... vein thrombosis (DVT) diagnosed based on decreased functional and antigenic fibrinogen levels with a decreased functional/antigenic fibrinogen ratio. Definitive diagnosis of congenital hypodysfibrinogenemia is done by genotyping using whole-exome sequencing, which identified the γ326Cys→Tyr mutation...

... with coagulopathy and an increased risk of thrombosis. An association between thrombin generation (TG) capacity, disease severity, and outcomes has not been well described. Methods: We assessed the correlation of TG with sequential organ failure assessment (SOFA) and sepsis-induced coagulopathy (SIC) scores...

.... There were no deaths in the IST alone group. Table 6. Incidence rates of adverse events from IST initiation to last IST-Treated follow-up Paroxysmal nocturnal hemoglobinuria Aplastic anaemia Thrombosis Immunotherapy Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic...

.... Structured follow-up details. Fig. 1. Structured follow-up details. Direct oral anticoagulants Thrombosis Adherence Controls were patients receiving standard care recruited from the cardiology outpatient clinic between May 1, 2019, and October 1, 2020. While visiting the outpatient clinic...

...Amit R. Mehta; Aron Kefela; Charina Toste; Donald Sweet Patients with immune thrombocytopenia (ITP) are at increased risk for bleeding and are paradoxically at increased risk for thrombosis. Many patients with ITP have underlying cardiovascular (CV) disease and/or other thrombotic risk factors...

...Phaedon Dimitrios Zavras; Vikas Mehta; Sanjay Goel; Kith Pradhan; Henny H. Billett Background: Increased rates of thromboembolism (TE) have been reported in patients with COVID-19, even without prior predisposition to thrombosis. Cancer patients are already predisposed to a hypercoagulable state...

... therapeutic regimens in VITT-suspected patients. Here, we report the case of a 26-year-old female patient, who developed bilateral deep vein thrombosis in the lower legs and severe thrombocytopenia after ChAdOx2 nCov-19 vaccination. After initial anticoagulation therapy regimens including fondaparinux...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Mice Viscoelastic coagulation monitor Coagulation Thrombosis...

... of this review was to discuss cytopenias caused by systemic lupus erythematosus and antirheumatic drugs, Felty’s syndrome in rheumatoid arthritis, and autoimmune hemolytic anemia, thrombosis, and thrombotic microangiopathies related to rheumatological conditions such as catastrophic antiphospholipid syndrome...

... neither in the literature nor in the databases HGMD or gnomAD at the time of detection. [email protected] 29 01 2020 7 05 2020 10 7 2020 Protein S deficiency Thrombosis Venous thromboembolism Thrombophilia Unfortunately, we could not perform family studies...

...Siriyakorn Chansai; Supan Fucharoen; Goonnapa Fucharoen; Arunee Jetsrisuparb; Worawan Chumpia Background: Thalassemia is a group of hereditary hemoglobinopathies caused by decreased or absent synthesis of α and/or β globin chains. Studies have shown that hypercoagulability and thrombosis are common...

...Margaret C. Cupit-Link; Amulya Nageswara Rao; Deepti M. Warad; Vilmarie Rodriguez Lemierre syndrome (LS) is a multisystemic infection beginning in the oropharynx and leading to thrombosis of the internal jugular vein (IJV) with septic emboli and potential thrombotic extension to the central nervous...

...A. Girolami; E. Cosi; C. Santarossa; S. Ferrari; A.M. Lombardi Objective: To evaluate the impact of an asymptomatic congenital clotting defect (FXII deficiency) versus that of a similar but symptomatic defect (FXI deficiency) on protection from thrombosis. Patients and Methods: All patients...

...Hung Chang; Ming-Chung Kuo; Lee-Yung Shih; Jin-Hou Wu; Tung-Liang Lin; Po Dunn; Tzung-Chih Tang; Yu-Shin Hung; Po-Nan Wang Patients with acute promyelocytic leukemia (APL) are prone to both bleeding and thrombosis. The bleeding complications are well known. In contrast, APL-associated thrombosis...

... symptoms such as hot flushes, sweating, vaginal atrophy and osteoporosis are a consequence of the decreased estadiol levels. However, climacteric is also responsible for a dramatic increase in the risk of adverse thrombotic events such as myocardial infarction, stroke, deep venous thrombosis and pulmonary...

.... In critically ill patients, various disorders can lead to thrombosis. The combination of hypofibrinolysis and hypercoagulability synergistically enhances the risk of thrombosis, which may occlude arterioles and capillaries and thus give rise to multiple organ dysfunction syndrome [ 1,2 ]. Plasminogen activator...

...Seitaro Kamiya; Masayori Hagimori; Masayoshi Ogasawara; Masayuki Arakawa Thrombosis is characterized by congenital and acquired procatarxis. Nattokinase inhibits thrombus formation in vitro. However, in vivo evaluation of the therapeutic efficacy of nattokinase against thrombosis remains...

... coagulation, mainly FXII. Anecdotal reports on thrombosis in patients with prekallikrein deficiency have occasionally been reported. These involved both arterial and venous thrombosis. The purpose of the present article is to analyze the stories and the clinical pictures of all 75 cases of prekallikrein...

...N.E. Stathakis; A.G. Papayannis; M. Antonopoulos; C. Gardikas A Greek family with hereditary antithrombin III (AT III) deficiency associated with venous thrombosis is reported. 5 members of the family were affected. In these patients, AT III and heparin cofactor activities were decreased...

... and smaller platelet aggregates appeared in the arterial blood. Considerably more guinea pigs died during or after the NaA infusion than after administration of NaL. The possibility that arachidonic acid and other long-chain fatty acids may play a role in the development of thrombosis and thromboembolism...