.... Results: Our results showed that the S1P receptors (S1PRs) 1, 4 and 5 were the predominantly expressed neutrophil S1PRs at the cDNA level. After pretreatment with S1P, the fMLP-activated neutrophils released increased levels of superoxide anions. PI3K and Akt proteins were involved in the signaling...

...M. de Martino; M.E. Rossi; M. Resti; C. Vullo; A. Víerucci Superoxide anion production in resting and PMA- or zymosan-stimulated neutrophils was evaluated in 21 β -thalassemia patients. The results were correlated with ferritin values, hepatitis B virus serum markers, liver pathology...

... Neutrophils, canine Superoxide anion Transplantation of hemopoietic stem cells has improved the life of many patients suffering from leukemia and other malignant diseases. Bone marrow transplantation techniques have evolved due to the knowledge gained from animal models. In large outbred animals like...