Parameters in Chronic Kidney Disease between the USA and Japan
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Journal Articles

Letter in Response to “HIF-Prolyl Hydroxylase Inhibitors: Confirmed Efficacy with Uncertain Safety”

Subject Area:
Nephrology
Hiroyasu Yamamoto, Kiyoshi Nobori, Yoshimi Matsuda, Yasuhiro Hayashi, Takanori Hayasaki, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2022) 52 (12): 977–978.
https://doi.org/10.1159/000520156
Published Online: 02 November 2021
View article titled, Letter in Response to “HIF-Prolyl Hydroxylase Inhibitors: Confirmed Efficacy with Uncertain Safety”
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Journal Articles

Factors Affecting Doses of Roxadustat Versus Darbepoetin Alfa for Anemia in Nondialysis Patients

Subject Area:
Nephrology
Tadao Akizawa, Keiko Tanaka-Amino, Tetsuro Otsuka, Yusuke Yamaguchi
Journal: American Journal of Nephrology
Am J Nephrol (2021) 52 (9): 702–713.
https://doi.org/10.1159/000519043
Published Online: 08 October 2021
View article titled, Factors Affecting Doses of Roxadustat Versus Darbepoetin Alfa for Anemia in Nondialysis Patients
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Journal Articles

Efficacy and Safety of Molidustat for Anemia in ESA-Naive Nondialysis Patients: A Randomized, Phase 3 Trial

Subject Area:
Nephrology
Hiroyasu Yamamoto, Kiyoshi Nobori, Yoshimi Matsuda, Yasuhiro Hayashi, Takanori Hayasaki, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2021) 52 (10-11): 871–883.
https://doi.org/10.1159/000518071
Published Online: 16 September 2021
View article titled, Efficacy and Safety of Molidustat for Anemia in ESA-Naive Nondialysis Patients: A Randomized, Phase 3 Trial
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Journal Articles

Molidustat for Renal Anemia in Nondialysis Patients Previously Treated with Erythropoiesis-Stimulating Agents: A Randomized, Open-Label, Phase 3 Study

Subject Area:
Nephrology
Hiroyasu Yamamoto, Kiyoshi Nobori, Yoshimi Matsuda, Yasuhiro Hayashi, Takanori Hayasaki, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2021) 52 (10-11): 884–893.
https://doi.org/10.1159/000518072
Published Online: 16 September 2021
View article titled, Molidustat for Renal Anemia in Nondialysis Patients Previously Treated with Erythropoiesis-Stimulating Agents: A Randomized, Open-Label, Phase 3 Study
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Journal Articles

Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia

Subject Area:
Nephrology
Takashi Shigematsu, Yotaro Une, Kazuaki Ikejiri, Hironori Kanda, Masafumi Fukagawa, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2021) 52 (6): 496–506.
https://doi.org/10.1159/000516156
Published Online: 07 June 2021
View article titled, Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia
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Journal Articles

Daprodustat Compared with Epoetin Beta Pegol for Anemia in Japanese Patients Not on Dialysis: A 52-Week Randomized Open-Label Phase 3 Trial

Subject Area:
Nephrology
Masaomi Nangaku, Takayuki Hamano, Tadao Akizawa, Yoshiharu Tsubakihara, Reiko Nagai, Nobuhiko Okuda, Kyo Kurata, Takashi Nagakubo, Nigel P. Jones, Yukihiro Endo, Alexander R. Cobitz
Journal: American Journal of Nephrology
Am J Nephrol (2021) 52 (1): 26–35.
https://doi.org/10.1159/000513103
Published Online: 09 February 2021
View article titled, Daprodustat Compared with Epoetin Beta Pegol for Anemia in Japanese Patients Not on Dialysis: A 52-Week Randomized Open-Label Phase 3 Trial
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Journal Articles

Intra-Dialytic Hemoglobin Changes and Cardiovascular Events: A Cohort Study on Dialysis Outcomes and Practice Patterns in Japan

