..., splenectomy has been considered one of the most effective treatments for splenomegaly, reducing clinical severity among thalassemia patients. Thus, we aim to investigate the differences in splenectomy rates and hematological indices among thalassemia patients with different genotypes. Method: In this study...

...Daehun Kwag; Jae-Ho Yoon; Gi June Min; Sung-Soo Park; Silvia Park; Sung-Eun Lee; Byung-Sin Cho; Ki-Seong Eom; Yoo-Jin Kim; Hee-Je Kim; Seok Lee; Chang-Ki Min; Seok-Goo Cho; Dong-Wook Kim; Jong Wook Lee Objectives: Although splenectomy has long been second-line option for immune thrombocytopenia...

...Yuen-Chin Ong; Hung Chang; Ta-Sen Yeh; Ming-Chung Kuo; Pei-Ling Li; Po-Nan Wang; Tung-Liang Lin; Jin-Hou Wu; Yu-Shin Hung Introduction: Splenectomy is an important and potentially curative treatment for immune thrombocytopenia (ITP). Laparoscopic splenectomy (LS) has replaced open splenectomy (OS...

... physicians seem reluctant to recommend splenectomy for elderly patients with immune thrombocytopenia (ITP), we investigated the safety and efficacy of splenectomy and the predictive factors for response in these patients. Methods: 184 patients with primary ITP were retrospectively analyzed based on age...

.... Hemolysis Splenectomy Thalassemia Thrombophilia Hemoglobin (Hb) E/β-thalassemia (E/β-Thal) disease is a very common hereditary hemolytic anemia in Thailand. Globally, it is the most common form of the symptomatic thalassemic syndromes [ 1 ], and its clinical and hematological features are those...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2013 Iron chelation Iron overload Splenectomy Transfusion As a group, the thalassemias are the most common single gene disorder in the world. They are found at high...

..., the frequency and risk factors of PHT in patients with hemoglobin H (HbH) disease is unknown. The purpose of this study was to identify the prevalence of PHT risk manifested as tricuspid regurgitant jet velocity (TRV) ≥2.5 m/s in patients with HbH disease and its correlation with splenectomy. One hundred...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Immunoglobulins Splenectomy Thalassaemia Acta haemat. 46: 267-270...

...B. Dube; H.S. Bajpai; S.C. Chawla; Y.N. Gupta A 43-year-old female, when subjected to splenectomy for obscure splenomegaly, gradually developed an increasing bleeding diathesis. About 20 months after splenectomy, her platelets numbered 1.3 millions/mm 3 and showed complete absence of aggregation...

...A. Fertakis; G. Panitsas; B. Angelopoulos Serum haemopexin levels were determined by the radial immunodiffusion method in 96 patients with β -thalassaemia major (27 after splenectomy), in 36 with sickle cell disease and in 18 with sickle cell-thalassaemia disease (4 after splenectomy). Lowering...

...B. Speck; M. Kissling Aplastic anemia was produced with 32 P in rabbits with and without splenectomy. Transient hemopoietic engraftment without graft versus host (GvH) was seen after conditioning with antilymphocyte serum (ALS) and infusion of allogeneic marrow from a strain that is known to cause...

... predominantly of the myeloid type. A combination of thymectomy and splenectomy was used because of the inhibitory effect of splenectomy in virus-induced myeloid leukemias. Injection of virus from selected lymphatic leukemias into double-operated animals reduced the incidence of leukemias to 13%. In the bone...

.... Brucellosis Thalassaemia Splenectomy Blood transfusion A d a haemat. 55: 244-249 (1976) Brucellosis in Two Thalassaemic Patients Infected by Blood Transfusions from the Same Donor J. Economidou, P. Kalafatas, T. Vatopoulou, D. P etropoulou and C. Kattamis Hellenic Red Cross Blood Research Laboratory...

... with normal controls. Study of those patients who underwent splenectomy suggests that neutrophil function can be improved by splenectomy. The possible causes of defective function in this disease are discussed. Acta haemat. 62: 191-198 (1979) Microbicidal Function of the Neutrophils in Hairy-Cell Leukaemia J...

...) the clinical course of the patient with Hb Istanbul before splenectomy was more severe when compared with that of the individual with Hb Saint-Etienne; (2) although Hb F was found within normal range in the individual with Hb Istanbul, a high level of Hb F (19%) was observed in the patient with Hb Saint...

...A. Kendall; S. Young; N. Oune; B. Wiltshire; H. Lehmann A fifth family with the unstable Hb Genova is reported from Kenya, East Africa. This almost certainly represents an independent mutation. The beneficial effect of splenectomy has been carefully assessed in one member of the family. 8 08...

...Joel A. Spero; Jessica H. Lewis; Ute Hasiba; L.W. Gumerman A 13-year-old boy developed thrombocytopenic purpura in 1953 which improved during 4 weeks of cortisone therapy. Following 13 years of intermittent symptoms the platelet count was found to be 8,000/ μ l. After splenectomy the patient...

... in combination with enhanced phospholipid-phosphate metabolism and decreased activity of the membrane-stabilizing enzyme lysolecithin-acyl-transferase. In all cases splenectomy beneficially influenced the hemolytic process. Family studies revealed a dominant-autosomal genetic transmission. 3 3 2009 ©...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Complement in ITP Immunoglobulins ITP Splenectomy Acta haemat. 56: 205-211...

...E. Okon; I.S. Levij; E.A. Rachmilewitz In order to evaluate the interrelations of splenectomy, iron overload and cirrhosis, histologic specimens of liver and spleen were examined and correlated in 12 children with β -thalassemia major. All patients had received blood transfusions since infancy...