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Keywords: Somatic hypermutation
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Journal Articles
Why Is the Immunoglobulin Heavy Chain Gene Mutation Status a Prognostic Indicator in Chronic Lymphocytic Leukemia?
Available to Purchase
Journal:
Acta Haematologica
Acta Haematol (2018) 140 (1): 51–54.
Published Online: 16 August 2018
... that of patients with mutated IgHV is unknown. CLL cells with unmutated IgHV were thought to originate from naïve B lymphocytes, whereas CLL cells with mutated IgHV were thought to arise from B cells that have undergone somatic hypermutation (SHM). Cell surface protein expression profile and gene expression...
