... poiesis. The purpose of this investigation was to determine to what ex­ tent the kinetics of eosinophil proliferation can alter in disease. Wickramasinghe/M offatt Materials and Methods 159 Five hacmatologically normal cases, 7 patients with megaloblastic haemopoiesis due to vitamin B12 deficiency, 2...

.... There is no evidence that altered thiamine metabolism is a factor in the disturb­ ance of pyruvate metabolism that occurs in vitamin B12 deficiency, nor that thia­ mine deficiency is involved in the commonly associated neuropsychiatric disorder. Erythrocyte transketolase activity is normal in untreated iron deficiency...

...- Transcobalamins alamin I and II (TCI, TC II) were determined using Vitamin B12 binding S7Co B12. The results were statistically analysed in re- Vitamin B12 deficiency lation to severity of anaemia and vitamin BI2 deficiency. In severe vitamin B12 deficiency, TC II was reduced and contributed to the reduc­ tion...

... was significantly de­ Iron deficiency pressed in 5 out of 7 patients with vitamin B12 or Liver diseases folate deficiency, in 2 of 8 patients with megalo­ Thymidine incorporation blastic changes induced by antipurines and in 2 of 8 Vitamin B12 deficiency patients with a macrocytosis caused by alcoholism. The low...

... inhibitors Vitamin B 12 deficiency Vitamin B 12 uptake Acta Haeraat. 49: 65-73 (1973) Factors Influencing the Uptake of Vitamin B12by Normoblastic and Vitamin B12-Deficient Bone Marrow Cells S. N. W ickramasinghe and Beryl M offatt MRC Experimental Haematology Unit, St. Mary s Hospital Medical School...

...)itcyaien5nd8cy2Ci(p/Hmabtmie4no.tl9s) with folate deficiency (Hb 6.9 and 9.3 g/dl; MCV 105 and 109 fl), and with 100 «Ci 5-3H-uridine (specific activity 24 Ci'mmol) in 1 patient with vitamin B12 deficiency (Hb 7.0 g/dl; MCV 120 fl). All incubations were carried out at 37 °C for 1 h, after which a few small labelled...