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Online First / Early View
Online first articles are accepted and edited, peer reviewed articles that are not yet assigned to volumes/issues, but are citable using DOI.
Online First
Research Articles May 23 2025
Nephrology Provider Perceptions about Recommending Influenza and COVID-19 Vaccines: A Nationwide Survey
Guangchen Zou; Lawrence Appel; Deidra C. Crews; David Dowdy; Kunihiro Matsushita; Kristin A. Riekert; Bernard G. Jaar; Junichi Ishigami
Am J Nephrol (2025) https://doi.org/10.1159/000544935
Research Articles May 19 2025
Additive Obinutuzumab Achieves High Remission Rates in Rituximab-Refractory Membranous Nephropathy
Huixian Li; Li Jin; Xinfang Xie; Jiping Sun; Dan Niu; Jie Feng; Guiqing Xu; Xiaotian Zhang; Abdulrahman Majeed S. Khalaf; Wanhong Lu
Am J Nephrol (2025) https://doi.org/10.1159/000545995
Research Articles May 19 2025
Utilizing Deep Learning to Identify Electron-Dense Deposits in Renal Biopsy Electron Microscopy Images
Shuangshuang Zhu; Bei Luo; Sendong Lai; Shuling Yue; Guang Yang; Zhen Song; Xiaomeng Xu; Yangyang Gui; Anlan Chen; Hongmei Yu; Yanqiu Liu; Hongyu Liu; Chao Yang; Lei Zheng
Am J Nephrol (2025) https://doi.org/10.1159/000546131
Research Articles May 19 2025
Time in Target Range of Systolic Blood Pressure and Cardiovascular Disease in Patients with Chronic Kidney Disease: A Korean Nationwide Cohort Study
Am J Nephrol (2025) https://doi.org/10.1159/000546380
Research Articles May 10 2025
Intradialytic Cognitive and Aerobic Exercise Training to Preserve Cognitive Function: IMPCT, a Multi-Dialysis Center 2 × 2 Factorial Block-Randomized Controlled Trial
Nidhi Ghildayal; Yi Liu; Jingyao Hong; Yiting Li; Xiaomeng Chen; Marlís González Fernández; Michelle C. Carlson; Derek M. Fine; Lawrence J. Appel; Marie Diener-West; David M. Charytan; Aarti Mathur; Dorry L. Segev; Mara McAdams-DeMarco
Am J Nephrol (2025) https://doi.org/10.1159/000546296
Research Articles May 6 2025
Peridialytic Erythropoietin versus Roxadustat in Hemodialysis-Dependent Chronic Kidney Disease Patients
Am J Nephrol (2025) https://doi.org/10.1159/000546158
Research Articles May 5 2025
Association between Rheumatoid Arthritis and the Incidence of IgA Nephropathy
Tatsuhiko Azegami; Hidehiro Kaneko; Akira Okada; Yuta Suzuki; Katsuhito Fujiu; Takashin Nakayama; Norifumi Takeda; Hiroyuki Morita; Norihiko Takeda; Akira Fukui; Takashi Yokoo; Yuko Kaneko; Hideo Yasunaga; Masaomi Nangaku; Kaori Hayashi
Am J Nephrol (2025) https://doi.org/10.1159/000546196
Research Articles May 5 2025
Association between Parathyroid Hormone Concentration and Incident Atrial Fibrillation in Older Persons with Kidney Failure Initiating Dialysis
Pascale Khairallah; Sai Liu; Maria E. Montez-Rath; Kevin F. Erickson; Tara I. Chang; Wolfgang C. Winkelmayer
Am J Nephrol (2025) https://doi.org/10.1159/000546266
Research Articles May 3 2025
Sociodemographic Barriers to Starting the Kidney Transplantation Evaluation Process and Waitlisting in the Ohio River Valley
Catherine E. Kelty; Jade Buford; Kelsey M. Drewry; Oluwafisayo Adebiyi; Asif Sharfuddin; Jonathan A. Fridell; Syed Jawad Sher; Anne M. Huml; Adam S. Wilk; Stephen O. Pastan; Sharon M. Moe; Rachel E. Patzer
Am J Nephrol (2025) https://doi.org/10.1159/000546108
Research Articles May 3 2025
Urinary Cytokeratin 20 Predicts Severe Acute Kidney Injury and Major Adverse Kidney Events in Adults Undergoing Cardiac Surgery
