... Introduction: Stroke is a severe complication of sickle cell anemia (SCA), with devastating sequelae. Transcranial Doppler (TCD) ultrasonography predicts stroke risk, but implementing TCD screening with suitable treatment for primary stroke prevention in low-resource environments remains challenging. SPHERE...

...Anna L. Slingerland; Madeline B. Karsten; Edward R. Smith; Amy E. Sobota; Alfred P. See Moyamoya syndrome increases the risk of stroke in sickle cell disease, but revascularization surgery can modify this risk. Collaborative management between hematology and neurosurgery offers effective strategies...

...Bindu Kanathezhath Sathi; Yilin Yoshida; Michael Raymond Weaver; Lila S. Nolan; Barbara Gruner; Vinod Balasa; Talissa Altes; Carlos Leiva-Salinas Introduction: Unlike homozygous hemoglobin SS (HbSS) disease, stroke is a rare complication in hemoglobin SC (HbSC) disease. However, recent studies have...

.... Acquired hemophilia A Coagulation Hemostasis Stroke A 94-year-old man was admitted to the emergency room with symptoms of transitory neurologic deficit reported as speech disturbances and facial asymmetry of 15-min duration. Symptoms were consistent with a left carotid transient ischemic attack...

...Zhen Zhao; Ruixue Wang; Zhijun Huo; Chunlei Li; Zhiyong Wang Sphingosine 1-phosphate (S1P) is a highly active lysophospholipid implicated in various cardiocerebrovascular events such as coagulation, myocardial infarction and stroke. However, as the functional S1P receptor antagonist, whether...

...Perla Vicari; Gisele Sampaio Silva; Maria Aparecida Eiko Nogutti; Faustino Moreira Neto; Normélia Jesus dos Santos; Ayrton Roberto Massaro; Maria Stella Figueiredo Stroke is a serious complication of sickle cell anemia (SCA) affecting children and adults. Recent reports suggested that tumor...

...William J. Savage; Allen D. Everett; James F. Casella A 12-year-old boy with HbSS sickle cell disease (SCD) was admitted with an acute febrile illness and developed overt stroke 3 days later. Plasma glial fibrillary acidic protein levels were elevated, as compared to pediatric controls, 32 h prior...

...Mariana Bonduel; Gabriela Sciuccati; Mirta Hepner; Graciela Pieroni; Aurora Feliú Torres; Juan Pablo Frontroth; Silvia Tenembaum Over a 12-year period, 112 consecutive children with arterial ischemic stroke (AIS) and 38 children with cerebral venous thrombosis (CVT) were prospectively recruited...