Background: The socioeconomic status of a person has an impact on his or her access to kidney transplantation as has been reported in western countries. This study examined the association between income level and kidney transplantation among chronic kidney disease patients undergoing dialysis in South Korea. Methods: We analyzed data from 1,792 chronic kidney disease patients undergoing dialysis and listed in the Korean National Health Insurance Claim Database (2003-2013). The likelihood of receiving the first kidney transplant over time was analyzed using competing risk proportional hazard models on time from initiating dialysis to receiving a transplant. Results: Of 1,792 patients on dialysis, only 184 patients (10.3%) received kidney transplants. Patients with medical aid had the lowest kidney transplantation rate (hazard ratio 0.29, 95% CI 0.16-0.51). A lower income level was significantly associated with a low kidney transplantation rate, after adjusting for covariates, compared to patients in the high-income level group. Conclusions: Our findings indicate that in South Korea, the total number of kidney transplants is remarkably low and there exists income disparity with regard to access to kidney transplantation. Thus, we suggest that plans be implemented to encourage organ donation and increase organ transplant accessibility for all patients irrespective of their socioeconomic status.

1.
Meguid El Nahas A, Bello AK: Chronic kidney disease: the global challenge. Lancet 2005;365:331-340.
2.
Jin DC, Ha IS, Kim NH, et al: Brief report: renal replacement therapy in Korea, 2010. Kidney Res Clin Pract 2012;31:62-71.
3.
Collins AJ, Foley RN, Chavers B, et al: United States renal data system 2011 annual data report: atlas of chronic kidney disease & end-stage renal disease in the United States. Am J Kidney Dis 2012;59(1 suppl 1):A7, e1-e420.
4.
Young CJ, Gaston RS: Renal transplantation in black Americans. N Engl J Med 2000;343:1545-1552.
5.
Sánchez-Escuredo A, Alsina A, Diekmann F, et al: Economic analysis of the treatment of end-stage renal disease treatment: living-donor kidney transplantation versus hemodialysis. Transplant Proc 2015;47:30-33.
6.
Kim SI, Kim YS, Kim MS, et al: A renal transplantation and hemodialysis cost-utility analysis in patients with end-stage renal disease. J Korean Soc Transplant 2010;24:173-181.
7.
Howard K, Salkeld G, White S, et al: The cost-effectiveness of increasing kidney transplantation and home-based dialysis. Nephrology (Carlton) 2009;14:123-132.
8.
Park K, Moon JI, Kim SI, Kim YS: Exchange-donor program in kidney transplantation. Transplant Proc 1999;67:336-338.
9.
Park K, Lee JH, Huh KH, Kim SI, Kim YS: Exchange living-donor kidney transplantation: diminution of donor organ shortage. Transplant Proc 2004;36:2949-2951.
10.
Axelrod DA, Dzebisashvili N, Schnitzler MA, et al: The interplay of socioeconomic status, distance to center, and interdonor service area travel on kidney transplant access and outcomes. Clin J Am Soc Nephrol 2010;5:2276-2288.
11.
Ayanian JZ, Cleary PD, Weissman JS, Epstein AM: The effect of patients' preferences on racial differences in access to renal transplantation. N Engl J Med 1999;341:1661-1669.
12.
Crews DC, Charles RF, Evans MK, Zonderman AB, Powe NR: Poverty, race, and CKD in a racially and socioeconomically diverse urban population. Am J Kidney Dis 2010;55:992-1000.
13.
Hall Y, O'Hare AM, Young BA, Boyko EJ, Chertow GM: Neighborhood poverty and kidney transplantation among US Asians and Pacific Islanders with end-stage renal disease. Am J Transplant 2008;8:2402-2409.
14.
Goldfarb-Rumyantzev AS, Koford JK, Baird BC, et al: Role of socioeconomic status in kidney transplant outcome. Clin J Am Soc Nephrol 2006;1:313-322.
15.
Grace BS, Clayton PA, Cass A, McDonald SP: Transplantation rates for living- but not deceased-donor kidneys vary with socioeconomic status in Australia. Kidney Int 2013;83:138-145.
16.
Cass A, Cunningham J, Arnold PC, Snelling P, Wang Z, Hoy W: Delayed referral to a nephrologist: outcomes among patients who survive at least one year on dialysis. Med J Aust 2002;177:135-138.
17.
Patzer RE, Amaral S, Wasse H, Volkova N, Kleinbaum D, McClellan WM: Neighborhood poverty and racial disparities in kidney transplant waitlisting. J Am Soc Nephrol 2009;20:1333-1340.
18.
Jindal RM, Ryan JJ, Sajjad I, Murthy MH, Baines LS: Kidney transplantation and gender disparity. Am J Nephrol 2004;25:474-483.