Subject Area:
Nephrology
Takashi Hara, Miho Kimachi, Tatsuyoshi Ikenoue, Tadao Akizawa, Shunichi Fukuhara, Yosuke Yamamoto
Journal: American Journal of Nephrology
Am J Nephrol (2019) 50 (4): 272–280.
https://doi.org/10.1159/000502633
Published Online: 05 September 2019
View article titled, Intra-Dialytic Hemoglobin Changes and Cardiovascular Events: A Cohort Study on Dialysis Outcomes and Practice Patterns in Japan
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Journal Articles

Long-Term Efficacy and Safety of Molidustat for Anemia in Chronic Kidney Disease: DIALOGUE Extension Studies

Subject Area:
Nephrology
Tadao Akizawa, Iain C. Macdougall, Jeffrey S. Berns, Thomas Bernhardt, Gerald Staedtler, Megumi Taguchi, Kazuma Iekushi, Thilo Krueger
Journal: American Journal of Nephrology
Am J Nephrol (2019) 49 (4): 271–280.
https://doi.org/10.1159/000499111
Published Online: 08 March 2019
View article titled, Long-Term Efficacy and Safety of Molidustat for Anemia in Chronic Kidney Disease: DIALOGUE Extension Studies
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Journal Articles

A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial

Subject Area:
Nephrology
Tadao Akizawa, Masaomi Nangaku, Takuhiro Yamaguchi, Masanobu Arai, Ryosuke Koretomo, Atsushi Matsui, Hideki Hirakata
Journal: American Journal of Nephrology
Am J Nephrol (2019) 49 (2): 165–174.
https://doi.org/10.1159/000496929
Published Online: 30 January 2019
View article titled, A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial
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Journal Articles

Body Mass Index Change and Hospitalization Risk in Elderly Hemodialysis Patients: Results from Japanese Dialysis Outcomes and Practice Patterns Study

Subject Area:
Nephrology
Keiichi Sumida, Shungo Yamamoto, Tadao Akizawa, Shunichi Fukuhara, Shingo Fukuma
Journal: American Journal of Nephrology
Am J Nephrol (2018) 47 (1): 48–56.
https://doi.org/10.1159/000486559
Published Online: 24 January 2018
View article titled, Body Mass Index Change and Hospitalization Risk in Elderly Hemodialysis Patients: Results from Japanese Dialysis Outcomes and Practice Patterns Study
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Journal Articles

Interactive Effectiveness of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers or Their Combination on Survival of Hemodialysis Patients

Subject Area:
Nephrology
Ryo Kido, Tadao Akizawa, Masafumi Fukagawa, Yoshihiro Onishi, Takuhiro Yamaguchi, Shunichi Fukuhara
Journal: American Journal of Nephrology
Am J Nephrol (2018) 46 (6): 439–447.
https://doi.org/10.1159/000482013
Published Online: 21 November 2017
View article titled, Interactive Effectiveness of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers or Their Combination on Survival of Hemodialysis Patients
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Journal Articles

Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects

Subject Area:
Nephrology
Tadao Akizawa, Yoshiharu Tsubakihara, Masaomi Nangaku, Yukihiro Endo, Hiromu Nakajima, Tomoko Kohno, Yukiko Imai, Natsumi Kawase, Katsutoshi Hara, John Lepore, Alexander Cobitz
Journal: American Journal of Nephrology
Am J Nephrol (2017) 45 (2): 127–135.
https://doi.org/10.1159/000454818
Published Online: 16 December 2016
View article titled, Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects
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Journal Articles

Rationale and Trial Design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: The Occurrence of Renal Events (BEACON)

