... recipient and donor red blood cells. The underlying mechanism of HHS is not fully understood and proper management can be difficult. Furthermore, there are few reports regarding HHS in pregnancy. We report on the development and management of HHS in a pregnant woman with known compound sickle cell disease...

...Tamar Tadmor; Guy Melamed; Hillel Alapi; Sivan Gazit; Tal Patalon; Lior Rokach Pregnancies following diagnosis of chronic lymphocytic leukemia (CLL) are rare events, mainly because the disease is typically diagnosed in the elderly. Literature on the topic is based only on case reports, and limited...

...Bárbara Marques; Catarina Nora; Daniela Coelho; Patrícia Martinho; Teresa Fidalgo; Marília Gomes; Letícia Ribeiro; Catarina Geraldes; José Pedro Carda Thrombotic microangiopathy is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ injury. Pregnancy-associated...

... and phlebotomies to maintain haematocrit <50% while monitoring iron stores to avoid severe deficiency detrimental to the foetus. Despite normal initial foetal growth, the pregnancy was complicated by preterm birth due to chorioamnionitis. The placenta showed no signs of thrombotic events. The published reports...

...Christiane Delbrück; Wolfgang Miesbach Introduction: Women with von Willebrand disease (VWD) are at a higher risk of bleeding, which might affect the health of mother and child during pregnancy and the intra- and postpartum periods. This retrospective cohort study evaluates changes...

... C deficiency, protein S deficiency, antiphospholipid antibodies syndrome, and combined defects). Three blood samples were collected during pregnancy (i.e., at 16, 20, and 24 weeks) and tested for activated partial thromboplastin time and prothrombin fragment F1 + 2 (F1 + 2); anti-FXa activity...

... diagnosis was confirmed by demonstration of a R1306W mutation, through her first pregnancy. The patient's von Willebrand factor (VWF) antigen and VWF ristocetin cofactor levels rose throughout pregnancy, with an associated drop in the platelet count. The patient was successfully managed through labour...

...Maria Gabriella Mazzucconi; Vitaliana De Sanctis; Marco Alfò; Maria Antonietta Amendolea; Laura Conti; Cristina Santoro; Erminia Baldacci; Monica Peraino; Cesare Masala Objective: To assess the risk of adverse pregnancy outcomes in patients with acquired and/or congenital thrombophilia factors...

...Paolo Ricchi; Silvia Costantini; Anna Spasiano; Tiziana Di Matola; Patrizia Cinque; Luciano Prossomariti In this report, we present a case of a spontaneous pregnancy in a 42-year-old thalassemic woman referred to our Microcythemic Unit while she was on deferasirox (DFX) therapy. The patient had...

...V. Alevizou-Terzaki; H. Gyftaki; A.S. Vrettos; M. Kesse-Elias; M. Mavrikakis Although iron-binding capacity increases during pregnancy, there is no correlation of it with mean values of serum iron and haemoglobin levels. The administration of drugs (vitamins or vitamins + iron) do not influence...

...W.A. Fortune; J.R. Cox Following the failure to discover significant factor VIII and IX levels in a 14-week male fetus, from a pregnancy terminated because the mother was a known carrier of Christmas disease, these factors were measured in 10 other apparently normal fetuses. In no case...

...T. Markkanen; P. Himanen; R.-L. Pajula; S. Ruponen; O. Castrén Binding of serum folic acid activity (FAA) to the protein fractions during and after pregnancy was studied by DEAE Sephadex A-50 gel chromatography. Towards the end of pregnancy, this binding increased. The increase was particularly...

...A. Vrettos; J. Mantzos; G. Kokini; E. Gyftaki The increase of iron-binding capacity during pregnancy is not influenced by the increased production of oestriol from the fetoplacental unit. 4 3 2009 © 1973 S. Karger AG, Basel 1973 Copyright / Drug Dosage / Disclaimer Copyright: All...

...H.C. Ong Haemoglobin E complicates 22.2% of pregnancy in Malaysian aborigines, the prevalence of variants E associated with pregnancy being, 15.8% with Hb E trait abnormality, 3.9% with Hb E homozygous disease, and 2.5% with Hb E thalassaemia disease. Minor haematological abnormalities occur...

...R. Corrocher; L.M. Bambara; M.L. Pachor; D. Biasi; A. Stanzial; G. de Sandre Total and unsaturated folate binding capacity (TFBC, UFBC) have been measured in sera of selective groups of patients to study the role of cell turnover, cell necrosis and the effect of pregnancy in determining...

...Garret FitzGerald; Donald McCarthy; Liam G. O’Connell; Shaun R. McCann 3 cases of hyperimmune thrombocytopenia in pregnancy are described. Splenectomy was followed by return of the platelet count to normal in all. There was no maternal or fetal death. Short Communication Acta haemat. 59: 315-316...

...H.C. Ong; J.C. White; T.A. Sinnathuray A case of haemoglobin H (HbH) disease associated with pregnancy is presented and discussed in the light of reports in the literature. The variable symptomatology is commented upon, although mild to moderate chronic haemolytic anaemia seems to be a constant...

..., (2) 100 normal, non-pregnant females, (3) 50 females in the last trimester of pregnancy, (4) 15 patients with a persistent neutrophil leucocytosis and (5) 20 patients with polycythaemia rubra vera, essential thrombocythaemia or myelofibrosis. A different relationship appeared to exist between...

...Chun Yang; Murray Nussbaum; Hydow Park A 24-year-old Chinese female developed fever, fluctuating neurological and renal manifestations, microangiopathic hemolytic anemia, and thrombocytopenia during the 11th week of her first pregnancy. Therapy for thrombotic thrombocytopenic purpura (TTP...

... than the non-pregnant. The relationship between the stage of gestation and in vitro autohaemolysis in normal pregnancy may be fitted by a quadratic curve. 5 02 1980 27 02 1980 27 2 2009 © 1980 S. Karger AG, Basel 1980 Copyright / Drug Dosage / Disclaimer Copyright: All rights...