19.
Ashby VB, Kalbfleisch JD, Wolfe RA, Lin MJ, Port FK, Leichtman AB: Geographic variability in access to primary kidney transplantation in the United States, 1996-2005. Am J Transplant 2007;7(5 pt 2):1412-1423.
20.
Kjellstrand CM: Age, sex, and race inequality in renal transplantation. Arch Intern Med 1988;148:1305-1309.
21.
Imai E, Matsuo S: Chronic kidney disease in Asia. Lancet 2008;371:2147-2148.
22.
Tong A, Chapman JR, Kee T, et al: Perspectives of transplant professionals on the values, ethics, and challenges of living kidney donor evaluation in Asia. Transplantation 2015;99:1386-1395.
23.
Kim JR, Elliott D, Hyde C: The influence of sociocultural factors on organ donation and transplantation in Korea: findings from key informant interviews. J Transcult Nurs 2004;15:147-154.
24.
Kim H, Kim KH, Park K, et al: A population-based approach indicates an overall higher patient mortality with peritoneal dialysis compared to hemodialysis in Korea. Kidney Int 2014;86:991-1000.
25.
Fine JP, Gray RJ: A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 1999;94:496-509.
26.
Rhee CM, Lertdumrongluk P, Streja E, et al: Impact of age, race and ethnicity on dialysis patient survival and kidney transplantation disparities. Am J Nephrol 2014;39:183-194.
27.
Weng FL, Joffe MM, Feldman HI, Mange KC: Rates of completion of the medical evaluation for renal transplantation. Am J Kidney Dis 2005;46:734-745.
28.
Patzer RE, Amaral S, Klein M, et al: Racial disparities in pediatric access to kidney transplantation: does socioeconomic status play a role? Am J Transplant 2012;12:369-378.
29.
Keith D, Ashby VB, Port FK, Leichtman AB: Insurance type and minority status associated with large disparities in prelisting dialysis among candidates for kidney transplantation. Clin J Am Soc Nephrol 2008;3:463-470.
30.
Johansen KL, Zhang R, Huang Y, Patzer RE, Kutner NG: Association of race and insurance type with delayed assessment for kidney transplantation among patients initiating dialysis in the United States. Clin J Am Soc Nephrol 2012;7:1490-1497.
31.
OECD: Treatment of Renal Failure (Diablysis and Kidney Tranplant), in Health at a Glance 2011: OECD Indicators, OECD Publishing. (accessed November 2011).
32.
Alexander GC, Sehgal AR: Barriers to cadaveric renal transplantation among blacks, women, and the poor. JAMA 1998;280:1148-1152.
33.
Held PJ, Pauly MV, Bovbjerg RR, Newmann J, Salvatierra O Jr: Access to kidney transplantation. Has the United States eliminated income and racial differences? Arch Intern Med 1988;148:2594-2600.
34.
Gaylin DS, Held PJ, Port FK, et al: The impact of comorbid and sociodemographic factors on access to renal transplantation. JAMA 1993;269:603-608.
35.
Chapman JR: Compliance: the patient, the doctor, and the medication? Transplantation 2004;77:782-786.
36.
Ramachandran R, Jha V: Kidney transplantation is associated with catastrophic out of pocket expenditure in India. PLoS One 2013;8:e67812.
37.
Lowe M, Kerridge IH, Mitchell KR. ‘These sorts of people don't do very well': race and allocation of health care resources. J Med Ethics 1995;21:356-360.
38.
Ladin K, Hanto DW: Understanding disparities in transplantation: do social networks provide the missing clue? Am J Transplant 2010;10:472-476.
39.
Clark CR, Hicks LS, Keogh JH, Epstein AM, Ayanian JZ: Promoting access to renal transplantation: the role of social support networks in completing pre-transplant evaluations. J Gen Intern Med 2008;23:1187-1193.
40.
KONOS: 2014 Annual Report. http://www.konos.go.kr (accessed July 2014).
41.
Darr A, Randhawa G: Awareness and attitudes towards organ donation and transplantation among the Asian population. A preliminary survey in Luton, UK. Transpl Int 1999;12:365-371.
42.
Vathsala A: Improving cadaveric organ donation rates in kidney and liver transplantation in Asia. Transplant Proc 2004;36:1873-1875.
43.
Caskey F, Roderick P, Steenkamp R, et al: Social deprivation and survival on renal replacement therapy in England and Wales. Kidney Int 2006;70:2134-2140.
44.
Oniscu GC, Schalkwijk AA, Johnson RJ, Brown H, Forsythe JL: Equity of access to renal transplant waiting list and renal transplantation in Scotland: cohort study. BMJ 2003;327:1261.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.