Rui Ma; Han Ouyang; Chunbo Chen; Xin Xu; Jianwei Tian; Ruhe Zhong; Yan Zha; Siyuan Teng; Guisen Li; Huafeng Liu; Xiaobing Yang; Fan Fan Hou
Am J Nephrol (2025) https://doi.org/10.1159/000546159
Brief Reports April 29 2025
GLPG2737, a CFTR Inhibitor, Prevents Cyst Growth in Preclinical Models of Autosomal Dominant Polycystic Kidney Disease
Vincent Dumont; Sandrine Meurisse; Katleen Verdonck; Valérie Salgues; Tiffany Robert; Florence Anquetil; Carole Delachaume; Roland Blanqué; Daisy Liekens; Yan Huang; Jinghua Hu; Peter C. Harris; Jessica Nakhlé; Katja Conrath; Nick Vandeghinste; Thierry Christophe; Daniel Comas
Am J Nephrol (2025) https://doi.org/10.1159/000545614
Research Articles April 28 2025
Association between Systemic Inflammation and Worsening Renal Function in Cardiovascular-Kidney-Metabolic Syndrome
Sunying Wang; Jilang Zeng; Yan Chen; Fuqing Sun; Hanghao Ma; Liwei Zhang; Zhijie Lin; Changxi Wang; Yuwei Wang; Qingyong Yang; Manqing Luo; Kaiyang Lin; Yansong Guo
Am J Nephrol (2025) https://doi.org/10.1159/000546130
Review Articles April 23 2025
Paraneoplastic Glomerulopathies: Mechanistic and Pathogenic Insights
Am J Nephrol (2025) https://doi.org/10.1159/000546050
Research Articles April 18 2025
Longitudinal Changes in Peritoneal Transport and Their Impact on Dialysis Outcomes: A Machine Learning Approach Integrating Clinical and Biomarker Data
Chia-Chun Lee; Jo-Yen Chao; Kuan-Hung Liu; Wei-Ren Lin; Te-Hui Kuo; An-Bang Wu; Ming-Cheng Wang; Sheng-Hsiang Lin; Chin-Chung Tseng
Am J Nephrol (2025) https://doi.org/10.1159/000545943
Research Articles April 16 2025
Neutrophil Percentage-to-Albumin Ratio as a Predictor of Acute Kidney Injury in Cirrhotic Patients: A Novel Approach Utilizing Artificial Intelligence
Nasser Mousa; Sherif Elbaz; Alaa Elmetwalli; Mostafa Abdelsalam; Eman Abdelkader; Mohamed Wahba; Mohammed Abdelaziz; Ola El-Emam; Niveen El-Wakeel; Mohamed Shaheen; Badawy Abo-Bakr; Muhammad Diasty; Naglaa Abbas; Mohamed Selim; Marwa Mansour
Am J Nephrol (2025) https://doi.org/10.1159/000545639
Research Articles April 15 2025
Glomerular Basement Membrane Thickness Estimation and Stratification via Active Semi-Supervised Learning Model
Nico Curti; Gianluca Carlini; Sabrina Valente; Enrico Giampieri; Alessandra Merlotti; Daniel Remondini; Gaetano La Manna; Gastone Castellani; Gianandrea Pasquinelli
Am J Nephrol (2025) https://doi.org/10.1159/000542658
Research Articles April 10 2025
Renal Ischemia Induces Endoplasmic Reticulum Stress and Impairs the Reparative Potency of Scattered Tubular-Like Cells
Sara Kazeminia; Barnit Kaur; Kumar Shivam; Xiang-Yang Zhu; Hui Tang; Kyra L. Jordan; Shivam Bajpai; Ailing Xue; Alejandro R. Chade; Maria V. Irazabal; Lilach O. Lerman; Alfonso Eirin
Am J Nephrol (2025) https://doi.org/10.1159/000545795
Research Articles March 29 2025
Relationship between Cumulative Exposure and Time Course of Plasma Aldosterone Concentrations and Chronic Kidney Disease in Hypertensive Patients: A Real-World Cohort Study
Shuaiwei Song; Xintian Cai; Di Shen; Junli Hu; Qing Zhu; Huimin Ma; Yingying Zhang; Rui Ma; Pan Zhou; Zhiqiang Zhang; Wenbo Yang; Wen Jiang; Jing Hong; Delian Zhang; Nanfang Li
Am J Nephrol (2025) https://doi.org/10.1159/000545451
Research Articles March 19 2025
The Role of Neutrophils in Venous Thrombosis in Primary Membranous Nephropathy
Am J Nephrol (2025) https://doi.org/10.1159/000545296
Research Articles March 17 2025
