... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Iron homeostasis Oral sucrosomial iron Refractory anemia Myelodysplastic syndrome Cost-effectiveness Refractory anaemia (RA) affects 1 case/100,000 population...

...Nicolas E. Stathakis; Anthony S. Gidari; Richard D. Levere The responsiveness to erythropoietin of cultured bone marrow cells, obtained from 7 patients with refractory anemia with hyperplastic marrow, was studied. 5 of these patients’ marrows also exhibited sideroblastic changes. Heme synthesis...

...Paolo Ricci; Michele Baccarani; Alfonso Zaccaria; Maria Alessandra Santucci; Sante Tura Refractory anemia (RA) is an hematologic disorder at risk of developing into a malignancy (hemopoietic dysplasia). Information on hemopoietic dysplasias is useful for sharpening the appropriate diagnostic...

...P. Carbone; G. Barbata; G. Granata; G. Margiotía; F. Caronia Statistical analysis (( χ 2 test) of the interchromosomal distribution of sister chromatid exchanges in bone marrow cells from 3 patients with refractory anemia showed significant differences concerning chromosome 1. Analysis...

...Lawrence R. Solomon; Robert S. Hillman; Clement A. Finch The relationship between the level of erythropoiesis and iron balance was evaluated in 13 subjects with idiopathic refractory anemias. Serum ferritin levels and bone marrow iron stores were increased only in those patients with ring...

...A. Nagler; B. Brenner; I. Tatarsky A case of refractory anemia with an excess of blasts in transformation, secondary to irradiation, and leading ultimately to acute lymphoblastic leukemia, is presented. Commonalities and differences between acute lymphoblastic and nonlymphoblastic leukemias...

...L. Annino; S. Di Giovanni; L., Jr. Tentorí; A. Cafolla; M.P. Nanni Costa; M.L. Salvagnini; G. Angeli A new case of refractory anemia with excess of blasts (RAEB) with acquired Hemoglobin H disease (HbH) evolving into acute nonlymphoid leukemia (ANLL) is reported. In this patient, both family...

...Masashi Adachi; Ryukichi Ryo; Akinori Yoshida; Nobuo Yamaguchi; Yoichiro Izumi A 72-year-old man with refractory anemia (RA) developed overt megakaryoblastic leukemia after the course of RA with excess of blasts. The blasts were positive for platelet peroxidase activity and had platelet...

...Franco Leoni; Stefania Ciolli; Giovanni Longo; Andrea Messori; Pierluigi Rossi Ferrini Twenty patients with primary myelodysplastic syndromes (16 refractory anemia without or with ringed sideroblasts, 2 refractory anemia with excess blasts, 2 refractory anemia with excess blasts in transformation...

...A. Gürgey; A. Rötig; F. Gümrük; R. Cemeroğlu; F. Sanalioğlu; C. Altay Two unrelated infants, 1 female and 1 male, with Pearson’s syndrome are presented. Both patients presented with severe macrocytic refractory anemia starting early in infancy. Investigation of the mitochondrial (mt), DNA showed...

...Akira Matsuda; Motohiro Misumi; Tsuneyuki Shimada; Katsuhiko Yoshida; Fumiharu Yagasaki; Yoshihiro Ito; Nobutaka Kawai; Ikuo Murohashi; Kunitake Hirashima; Masami Bessho Myelodysplastic syndromes (MDS), especially refractory anemia (RA) are very heterogeneous diseases regarding their morphological...

... when the incidence of autoantibodies and number of red blood cell transfusions were compared (p = 0.334). Patients with refractory anemia and refractory anemia with ringed sideroblasts subtypes had a higher incidence of allo-/autoantibodies than other MDS subtypes (p = 0.03). Conclusion: Patients...