... with thrombosis management; brain metastasis, malignancies of the gastrointestinal tract, drug-drug interactions (DDIs), and thrombocytopenia. By reviewing current literature, we suggest our clinical approach for managing these cases in the era of DOACs. Key Messages: (1) The management of patients with brain...

...Jingbo Yu; Emily Bland; Tammy Schuler; Thomas Cordaro; Evan Braunstein Introduction: Ruxolitinib is approved for treatment of myelofibrosis. We evaluated ruxolitinib in patients with anemia (hemoglobin <10 g/dL) or thrombocytopenia (platelet count ≤100 × 10 9 /L) at diagnosis. Methods...

...Soo Min Ahn; Eun-Ji Choi; Ji Seon Oh; Yong-Gil Kim; Chang-Keun Lee; Bin Yoo; Seokchan Hong Introduction: We aimed to identify the clinical characteristics and risk factors for chronic immune thrombocytopenia (ITP) in patients with systemic lupus erythematosus (SLE). Methods: We retrospectively...

...Adi Sherban; Ragda Hussen; Anat Gafter-Gvili; Alla Atamna; Jihad Bishara; Pia Raanani; Kim Ben Tikva Kagan; Tomer Avni Introduction: Influenza virus causes significant global annual morbidity and mortality. Thrombocytopenia is recognized as a poor prognostic factor in sepsis and is associated...

... or acute myeloid leukemia and grade 4 thrombocytopenia (<25 × 10 9 platelets/L). Approximately 30–65% of patients in this open-label extension phase experienced clinically relevant thrombocytopenic events; no conclusions could be made regarding long-term efficacy (non-randomized design, no placebo...

...Marcel Kemper; Georg Lenz; Rolf Michael Mesters Vaccine-induced immune thrombotic thrombocytopenia (VITT) has already been described after vaccination with ChAdOx2 nCov-19 (AstraZeneca) and Ad26.COV2.S (Johnson & Johnson/Janssen). However, less knowledge so far has been gained about optimal...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Thrombocytopenia Anemia Leukopenia Thrombosis Thrombotic microangiopathy Rheumatic...

...Bora Son; Hee sue Park; Hye Sook Han; Hee Kyung Kim; Seung Woo Baek; Yaewon Yang; Ki Hyeong Lee; Jihyun Kwon Acquired amegakaryocytic thrombocytopenia (AAMT) is a rare disease that causes severe bleeding. The pathogenesis and treatment of AAMT have not yet been defined. We report the case of a 60...

... ALC, and platelet counts. Cox regression was used to analyze the risk factor for survival. Results: Patients with a higher eNLR (≥3), lymphopenia (< 1,000/μL), and thrombocytopenia (< 150 K/μL) had an inferior progression-free survival (PFS) and overall survival (OS) compared...

...; Kazuya Sato; Iekuni Oh; Ken Ohmine; Kazuo Muroi; Kentaro Ashizawa; Yu Yamamoto; Hisashi Oshiro; Yoshinobu Kanda TAFRO syndrome, a rare systemic inflammatory disease, can lead to multiorgan failure without appropriate treatment. Although thrombocytopenia is frequently seen in patients with TAFRO syndrome...

.... Hematology/oncology Platelet transfusion Supportive care Thrombocytopenia Platelet refractoriness Primary Objective The primary objective of this study was to evaluate the effectiveness of ESDT compared to the standard method of platelet transfusion in thrombocytopenic hemato-oncological...

...Abdul Shlebak; Anthony Poles; Richard Manning; Shaikha Almuhareb; Josu De La Funte; Mike Mitchell; Geoff Lucas Background: Bernard-Soulier syndrome (BSS) is a congenital bleeding disorder characterised by thrombocytopenia, giant platelets and decreased platelet adhesion resulting from genetic...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Thrombocytopenia Ethylenediaminetetraacetic acid-dependent pseudothrombocytopenia (EDTA-PTCP) is a phenomenon...

... was supported by grants from the Swiss National Science Foundation (PP00P3_128461/1) and the Olga Mayenfisch Stiftung (both to M.S.). In conclusion, we could not detect an effect of SSRI or non-SSRI treatment on bleeding events in patients with severe thrombocytopenia induced by chemotherapy. SSRIs [e.g...

...Anders Møller; Ole Weis Bjerrum; Arash Afshari Background/Aims: Thrombocytopenia and the increasing use and variety of antithrombotic drugs is a challenge prior to lumbar puncture. This study examined the Danish haematology practice regarding drug pausation, assessment of haemostasis and whether...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Thrombocytopenia Sea-blue histiocytosis in bone marrow is a morphological finding that has been described...

... of myosin-9 as a pathognomonic sign of the disorder. Thrombosis and Haemostasis 2010a;103:826-832. 7. Balduini CL, Pecci A, Savoia A: Recent advances in the understanding and management of MYH9 -related inherited thrombocytopenias. Br J Haematol 2011;154:161-174. 8. Kunishima S, Saito H: Advances...

... was followed by sustained improvement in platelet count in both patients. To our knowledge, this is the first report of ITP in association with C. albicans infection. A 43-year-old woman with diabetes mellitus on oral hypoglycemic agents presented with severe thrombocytopenia. Her platelet count on admission...

...Hung Chang; Tzung-Chih Tang Acquired amegakaryocytic thrombocytopenia (AAMT) is an entity characterized by severe thrombocytopenia with a significantly reduced number of megakaryocytes in the bone marrow. AAMT is rare and poorly defined. Therefore, standard treatment is not well established...

... prominence to the periodical reevaluation of all the etiological hypotheses of thrombocytopenia in relation to its clinical condition. The majority of chronic ITP children do not require treatment, especially if bleeding is absent or minimal. The treatment decision depends on several factors other than...