Adverse Prognosis in Membranous Nephropathy with Phospholipase A2 Receptor 1 Epitope Spreading: A Prospective Study
Am J Nephrol (2025) https://doi.org/10.1159/000545133
Research Articles March 14 2025
Pharmacokinetic Properties of Dapagliflozin in Patients with Stage 4 Chronic Kidney Disease
Dan Li; Di Xie; Ancheng Gu; Yaya Yang; Zhijian Guo; Xianglan Huang; Jun Li; Jun Wang; Lei Zhang; Bianxiang Hu; Xiaobing Yang; Yan Huang; Wanwen Cao; Yerong Wei; Jiali He; Zhongyuan Xu; Min Liang
Am J Nephrol (2025) https://doi.org/10.1159/000544936
Research Articles March 13 2025
Associations between Multimorbidity and the Risks of Cardiovascular Disease Events and All-Cause Mortality in Patients with Chronic Kidney Disease
Kazuhiro Okamura; Shigeru Tanaka; Hiromasa Kitamura; Tatsuya Suenaga; Kazuhiko Tsuruya; Takanari Kitazono; Toshiaki Nakano; for the Fukuoka Kidney Disease Registry (FKR) Study Collaboration Group
Am J Nephrol (2025) https://doi.org/10.1159/000544722
Research Articles March 13 2025
Exosomal Specificity of MiR-15a-5p as Marker of Activity, Renal Damage, and Disease Flares in Systemic Lupus Erythematosus
Ana Flores-Chova; Olga Martinez-Arroyo; Ana Puertes; Sara Vela-Bernal; Jose Luis Gorriz; Miguel A. Solis-Salguero; Liria Terradez; Ana Ortega; Maria J. Forner; Raquel Cortes
Am J Nephrol (2025) https://doi.org/10.1159/000544854
Research Articles March 5 2025
Edema and Outcome in Patients with Nephrotic-Range Albuminuria and Hypoalbuminemia: A Danish Multicenter Cohort Study
Sarah Kelddal; Bawer Jalal Tofig; Anne-Mette Hvas; Erik Lerkevang Grove; Christian Fynbo Christiansen; Henrik Birn
Am J Nephrol (2025) https://doi.org/10.1159/000544759
Research Articles March 4 2025
IgA Nephropathy and the Risk of Primary Infections: A Swedish Population-Based Cohort Study
Am J Nephrol (2025) https://doi.org/10.1159/000544753
Systematic Review March 3 2025
Clinical Outcomes of Patients undergoing Hemodialysis with Cool versus Standard Dialysate: A Systematic Review and Meta-Analysis
Subhash Chander; Rabia Latif; Ahmad Bin Aamir; Fnu Sorath; Abhi Chand Lohana; Mohammed Yaqub Nadeem; Om Parkash
Am J Nephrol (2025) https://doi.org/10.1159/000544924
Research Articles February 26 2025
Impact of Renin-Angiotensin-Aldosterone System Inhibition on Advanced Chronic Kidney Disease Progression: A Retrospective Observational Study
Am J Nephrol (2025) https://doi.org/10.1159/000543487
Research Articles February 26 2025
Sex Disparity and the Uptake of Home Dialysis following Kidney Transplant Failure
Wai Lim; Ryan Gately; Armando Teixeira-Pinto; Pedro Lopez; Dharshana Sabanayagam; William R. Mulley; Helen Pilmore; Doris Chan; Esther Ooi; Charmaine Lok; Germaine Wong
Am J Nephrol (2025) https://doi.org/10.1159/000543788
Research Articles February 25 2025
Five-Year Time Profiles of Clearances of Different Uremic Solutes in Incident Peritoneal Dialysis Patients
Ji Ji; Min Lu; Shulan Guo; Bo Xiang; Weiwei Wu; Yang Li; Xiaoyan Jiao; Jun Ji; Xiaoqiang Ding; Xiaofang Yu
Am J Nephrol (2025) https://doi.org/10.1159/000543622
Review Articles February 25 2025
Electrolytes Abnormalities in Cancer Patients
Am J Nephrol (2025) https://doi.org/10.1159/000544877
Research Articles February 21 2025
Adjunctive Active Vitamin D Decreases Kidney Function during Treatment of Secondary Hyperparathyroidism with Extended-Release Calcifediol in Non-Dialysis Chronic Kidney Disease in a Randomized Trial
Akhtar Ashfaq; John Choe; Stephen A. Strugnell; Nilay Patel; Stuart M. Sprague; Keith C. Norris; Edgar Lerma; P. Martin Petkovich; Charles W. Bishop
