...Hannah Levavi; Joseph Tripodi; Bridget Marcellino; John Mascarenhas; Amy V. Jones; Nicholas C.P. Cross; Diana Gruenstein; Vesna Najfeld The JAK2 V617F point mutation has been implicated in the pathogenesis of the vast majority of myeloproliferative neoplasms (MPNs), but translocations involving...

... Cervera The platelet-derived growth factor receptor β (PDGFRB) gene translocations lead to a spectrum of chronic myeloid neoplasms, frequently associated with eosinophilia. Clinical heterogeneity is associated with a molecular one. Here, we report a novel case of a patient harboring a t(5;8)(q33;p22...

...Dolors Costa; Concha Muñoz; Ana Carrió; Amparo Arias; Cándida Gómez; Francesc Solé; Blanca Espinet; Gemma Azaceta; María J. Calasanz; Meritxell Nomdedeu; Xavier Calvo; Elias Campo; Benet Nomdedeu Recurrent translocations are uncommon in myelodysplastic syndromes (MDS). Three new recurrent...

... myelogenous leukemia Karyo­ type Leukemia Marker chromosomes Ph1chromosome Translocation Abstract. Several unusual cytogenetic changes have occurred during the evolu­ tion of chronic myelogenous leukemia in a 32-year-old white male with this dis­ ease for 8 years. The first appearance...

... chromosomal abnormality involving a translocation between chromosomes 3 and 21 was observed, i.e., t(3;21)(p14;q22). A complete remission was never obtained in spite of aggressive chemotherapy and the patient died 8 months after diagnosis. © 1986 S. Karger AG, Basel 1986 Copyright / Drug Dosage...

...M. Gyger; C. Perreault; R. Belanger; Y. Bonny A second example of chronic myeloid leukemia (CML) with the unusual simple variant t(22;22) is reported. In this case, break points are readily identified at bands q13 and q11. The nature of simple variant translocations in CML is discussed in the light...

...A. Caimo; C.M. Parodi; C. Rabitti; S. De Filippi; M. Podestà; A. Bacigalupo; A. Castellaneta; A.M. Marmont A new unusual translocation t (19p+; 22q-) was detected in a 31-year-old female with Philadelphia cromosome (Ph1) positive chronic myeloid leukemia (CML). This translocation has apparently...

... leukemia with an 8; 14 and 14; 18 chromosome translocation. Surface marker studies of the cell line showed that the cells were positive for HLA-DR, CALLA (CD10), Bl (CD20) and B4 (CD19), but negative for Tl 1 (CD2). The fresh cells from peripheral blood of the patient had no surface immunoglobulins...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute nonlymphocytic leukemia Chromosome 11 Chromosome 13 Translocation Case Report Acta Haematol 1992;87:198-201 Kenichi Sugitaa Hidemitsu...

... Medical Center, New York, N.Y., USA Cytogenetic Evidence for Extramedullary Blast Crisis with t(8;13)(q11;p11) in Chronic Myelomonocytic Leukemia Key Words Chronic myelomonocytic leukemia Cytogenetics Extramedullary blast crisis Translocation Abstract A 27-year-old male developed massive generalized...