... in the size range of ribosomal precursor RNA was observed, presumably due to an unbalance between rate of synthesis and rate of processing of 45 S RNA Leukemic cells Ribosomes RNA synthesis © 1971 S. Karger AG, Basel 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

...B.W.B Chan In an autoradiographic investigation, it was found that the inhibition of RNA synthesis in human leukaemic blast cells by actinomycin D (AMD) is dose and time dependent. Chase studies with AMD showed that most of the rapidly labelled RNA is unstable. The decay pattern is biphasic, being...

...B.W.B. Chan Cell size can be used to distinguish between the proliferative and the non-proliferative or resting cells in human acute leukaemia. The large, proliferative blast cells not only have a higher rate of RNA synthesis, but also synthesise more labile RNA, compared to the smaller, resting...

... of the perinuclear space, the clumping of cytoplasmic organelles near the nucleus and a reduction in the electron density and ribosome content of the cytoplasm. Most of these grossly abnormal cells suffered from either a marked depression or an arrest in protein and RNA synthesis, and were presumably destined...

... Leukaemia Lymphocytes RNA synthesis Ribosomal RNA Methylation Polysomes Polyacrylamide gel electrophoresis © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...J. Levi; H. Bessler; I. Hirsch; M. Djaldetti The in vitro effect of parathyroid hormone (PTH) on RNA and heme synthesis by embryonic mouse liver erythroid precursors was examined. PTH produced a dose-dependent effect on RNA synthesis. A maximal increase of 60 ± 16% (p < 0.02) was observed...

... School, University of London, London Key Words. Bone marrow DNA synthesis Folate deficiency Megaloblastic haemopoiesis RNA synthesis Vitamin B12 Deficiency Abstract. The in vitro incorporation of various radioactive precursors into the DNA and RNA of nucleated bone marrow cells was studied...