Am J Nephrol (2025) https://doi.org/10.1159/000544086
Research Articles February 20 2025
Fibroblast Growth Factor 23, Endogenous Erythropoietin, Erythropoiesis-Stimulating Agents, and Erythropoietin Resistance in Hemodialysis Patients
Naoto Hamano; Hirotaka Komaba; Hisae Tanaka; Hiroo Takahashi; Yuichiro Takahashi; Toru Hyodo; Miho Hida; Takao Suga; Takehiko Wada; Takatoshi Kakuta; Masafumi Fukagawa
Am J Nephrol (2025) https://doi.org/10.1159/000543506
Brief Reports February 20 2025
Supplement-Induced Acute Kidney Injury Reproduced in Kidney Organoids
Am J Nephrol (2025) https://doi.org/10.1159/000544795
Review Articles February 20 2025
Immunotherapy and Cellular Therapies for Cancers in Kidney Transplant Patients
Am J Nephrol (2025) https://doi.org/10.1159/000544826
Research Articles February 12 2025
DOT1L Regulates Cellular Senescence during the Progression from Acute Kidney Injury to Chronic Kidney Disease via the microRNA-222-5p/WNT9B Signaling Pathway
Congcong Yao; Wei Wei; Guoyu Wu; Yan Zhang; Keke Sun; Zhiyuan Liu; Yushanjiang Abudureheman; Heng Wu; Qi Lv; Ayinuer Paredong; Songtao Shou; Heng Jin
Am J Nephrol (2025) https://doi.org/10.1159/000544694
Research Articles February 11 2025
The Value of Diffusion Kurtosis Imaging to Assess Liver and Kidney Recovery after Mesenchymal Stem Cell Intervention in CCl4-Induced Cirrhotic Rats
Jiaming Qin; Shuangshuang Xie; Yongquan Yu; Cheng Zhang; Yumeng Zhao; Dan Tong; Zhandong Hu; Jinxia Zhu; Wen Shen
Am J Nephrol (2025) https://doi.org/10.1159/000544056
Research Articles February 3 2025
Early-Onset Peritonitis and Outcomes of Peritoneal Dialysis: A Cohort Study with Data from the RDPLF
Lucas Poulain; Clémence Bechade; Antoine Lanot; Maxence Ficheux; Sonia Guillouet; Thierry Lobbedez; Annabel Boyer
Am J Nephrol (2025) https://doi.org/10.1159/000542835
Brief Reports February 3 2025
Gender Differences in Kidney Failure Incidence in Australia: A Registry Study
Am J Nephrol (2025) https://doi.org/10.1159/000543663
Research Articles January 27 2025
The Association of Niacin Use with Kidney Outcomes and Mortality
Rina Takahashi; Thuy-Anh Bui; Ibrahim Elali; Diana Tran; Keiichi Sumida; Fridtjof Thomas; Ramanath Dukkipati; Anuja Shah; Connie M. Rhee; Csaba P. Kovesdy; Kamyar Kalantar-Zadeh
Am J Nephrol (2025) https://doi.org/10.1159/000543098
Research Articles January 27 2025
Relationship between Podocyte Injury and Renal Outcomes in Patients with Acute Kidney Injury: A Report from a Retrospective Study in China
Shun Wu; Mengling Guo; Yudan Wang; Yilun Zhou; Liyuan Zhang; Yun Zhou; Yuanyuan Xing; Dong Sun; Xueqing Hu; Zhenmin Ruan; John Cijiang He; Hongqi Ren
Am J Nephrol (2025) https://doi.org/10.1159/000543789
Research Articles January 24 2025
Association between Serum Zinc Levels and Trabecular Bone Scores among Patients Undergoing Chronic Hemodialysis
Am J Nephrol (2025) https://doi.org/10.1159/000543756
Research Articles January 22 2025
Significant Dry Weight Reduction after Transition from Peritoneal Dialysis to Hemodialysis
Am J Nephrol (2025) https://doi.org/10.1159/000543598
Review Articles January 7 2025
Immune Checkpoint Inhibitor-Related Acute Kidney Injury: Management and Challenges
Am J Nephrol (2025) https://doi.org/10.1159/000543323
Commentaries October 24 2024
Does Correction of Secondary Hyperparathyroidism with Extended-Release Calcifediol Provide Renoprotection?
