To evaluate the diagnostic capabilities of a new, ultraportable 2D echo device to detect regional left ventricular wall motion abnormalities, 55 patients underwent an echocardiographic exam at the bedside prior to cardiac catheterization. Left ventricular cineangiograms were obtained in biplane (60°LAO and 30° RAO) in 52 patients and in single plane (30° RAO) in 3 patients. Angiograms were read in a blinded fashion. Wall motion was evaluated in the anterior, septal, apical, inferior and lateral portions of the left ventricle and compared to echo findings. Median study time of the echo exam was 8 min(3.5–15). Ninety-three percent of all left ventricular segments were adequately visualized with echo for evaluation. In 46 patients (83%), the echo study adequately visualized all segments. Echo findings agreed completely with cineangiograms in 91% of patients. The unique portability and diagnostic adequacy of this device justifies its routine use at the bedside where a rapid assessment of cardiac function may assist in clinical decision-making.