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Keywords: Ponatinib
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2020) 143 (3): 217–231.
Published Online: 07 October 2019
... in frontline but also in further lines of therapy. The third-generation TKI ponatinib has demonstrated efficacy in patients with refractory CML and Ph+ ALL. Ponatinib is currently the most potent TKI in this setting demonstrating activity against T315I mutant clones. However, ponatinib’s safety data revealed...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Hematology , Oncology
Acta Haematol (2018) 140 (2): 67–70.
Published Online: 05 September 2018
... revealed hypercellular marrow with eosinophilia and fluorescence in situ hybridization identified the FIP1L1-PDGFRα rearrangement. The patient was successfully treated with imatinib. Within months he relapsed and converted into acute myeloid leukemia. The patient was then treated with ponatinib which...