.... A random-effects meta-analysis was conducted. Patients classed as TI at baseline showed a 59% decrease in the risk of death compared with transfusion-dependent (TD) patients [HR 0.41; 95% credible interval (CrI) 0.29-0.56], and this effect did not appear to interact significantly with illness severity...

.... Transfusion dependence Aplastic anemia Deferasirox Hematopoiesis Iron chelation therapy Aplastic anemia (AA) is a life-threatening bone marrow failure disorder. Many patients with AA require blood transfusions as supportive management, which results in chronic iron overload. Because of the effects...