Am J Nephrol (2024) https://doi.org/10.1159/000541614
Research Articles August 27 2024
Sustained Reduction of Elevated Intact Parathyroid Hormone Concentrations with Extended-Release Calcifediol Slows Chronic Kidney Disease Progression in Secondary Hyperparathyroidism Patients
Charles W. Bishop; Akhtar Ashfaq; Stephen A. Strugnell; John Choe; Nilay Patel; Keith C. Norris; Stuart M. Sprague
Am J Nephrol (2024) https://doi.org/10.1159/000541138
Review Articles June 12 2024
Kidney Amyloidosis: Updates on Pathogenesis and Therapeutic Frontiers
Am J Nephrol (2024) https://doi.org/10.1159/000539596
Review Articles March 18 2024
Onco-Hypertension in Patients with Kidney Disease
Am J Nephrol (2024) https://doi.org/10.1159/000538375
Early View
Review Articles June 18 2025
SGLT-2 inhibitors: a deeper dive into their renal protective properties beyond glycemic control and proteinuria reduction
Am J Nephrol (2025) https://doi.org/10.1159/000546079
Research Articles June 17 2025
Assessing Rural Veterans’ Experiences with a Tele-Nephrology Program in the Veterans Health Administration (VHA)
Kristin M. Mattocks; Lorrie Walker; Aimee Kroll-Desrosiers; Susan Crowley; David T. Moore; Ramon Bonegio
Am J Nephrol (2025) https://doi.org/10.1159/000546917
Research Articles June 17 2025
Using Machine learning to predict medication therapy problems among patients with chronic kidney disease
Alaa A. Alghwiri; Melanie R. Weltman; Linda-Marie U. Lavenburg; Zhuoheng Han; Thomas D. Nolin; Yi-Fan Chen; Jonathan G. Yabes; Manisha Jhamb
Am J Nephrol (2025) https://doi.org/10.1159/000546540
Review Articles June 13 2025
The role of cell–cell communication in renal damage and the therapeutic targeting of diabetic kidney disease
Linxiao Lv; Wen Zheng; Mingyang Hu; Gladys Lai Ying Cheing; Zhangsuo Liu; Sijie Zhou; Alex Kwok Kuen Cheung
Am J Nephrol (2025) https://doi.org/10.1159/000546739
Letters June 11 2025
Are Your Kidneys Ok? Detect early to protect kidney health Running title: Are Your Kidneys Ok?
Joseph A. Vassalotti; Anna Francis; Augusto Cesar Soares dos Santos Jr; Ricardo Correa-Rotter; Dina Abdellatif; Li-Li Hsiao; Stefanos Roumeliotis; Agnes Haris; Latha A. Kumaraswami; Siu-Fai Lui; Alessandro Balducci; Vassilios Liakopoulos; On behalf of World Kidney Day Joint Steering Committee
Am J Nephrol (2025) https://doi.org/10.1159/000546586
Methods Article June 9 2025
Inhibition of Calcium Release-Activated Calcium (CRAC) channels to Treat Acute Kidney Injury: Design and Rationale of the KOURAGE study
Lakhmir S. Chawla; Patrick T. Murray; Stuart L. Goldstein; Andrew Cunningham; Sudarshan Hebbar; Richard G. Wunderink; Glenn M. Chertow
Am J Nephrol (2025) https://doi.org/10.1159/000546863
Research Articles June 4 2025
Extended-Release Calcifediol Normalized 1,25-Dihydroxyvitamin D and Prevented Progression of Secondary Hyperparathyroidism in Hemodialysis Patients in a Randomized Clinical Trial
Charles W. Bishop; Akhtar Ashfaq; John Choe; Stephen A. Strugnell; Laura L. Johnson; Keith C. Norris; Stuart M. Sprague
Am J Nephrol (2025) https://doi.org/10.1159/000546615
Brief Reports May 28 2025
Eligibility of Living Kidney Donors with Kidney Stone Disease
Tyler R. Compher; Sambhavi Krishnamoorthy; Kyle D. Wood; Michael J. Hanaway; Shikha Mehta; Vineeta Kumar; Dean G. Assimos; Anna L. Zisman; Joseph J. Crivelli
Am J Nephrol (2025) https://doi.org/10.1159/000546373