Subject Area:
Topic Article Package: Diabetes , Nephrology
Dick de Zeeuw, Tadao Akizawa, Rajiv Agarwal, Paul Audhya, George L. Bakris, Melanie Chin, Melissa Krauth, Hiddo J. Lambers Heerspink, Colin J. Meyer, John J. McMurray, Hans-Henrik Parving, Pablo E. Pergola, Giuseppe Remuzzi, Robert D. Toto, Nosratola D. Vaziri, Christoph Wanner, David G. Warnock, Janet Wittes, Glenn M. Chertow
Journal: American Journal of Nephrology
Am J Nephrol (2013) 37 (3): 212–222.
https://doi.org/10.1159/000346948
Published Online: 28 February 2013
View article titled, Rationale and Trial Design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: The Occurrence of Renal Events (BEACON)
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Journal Articles

Mineral Metabolism Management in Hemodialysis Patients with Secondary Hyperparathyroidism in Japan: Baseline Data from the MBD-5D

Subject Area:
Nephrology
Masafumi Fukagawa, Hirotaka Komaba, Yoshihiro Onishi, Shunichi Fukuhara, Tadao Akizawa, Kiyoshi Kurokawa, for the MBD-5D Study Group
Journal: American Journal of Nephrology
Am J Nephrol (2011) 33 (5): 427–437.
https://doi.org/10.1159/000327654
Published Online: 21 April 2011
View article titled, Mineral Metabolism Management in Hemodialysis Patients with Secondary Hyperparathyroidism in Japan: Baseline Data from the MBD-5D
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Journal Articles

Effects of Calcimimetic Combined with an Angiotensin-Converting Enzyme Inhibitor on Uremic Cardiomyopathy Progression

Subject Area:
Nephrology
Masahide Mizobuchi, Hiroaki Ogata, Nozomu Hosaka, Chiaki Kumata, Ai Nakazawa, Fumiko Kondo, Fumihiko Koiwa, Eriko Kinugasa, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2011) 34 (3): 256–267.
https://doi.org/10.1159/000330188
Published Online: 11 April 2011
View article titled, Effects of Calcimimetic Combined with an Angiotensin-Converting Enzyme Inhibitor on Uremic Cardiomyopathy Progression
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Journal Articles

Involvement of Alpha-Klotho and Fibroblast Growth Factor Receptor in the Development of Secondary Hyperparathyroidism

Subject Area:
Nephrology
Chiaki Kumata, Masahide Mizobuchi, Hiroaki Ogata, Fumihiko Koiwa, Ai Nakazawa, Fumiko Kondo, Yoshiyuki Kadokura, Eriko Kinugasa, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2010) 31 (3): 230–238.
https://doi.org/10.1159/000274483
Published Online: 06 January 2010
View article titled, Involvement of Alpha-Klotho and Fibroblast Growth Factor Receptor in the Development of Secondary Hyperparathyroidism
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Journal Articles

Long-Term Cinacalcet HCl Treatment Improved Bone Metabolism in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism

Subject Area:
Nephrology
Takashi Shigematsu, Tadao Akizawa, Eiji Uchida, Yusuke Tsukamoto, Manabu Iwasaki, Shouzo Koshikawa
Journal: American Journal of Nephrology
Am J Nephrol (2009) 29 (3): 230–236.
https://doi.org/10.1159/000156717
Published Online: 17 September 2008
View article titled, Long-Term Cinacalcet HCl Treatment Improved Bone Metabolism in Japanese Hemodialysis Patients with Secondary Hyperparathyroidism
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Journal Articles

Direct Injection of Calcitriol or Its Analog Improves Abnormal Gene Expression in the Hyperplastic Parathyroid Gland in Uremia

Subject Area:
Nephrology
Kazuhiro Shiizaki, Masafumi Fukagawa, Qunsheng Yuan, Ikuji Hatamura, Tomoko Nii-Kono, Fumie Saji, Takashi Shigematsu, Tadao Akizawa
Journal: American Journal of Nephrology
Am J Nephrol (2007) 28 (1): 59–66.
https://doi.org/10.1159/000109240
Published Online: 28 September 2007
View article titled, Direct Injection of Calcitriol or Its Analog Improves Abnormal Gene Expression in the Hyperplastic Parathyroid Gland in Uremia
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